Nr3c1 (nuclear receptor subfamily 3, group C, member 1) - Rat Genome Database

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Gene: Nr3c1 (nuclear receptor subfamily 3, group C, member 1) Mus musculus
Symbol: Nr3c1
Name: nuclear receptor subfamily 3, group C, member 1
RGD ID: 10691
Description: Enables several functions, including identical protein binding activity; nuclear glucocorticoid receptor activity; and protein kinase binding activity. Involved in several processes, including glial cell differentiation; intracellular glucocorticoid receptor signaling pathway; and positive regulation of miRNA transcription. Acts upstream of or within several processes, including maternal behavior; regulation of glucocorticoid biosynthetic process; and regulation of gluconeogenesis. Located in cytosol; membrane; and nucleus. Is expressed in several structures, including alimentary system; central nervous system; eye; genitourinary system; and leg muscle. Used to study primary hyperaldosteronism. Human ortholog(s) of this gene implicated in several diseases, including anorexia nervosa; lung disease (multiple); major depressive disorder; obesity; and renal cell carcinoma. Orthologous to human NR3C1 (nuclear receptor subfamily 3 group C member 1).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: G; glucocorticoid receptor; glucocorticoid receptor 1; glucocorticoid receptor subtype P; GR; Grl; Grl-1; Grl1; nuclear receptor subfamily 3 group C member 1
RGD Orthologs
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm391839,543,598 - 39,652,485 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1839,543,598 - 39,652,474 (-)EnsemblGRCm39 Ensembl
GRCm381839,410,545 - 39,519,421 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1839,410,545 - 39,519,421 (-)EnsemblGRCm38mm10GRCm38
MGSCv371839,570,199 - 39,646,899 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361839,537,961 - 39,615,820 (-)NCBIMGSCv36mm8
Celera1840,761,405 - 40,838,026 (-)NCBICelera
Cytogenetic Map18B3NCBI
cM Map1821.09NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations     Click to see Annotation Detail View
46, XX Disorders of Sex Development  (ISO)
anorexia nervosa  (ISO)
asthma  (ISO)
atrial fibrillation  (ISO)
bipolar disorder  (ISO)
brain ischemia  (ISO)
Burns  (ISO)
cataract  (ISO)
chronic obstructive pulmonary disease  (ISO)
cocaine abuse  (ISO)
Cocaine-Related Disorders  (ISO)
congestive heart failure  (ISO)
coronary artery disease  (ISO)
Cushing Syndrome  (IMP,ISO)
depressive disorder  (ISO)
Drug-Related Side Effects and Adverse Reactions  (ISO)
Edema  (ISO)
end stage renal disease  (ISO)
endometriosis  (ISO)
Endotoxemia  (ISO)
Experimental Autoimmune Encephalomyelitis  (IMP)
Experimental Diabetes Mellitus  (ISO)
familial adenomatous polyposis 1  (ISO)
fetal alcohol spectrum disorder  (ISO)
Fetal Growth Retardation  (ISO)
genetic disease  (ISO)
Glucocorticoid Receptor Deficiency  (ISO)
glucose metabolism disease  (ISO)
Hereditary Neoplastic Syndromes  (ISO)
hypertension  (IMP,ISO)
hypokalemia  (ISO)
interstitial lung disease  (ISO)
lipoid nephrosis  (ISO)
lung disease  (ISO)
lung non-small cell carcinoma  (ISO)
lupus nephritis  (IEP,ISO)
major depressive disorder  (ISO)
Malocclusion  (ISO)
mood disorder  (ISO)
muscular atrophy  (ISO)
nephrotic syndrome  (ISO)
nephrotic syndrome type 2  (ISO)
Neurodevelopmental Disorders  (ISO)
obesity  (ISO)
obstructive lung disease  (ISO)
