Hexa (hexosaminidase A) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Hexa (hexosaminidase A) Mus musculus
Analyze
Symbol: Hexa
Name: hexosaminidase A
RGD ID: 10707
MGI Page MGI
Description: Enables beta-N-acetylhexosaminidase activity. Involved in dermatan sulfate catabolic process and hyaluronan catabolic process. Acts upstream of or within several processes, including adult walking behavior; ganglioside catabolic process; and nervous system development. Located in membrane. Is active in lysosome. Is expressed in brain; mandible; and maxilla. Used to study Tay-Sachs disease. Human ortholog(s) of this gene implicated in Tay-Sachs disease. Orthologous to human HEXA (hexosaminidase subunit alpha).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: beta-hexosaminidase subunit alpha; beta-N-acetylhexosaminidase subunit alpha; Hex-1; hexosaminidase subunit A; N-acetyl-beta-glucosaminidase subunit alpha
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39959,446,966 - 59,472,392 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl959,446,823 - 59,472,392 (+)EnsemblGRCm39 Ensembl
GRCm38959,539,540 - 59,565,109 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl959,539,540 - 59,565,109 (+)EnsemblGRCm38mm10GRCm38
MGSCv37959,387,474 - 59,412,912 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36959,337,673 - 59,363,111 (+)NCBIMGSCv36mm8
Celera956,766,853 - 56,792,230 (+)NCBICelera
Cytogenetic Map9BNCBI
cM Map932.02NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (ISO)
(1->4)-beta-D-glucan  (EXP)
1,1-dichloroethene  (EXP)
1,2-dimethylhydrazine  (EXP)
1-chloro-2,4-dinitrobenzene  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2,4-dinitrotoluene  (ISO)
3-chloropropane-1,2-diol  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-diaminodiphenylmethane  (EXP)
6-propyl-2-thiouracil  (ISO)
all-trans-retinoic acid  (ISO)
amiodarone  (ISO)
apigenin  (EXP,ISO)
Aroclor 1254  (EXP)
azoxystrobin  (ISO)
benzo[a]pyrene  (EXP,ISO)
beta-lapachone  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
carbon nanotube  (EXP)
CGP 52608  (ISO)
clofibrate  (EXP)
compound 48/80  (ISO)
copper atom  (EXP)
copper(0)  (EXP)
copper(II) chloride  (EXP)
cyclosporin A  (ISO)
deguelin  (ISO)
dexamethasone  (EXP,ISO)
diuron  (ISO)
divanadium pentaoxide  (EXP)
dorsomorphin  (ISO)
endosulfan  (ISO)
flunarizine  (ISO)
flutamide  (EXP,ISO)
folic acid  (EXP)
folpet  (EXP)
gentamycin  (ISO)
glafenine  (ISO)
indometacin  (ISO)
inulin  (EXP)
isoprenaline  (EXP)
ivermectin  (ISO)
mercury dibromide  (ISO)
methimazole  (ISO)
methyl methanesulfonate  (ISO)
Mibefradil  (ISO)
N(4)-hydroxycytidine  (EXP)
N,O-dimethyltyramine  (ISO)
nefazodone  (ISO)
paracetamol  (EXP)
perfluorohexanesulfonic acid  (EXP)
perfluorooctane-1-sulfonic acid  (EXP)
phenobarbital  (EXP)
phosphorus atom  (ISO)
phosphorus(.)  (ISO)
pyrimidifen  (ISO)
resveratrol  (ISO)
rotenone  (EXP,ISO)
SB 431542  (ISO)
sodium arsenite  (ISO)
sodium fluoride  (EXP)
Soman  (ISO)
sulfadimethoxine  (ISO)
tacrolimus hydrate  (EXP)
tamoxifen  (EXP)
tetrachloromethane  (EXP,ISO)
titanium dioxide  (EXP)
valproic acid  (ISO)
vinclozolin  (ISO)
Yessotoxin  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
2. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
3. MGDs mouse GO annotations MGD data from the GO Consortium
4. MGD IEA MGD IEA
5. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
6. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
7. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
8. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
9. Mouse MP Annotation Import Pipeline RGD automated import pipeline
10. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
11. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
12. Murine Sialidase Neu3 facilitates GM2 degradation and bypass in mouse model of Tay-Sachs disease. Seyrantepe V, etal., Exp Neurol. 2018 Jan;299(Pt A):26-41. doi: 10.1016/j.expneurol.2017.09.012. Epub 2017 Sep 30.