obstructive sleep apnea  (ISO)
ocular hypertension  (ISO)
opioid abuse  (ISO)
Perennial Allergic Rhinitis  (ISO)
polycystic ovary syndrome  (ISO)
post-traumatic stress disorder  (ISO)
Prenatal Exposure Delayed Effects  (ISO)
primary biliary cholangitis  (ISO)
primary hyperaldosteronism  (IAGP)
prostate cancer  (ISO)
Prostatic Neoplasms  (ISO)
psychotic disorder  (ISO)
pulmonary sarcoidosis  (ISO)
renal cell carcinoma  (ISO)
rheumatoid arthritis  (ISO)
schizophrenia  (ISO)
Sepsis  (IEP,ISO)
sinusitis  (ISO)
status epilepticus  (ISO)
stress-related disorder  (ISO)
Stroke  (ISO)
Transplant Rejection  (ISO)
type 2 diabetes mellitus  (ISO)
uveitis  (ISO)
visual epilepsy  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-pilocarpine  (ISO)
(-)-anisomycin  (ISO)
(-)-epigallocatechin 3-gallate  (ISO)
(1->4)-beta-D-glucan  (EXP)
(3,4-dihydroxyphenyl)acetic acid  (EXP)
(S)-amphetamine  (EXP)
(S)-colchicine  (ISO)
(S)-nicotine  (EXP,ISO)
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane  (ISO)
1,2,3,4,7,8-Hexachlorodibenzofuran  (EXP)
1,2-dichloroethane  (EXP)
1,2-dimethylhydrazine  (EXP)
1,4-dithiothreitol  (ISO)
1-[2-(benzhydryloxy)ethyl]-4-(3-phenylpropyl)piperazine  (EXP)
1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile  (ISO)
1-bromopropane  (ISO)
1-chloro-2,4-dinitrobenzene  (ISO)
1-naphthyl isothiocyanate  (ISO)
11-deoxycorticosterone  (ISO)
11-deoxycortisol  (ISO)
15-deoxy-Delta(12,14)-prostaglandin J2  (EXP,ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17alpha-hydroxyprogesterone  (ISO)
17beta-estradiol  (ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,2',4,4'-tetrachlorobiphenyl  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3',4,4',5-Pentachlorobiphenyl  (ISO)
2,3,4,7,8-Pentachlorodibenzofuran  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-Trimethylbenzaldehyde  (ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2,4-dinitrotoluene  (ISO)
2,6-dinitrotoluene  (ISO)
2-(3,4-dimethoxyphenyl)-5-\{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino\}-2-(propan-2-yl)pentanenitrile  (EXP)
2-aminophenol  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3,4-Dimethylbenzaldehyde  (ISO)
3,4-methylenedioxymethamphetamine  (EXP)
3,5,6-trichloro-2-pyridinol  (EXP)
3,5,6-trichloropyridine-2-one  (EXP)
3,5-di-tert-Butyl-4-hydroxybenzaldehyde  (ISO)
3-methylcholanthrene  (ISO)
3-phenoxybenzoic acid  (EXP,ISO)
3alpha-hydroxy-5beta-pregnan-20-one  (EXP)
4'-hydroxydiclofenac  (ISO)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-(ethoxymethylene)-2-phenyloxazol-5-one  (ISO)
4-hydroxynon-2-enal  (EXP)
4-hydroxyphenyl retinamide  (EXP)
5-aza-2'-deoxycytidine  (ISO)
5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole  (ISO)
6-propyl-2-thiouracil  (ISO)
8-Br-cAMP  (ISO)
acetamide  (ISO)
acrolein  (ISO)
actinomycin D  (EXP)
aflatoxin B1  (ISO)
agomelatine  (EXP)
albuterol  (ISO)
aldehydo-D-glucose  (EXP)
aldosterone  (ISO)
all-trans-retinoic acid  (EXP,ISO)
alpha-pinene  (ISO)
amiodarone  (ISO)
amitriptyline  (EXP)
ammonium chloride  (ISO)
amphetamine  (ISO)
anthra[1,9-cd]pyrazol-6(2H)-one  (EXP)
antimycin A  (ISO)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsane  (EXP)
arsenic acid  (EXP)
arsenic atom  (EXP)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
atrazine  (ISO)
Aurin  (ISO)
avobenzone  (ISO)
aziridines  (EXP,ISO)
azoxystrobin  (ISO)
beclomethasone  (ISO)
benzbromarone  (ISO)
benzene  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