Additional References at PubMed
PMID:1054503   PMID:1379046   PMID:1427837   PMID:1674729   PMID:1914521   PMID:6458607   PMID:7063884   PMID:7550345   PMID:7833835   PMID:7896264   PMID:7937929   PMID:7959736  
PMID:8147878   PMID:8634145   PMID:8649810   PMID:8747922   PMID:8789434   PMID:8896570   PMID:9103204   PMID:9184660   PMID:9223328   PMID:9237263   PMID:9302266   PMID:9417048  
PMID:9545490   PMID:9645704   PMID:9728334   PMID:9728335   PMID:9828124   PMID:9988215   PMID:10021458   PMID:10196372   PMID:10319820   PMID:10349636   PMID:10591618   PMID:10591619  
PMID:10922068   PMID:11042159   PMID:11076861   PMID:11707436   PMID:11854359   PMID:11919180   PMID:12270683   PMID:12477932   PMID:12904583   PMID:14610273   PMID:14681479   PMID:14972652  
PMID:15782199   PMID:16141072   PMID:16141073   PMID:16602821   PMID:16982810   PMID:17103052   PMID:17883393   PMID:18799693   PMID:19166507   PMID:20862357   PMID:21267068   PMID:21565611  
PMID:21677750   PMID:21873635   PMID:22451654   PMID:23390484   PMID:27453479   PMID:28728022   PMID:30333137   PMID:30550785   PMID:32325033   PMID:33219123   PMID:33966596   PMID:34156977  
PMID:34201771   PMID:34800307   PMID:35449600   PMID:36928510   PMID:38132111  


Genomics

Comparative Map Data
Hexa
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39959,446,966 - 59,472,392 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl959,446,823 - 59,472,392 (+)EnsemblGRCm39 Ensembl
GRCm38959,539,540 - 59,565,109 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl959,539,540 - 59,565,109 (+)EnsemblGRCm38mm10GRCm38
MGSCv37959,387,474 - 59,412,912 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36959,337,673 - 59,363,111 (+)NCBIMGSCv36mm8
Celera956,766,853 - 56,792,230 (+)NCBICelera
Cytogenetic Map9BNCBI
cM Map932.02NCBI
HEXA
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381572,340,924 - 72,376,014 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1572,340,924 - 72,376,420 (-)EnsemblGRCh38hg38GRCh38
GRCh371572,633,265 - 72,668,355 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361570,422,832 - 70,455,457 (-)NCBINCBI36Build 36hg18NCBI36
Build 341570,422,832 - 70,455,393NCBI
Celera1549,521,918 - 49,554,688 (-)NCBICelera
Cytogenetic Map15q23NCBI
HuRef1549,466,005 - 49,498,776 (-)NCBIHuRef
CHM1_11572,753,786 - 72,786,527 (-)NCBICHM1_1
T2T-CHM13v2.01570,157,399 - 70,192,818 (-)NCBIT2T-CHM13v2.0
Hexa
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8868,832,524 - 68,857,462 (+)NCBIGRCr8
mRatBN7.2859,936,526 - 59,961,654 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl859,936,660 - 59,962,013 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx865,458,741 - 65,483,646 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0863,731,762 - 63,756,562 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0861,601,107 - 61,626,013 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0864,325,435 - 64,350,775 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl864,325,435 - 64,350,773 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0864,087,247 - 64,112,587 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4863,363,219 - 63,388,146 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1863,382,272 - 63,407,200 (+)NCBI
Celera859,378,288 - 59,403,211 (+)NCBICelera
Cytogenetic Map8q24NCBI
Hexa
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554504,790,268 - 4,806,734 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554504,790,342 - 4,806,862 (+)NCBIChiLan1.0ChiLan1.0
HEXA
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21661,548,795 - 61,643,064 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11565,707,784 - 65,807,320 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01551,235,123 - 51,326,832 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11570,034,232 - 70,090,688 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1569,998,866 - 70,033,749 (-)Ensemblpanpan1.1panPan2
PanPan1.1 Ensembl1570,057,943 - 70,090,688 (-)Ensemblpanpan1.1panPan2
HEXA