Benzoyl peroxide  (EXP)
betamethasone  (ISO)
betulin  (ISO)
bifenthrin  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol A diglycidyl ether  (EXP,ISO)
Bisphenol B  (ISO)
bisphenol F  (EXP,ISO)
bleomycin A2  (ISO)
budesonide  (ISO)
butachlor  (ISO)
butanal  (ISO)
Butylbenzyl phthalate  (EXP)
Butylparaben  (EXP,ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
carbamazepine  (EXP,ISO)
carbon nanotube  (EXP)
celecoxib  (ISO)
CGP 52608  (ISO)
chlorpromazine  (EXP)
choline  (EXP)
chromium(6+)  (ISO)
ciclopirox  (ISO)
cidofovir anhydrous  (ISO)
ciglitazone  (EXP)
cisplatin  (EXP,ISO)
citalopram  (ISO)
clodronic acid  (ISO)
clofibrate  (ISO)
clotrimazole  (ISO)
clozapine  (EXP)
cobalt atom  (ISO)
cocaine  (EXP,ISO)
colforsin daropate hydrochloride  (ISO)
compound 48/80  (EXP)
copper(II) sulfate  (ISO)
corticosterone  (EXP,ISO)
corticotropin  (ISO)
cortisol  (EXP,ISO)
cortisone  (ISO)
cortivazol  (ISO)
coumestrol  (ISO)
Cuprizon  (ISO)
curcumin  (ISO)
cycloheximide  (EXP,ISO)
cyclosporin A  (EXP,ISO)
Cyclosporin H  (EXP)
cyhalothrin  (ISO)
cypermethrin  (ISO)
D-glucose  (EXP)
daunorubicin  (ISO)
deflazacort  (ISO)
deguelin  (ISO)
dehydroepiandrosterone  (ISO)
desipramine  (ISO)
dexamethasone  (EXP,ISO)
Diallyl sulfide  (EXP)
diarsenic trioxide  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (EXP,ISO)
dichloromethane  (EXP)
diclofenac  (ISO)
Dicyclohexyl phthalate  (EXP)
diethyl hydrogen phosphate  (ISO)
diethyl phthalate  (EXP)
Diisodecyl phthalate  (EXP)
diisopropyl fluorophosphate  (ISO)
dioxygen  (ISO)
disodium selenite  (ISO)
dopamine  (EXP)
dorsomorphin  (ISO)
doxorubicin  (EXP,ISO)
elemental selenium  (ISO)
endrin  (EXP)
entinostat  (ISO)
enzacamene  (ISO)
ethanol  (EXP,ISO)
ethiofencarb  (ISO)
ethyl myristate  (ISO)
farglitazar  (ISO)
fenchone  (ISO)
fenpyroximate  (ISO)
fenvalerate  (ISO)
fludrocortisone  (ISO)
flumethasone  (ISO)
fluoranthene  (EXP)
fluoxetine  (EXP,ISO)
flutamide  (ISO)
fluticasone  (ISO)
folic acid  (EXP,ISO)
folpet  (EXP)
formaldehyde  (ISO)
formoterol fumarate  (ISO)
fulvestrant  (ISO)
fumonisin B1  (EXP)
furan  (ISO)
Fusarenone X  (EXP)
gamma-hexachlorocyclohexane  (ISO)
genistein  (ISO)
gentamycin  (ISO)
geraniol  (ISO)
ginsenoside Re  (ISO)
glafenine  (ISO)
glucose  (EXP)
hexadecanoic acid  (ISO)
homovanillic acid  (EXP)
hydralazine  (ISO)
hydrogen cyanide  (EXP)
hydrogen peroxide  (ISO)
ibuprofen  (EXP,ISO)
idazoxan  (ISO)
irinotecan  (ISO)
isoquinolines  (ISO)
ketoconazole  (EXP,ISO)
L-1,4-dithiothreitol  (ISO)
L-ascorbic acid  (ISO)
L-ethionine  (ISO)
L-methionine  (EXP)
lamotrigine  (ISO)
Laurolactam  (ISO)
lead diacetate  (EXP)
lead(0)  (EXP,ISO)
leflunomide  (ISO)
linuron  (ISO)
lipopolysaccharide  (EXP,ISO)
lithium atom  (EXP,ISO)
lithium chloride  (ISO)
lithium hydride  (EXP,ISO)
LY 379268  (ISO)
medroxyprogesterone acetate  (ISO)
melatonin  (EXP,ISO)
menadione  (ISO)
mercury dibromide  (ISO)
mercury dichloride  (ISO)
metformin  (ISO)
methamphetamine  (EXP,ISO)
methapyrilene  (ISO)
methotrexate  (ISO)
methoxychlor  (ISO)
methylmercury chloride  (ISO)
methylparaben  (EXP)
methylprednisolone aceponate  (ISO)
methylseleninic acid  (ISO)
methyltestosterone  (ISO)
miconazole  (ISO)
mifepristone  (EXP,ISO)
mirex  (ISO)
mitomycin C  (EXP)
mitoxantrone  (ISO)
molybdate  (ISO)
mometasone furoate  (ISO)
Monobutylphthalate  (ISO)
morphine  (ISO)
N,O-dimethyltyramine  (EXP)