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13035,836,788 - 35,862,525 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3035,772,553 - 35,799,681 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03036,041,265 - 36,068,396 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3036,039,878 - 36,068,382 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13035,993,838 - 36,020,876 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03036,021,266 - 36,048,385 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03036,277,065 - 36,304,204 (-)NCBIUU_Cfam_GSD_1.0
Hexa
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640113,863,160 - 113,890,243 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647131,709,491 - 31,738,245 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647131,712,485 - 31,738,273 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HEXA
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl760,878,284 - 60,913,339 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1760,878,531 - 60,911,537 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2765,420,894 - 65,453,741 (+)NCBISscrofa10.2Sscrofa10.2susScr3
HEXA
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12611,081,985 - 11,130,366 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2611,082,468 - 11,116,075 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666048130,463,174 - 130,496,786 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Hexa
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247811,686,384 - 1,714,684 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247811,686,818 - 1,706,044 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Hexa
615 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:255
Count of miRNA genes:224
Interacting mature miRNAs:244
Transcripts:ENSMUST00000026262
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301782Chol11_mcholesterol 11 (mouse)Not determined92929292963293072Mouse
11532712Sluc39d_msusceptibility to lung cancer 39d (mouse)92558748559587581Mouse
12790986Pcho9_mplasma cholesterol 9 (mouse)93809957572099575Mouse
12790990Tgl7_mtriglyceride 7 (mouse)95455996088559960Mouse
14746993Manh66_mmandible shape 66 (mouse)94981404883814048Mouse
12790992Arlsq1_maortic root lesion size QTL 1 (mouse)93809957572099575Mouse
1301252Etohc3_methanol consumption 3 (mouse)Not determined93503447869034599Mouse
4141224Dxmod_mdoxorubicin nephropathy modifier (mouse)Not determined49452421101406120Mouse
1357709Si5lq3_mserum IGFBP-5 level QTL 3 (mouse)Not determined93311102567111140Mouse
12791002Arlsq2_maortic root lesion size QTL 2 (mouse)93809957572099575Mouse
1301558Stheal8_msoft tissue heal 8 (mouse)Not determined94348071477480860Mouse
1357746Vtbt7_mvertebral trabecular bone trait 7 (mouse)Not determined93073991564740021Mouse
1301172Fembrs6_mfemur breaking strength 6 (mouse)Not determined95902438793024534Mouse
1301435Trigq1_mtriglyceride QTL 1 (mouse)Not determined94442817478428262Mouse
1301051Eae9_msusceptibility to experimental allergic encephalomyelitis 9 (mouse)Not determined94942029863239852Mouse
5491195Mobq8_mmultigenic obesity QTL 8 (mouse)Not determined95936994693370128Mouse
1301049El4_mepilepsy 4 (mouse)Not determined94942029867151448Mouse
1301692Hts_mhypothermia sensitivity (mouse)Not determined93251117266511421Mouse
1558968Tbdr1_mbody temperature response to dietary restriction, QTL 1 (mouse)Not determined93503447869034599Mouse
4141071Ath29_matherosclerosis 29 (mouse)Not determined94041959474607925Mouse
4141323Ptnu3_mproteinuria 3 (mouse)Not determined93288970266889836Mouse
1301287Feml2_mfemur length in high growth mice 2 (mouse)Not determined95750728363207282Mouse
11532696Sluc39c_msusceptibility to lung cancer 39c (mouse)92558748559587581Mouse
1302180Actd4_mactivity-distance traveled 4 (mouse)Not determined93243456366434857Mouse
11532695Sluc39b_msusceptibility to lung cancer 39b (mouse)92558748559587581Mouse
1301803Stheal9_msoft tissue heal 9 (mouse)Not determined95902438793024534Mouse
11532694Sluc39a_msusceptibility to lung cancer 39a (mouse)92558748559587581Mouse
13208563Bmiq8_mbody mass index QTL 8 (mouse)92491129668907282Mouse
4141572Ntta3_mneurotensin transcript abundance 3 (mouse)Not determined4659767165831177Mouse
1301549Bbaa9_mB.burgdorferi-associated arthritis 9 (mouse)Not determined95780504771481754Mouse
1300563Pgia5_mproteoglycan induced arthritis 5 (mouse)Not determined94883105682831177Mouse
13525007Lfhrvq1_mlow frequency time index heart rate varaiblity, QTL 1 (mouse)95878431868556008Mouse
10043867Mtbcq9_mmultiple trait body composition QTL 9 (mouse)Not determined92679642160796552Mouse
1301456Adip5_madiposity 5 (mouse)Not determined95936994693370128Mouse
1301972Cocrb8_mcocaine related behavior 8 (mouse)Not determined93503447869034599Mouse
10043987Stheal13_msoft tissue heal 13 (mouse)Not determined92679642160796552Mouse
1558872Ibdq1_minflammatory bowel disease QTL 1 (mouse)Not determined93397884073439255Mouse
12738449Spcq2_msperm count QTL 2 (mouse)93939988573399885Mouse
1301184Bdln4_mbody length 4 (mouse)Not determined95015132084151448Mouse
4141676Neogq1_mneonatal growth QTL 1 (mouse)Not determined95780504786121973Mouse
1301702Brm1_mbrachyury modifier 1 (mouse)Not determined94080504774805204Mouse
1300932Hdlq17_mHDL QTL 17 (mouse)Not determined92679642160796552Mouse
10043971Obq32_mobesity QTL 32 (mouse)Not determined93781952871819528Mouse
10043847Hdlq89_mHDL QTL 89 (mouse)Not determined92929292963293072Mouse
10045639Heal28_mwound healing/regeneration 28 (mouse)Not determined94348071477480860Mouse
13525008Hrtiq1_mheart rate time index, QTL 1 (mouse)95242609868556008Mouse
1301965Vmbic5_mventral midbrain iron content 5 (mouse)Not determined95759149265831177Mouse
4141148Cq5_mcholesterol QTL 5 (mouse)Not determined93245242166452546Mouse
1300848Skull13_mskull morphology 13 (mouse)Not determined95936994693370128Mouse
4142042Alpq3_malcohol preference QTL 3 (mouse)Not determined93730619798701707Mouse
1301365Ap5q_malcohol preference 5 QTL (mouse)Not determined93005316464053277Mouse
1301241Renf1_mrenal failure 1 (mouse)Not determined95203447899792481Mouse
10043877Adip21_madiposity 21 (mouse)Not determined95643910890439255Mouse
10043878Adip20_madiposity 20 (mouse)Not determined92725119461251323Mouse
1300716Cd4ts4_mCD4 T cell subset 4 (mouse)Not determined94883105682831177Mouse

Markers in Region
Hexa  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map9BUniSTS
cM Map929.0UniSTS
RH134318  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38959,559,360 - 59,560,999UniSTSGRCm38
MGSCv37959,407,167 - 59,408,806UniSTSGRCm37
Celera956,786,488 - 56,788,127UniSTS
Cytogenetic Map9BUniSTS
cM Map929.0UniSTS


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001410424 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_010421 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_177070 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AA216951 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC123817 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH000835 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH006775 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK075895 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK075911 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK080777 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK144168 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK150444 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK151960 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK159091 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK159814 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK159890 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK160112 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK167013 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK168186 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK170903 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK179213 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK197174 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK204255 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK211327 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK213356 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK218113 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC010755 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466522 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U07630 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U07631 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X64331 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X79061 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X79062 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000026262   ⟹   ENSMUSP00000026262
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl959,446,823 - 59,472,392 (+)Ensembl
GRCm38.p6 Ensembl959,539,540 - 59,565,109 (+)Ensembl
RefSeq Acc Id: NM_001410424   ⟹   NP_001397353
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39959,446,966 - 59,472,392 (+)NCBI
RefSeq Acc Id: NM_010421   ⟹   NP_034551
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39959,446,966 - 59,472,392 (+)NCBI
GRCm38959,539,540 - 59,565,109 (+)NCBI
MGSCv37959,387,474 - 59,412,912 (+)RGD
Celera956,766,853 - 56,792,230 (+)RGD
cM Map9 ENTREZGENE
Sequence:
RefSeq Acc Id: NR_177070
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39959,446,966 - 59,472,392 (+)NCBI
RefSeq Acc Id: NP_034551   ⟸   NM_010421
- Peptide Label: isoform 1 preproprotein
- UniProtKB: Q64246 (UniProtKB/Swiss-Prot),   Q91XG3 (UniProtKB/Swiss-Prot),   P29416 (UniProtKB/Swiss-Prot),   Q3TW10 (UniProtKB/TrEMBL),   Q3U936 (UniProtKB/TrEMBL),   Q3UCP6 (UniProtKB/TrEMBL),   Q8BNS6 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000026262   ⟸   ENSMUST00000026262
RefSeq Acc Id: NP_001397353   ⟸   NM_001410424
- Peptide Label: isoform 2
Protein Domains
Beta-hexosaminidase eukaryotic type N-terminal   Glycoside hydrolase family 20 catalytic

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P29416-F1-model_v2 AlphaFold P29416 1-528 view protein structure

Promoters
RGD ID:6844661
Promoter ID:MM_KWN:57611
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000026262
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36959,387,146 - 59,387,712 (+)MPROMDB
RGD ID:8669840
Promoter ID:EPDNEW_M12950
Type:initiation region
Name:Hexa_1
Description:Mus musculus hexosaminidase A , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38959,539,683 - 59,539,743EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:96073 AgrOrtholog
Ensembl Genes ENSMUSG00000025232 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000026262 ENTREZGENE
  ENSMUST00000026262.8 UniProtKB/Swiss-Prot
Gene3D-CATH 3.30.379.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Glycosidases UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Beta_hexosaminidase_sua/sub UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Glyco_hydro_20_cat UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Glycoside_hydrolase_SF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Hex-like_dom2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HEX_eukaryotic_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:15211 UniProtKB/Swiss-Prot
MGD MGI:96073 ENTREZGENE
NCBI Gene 15211 ENTREZGENE
PANTHER BETA-HEXOSAMINIDASE SUBUNIT ALPHA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR22600 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Glyco_hydro_20 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Glycohydro_20b2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Hexa PhenoGen
PIRSF B-hxosamndse_ab_euk UniProtKB/TrEMBL, UniProtKB/Swiss-Prot
PRINTS GLHYDRLASE20 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE PROKAR_LIPOPROTEIN UniProtKB/TrEMBL
Superfamily-SCOP SSF51445 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF55545 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt HEXA_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q3THQ0_MOUSE UniProtKB/TrEMBL
  Q3TKF6_MOUSE UniProtKB/TrEMBL
  Q3TVI2_MOUSE UniProtKB/TrEMBL
  Q3TW10 ENTREZGENE, UniProtKB/TrEMBL
  Q3TXV7_MOUSE UniProtKB/TrEMBL
  Q3U936 ENTREZGENE, UniProtKB/TrEMBL
  Q3UCP6 ENTREZGENE, UniProtKB/TrEMBL
  Q64246 ENTREZGENE
  Q8BNS6 ENTREZGENE, UniProtKB/TrEMBL
  Q91XG3 ENTREZGENE
UniProt Secondary Q64246 UniProtKB/Swiss-Prot
  Q91XG3 UniProtKB/Swiss-Prot