N-acetyl-L-cysteine  (ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (ISO)
N-butylbenzenesulfonamide  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-nitrosodiethylamine  (ISO)
nefazodone  (ISO)
nickel dichloride  (ISO)
nickel sulfate  (ISO)
nicotine  (EXP,ISO)
nimesulide  (ISO)
nitric oxide  (ISO)
okadaic acid  (EXP)
omeprazole  (ISO)
onapristone  (ISO)
oxaliplatin  (ISO)
oxybenzone  (ISO)
ozone  (EXP,ISO)
paracetamol  (ISO)
paraquat  (ISO)
pararosaniline free base  (ISO)
parathion  (ISO)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
perfluorooctanoic acid  (ISO)
phenobarbital  (EXP,ISO)
Phenoxybenzamine  (EXP)
phenylbutazone  (ISO)
phenylephrine  (ISO)
phenylmercury acetate  (ISO)
phenytoin  (ISO)
phorbol 13-acetate 12-myristate  (EXP,ISO)
phorone  (ISO)
phosgene  (EXP)
pirinixic acid  (EXP,ISO)
Polygodial  (ISO)
potassium chloride  (ISO)
potassium chromate  (ISO)
potassium cyanide  (EXP)
prednisolone  (ISO)
prednisone  (EXP)
prednylidene  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
progesterone  (EXP,ISO)
promegestone  (ISO)
propiconazole  (EXP)
propylparaben  (ISO)
protoporphyrin  (ISO)
puromycin  (EXP)
pyrimidifen  (ISO)
quercetin  (EXP,ISO)
raloxifene  (ISO)
reactive oxygen species  (ISO)
reserpine  (ISO)
resmethrin  (ISO)
resveratrol  (EXP,ISO)
rifampicin  (ISO)
rimonabant  (EXP)
rotenone  (ISO)
S-methyl methanethiosulfonate  (ISO)
Salmeterol xinafoate  (ISO)
SB 203580  (ISO)
SB 431542  (ISO)
SCH 23390  (EXP)
selenium atom  (ISO)
selenous acid  (ISO)
senecionine  (ISO)
silicon dioxide  (EXP)
sirolimus  (EXP)
sodium arsenate  (EXP)
sodium arsenite  (EXP,ISO)
sodium dichromate  (EXP)
spiperone  (EXP)
spiroxamine  (ISO)
succimer  (EXP)
sulfasalazine  (ISO)
sulforaphane  (ISO)
sunitinib  (ISO)
tacrolimus hydrate  (EXP)
tamoxifen  (EXP,ISO)
Tanshinone I  (ISO)
tauroursodeoxycholic acid  (ISO)
tebufenpyrad  (ISO)
tenofovir disoproxil fumarate  (ISO)
terbutaline  (ISO)
teriflunomide  (ISO)
tert-butyl hydroperoxide  (ISO)
testosterone  (EXP,ISO)
tetrachloromethane  (EXP,ISO)
tetramethrin  (ISO)
tetraphene  (ISO)
thifluzamide  (ISO)
thioacetamide  (ISO)
thiram  (ISO)
thyroxine  (ISO)
titanium dioxide  (EXP)
tolcapone  (ISO)
tolterodine tartrate  (ISO)
tolylfluanid  (EXP,ISO)
topotecan  (ISO)
torcetrapib  (ISO)
triamcinolone  (ISO)
triamcinolone acetonide  (EXP,ISO)
tributyl phosphate  (ISO)
Tributyltin oxide  (ISO)
trichloroethene  (EXP,ISO)
trichostatin A  (ISO)
trifluoperazine  (EXP)
triphenyl phosphate  (ISO)
Triptolide  (ISO)
triptonide  (EXP)
Tris(2-ethylhexyl) phosphate  (ISO)
troglitazone  (ISO)
trovafloxacin  (ISO)
undecan-2-one  (ISO)
urethane  (ISO)
ursodeoxycholic acid  (ISO)
valdecoxib  (ISO)
valproic acid  (EXP,ISO)
venlafaxine hydrochloride  (ISO)
verapamil  (EXP)
vinclozolin  (ISO)
vorinostat  (ISO)
zearalenone  (ISO)
zidovudine  (ISO)
zinc atom  (ISO)
zinc oxide  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
adrenal gland development  (IMP)
androgen metabolic process  (ISO)
astrocyte differentiation  (IMP)
cellular response to dexamethasone stimulus  (ISO)
cellular response to glucocorticoid stimulus  (ISO)
cellular response to magnesium ion  (ISO)
cellular response to steroid hormone stimulus  (ISO)
cellular response to transforming growth factor beta stimulus  (ISO)
chromatin organization  (IEA)
chromatin remodeling  (ISO)
circadian rhythm  (ISO)
corticosteroid receptor signaling pathway  (ISO)
female pregnancy  (ISO)
gene expression  (IMP)
glucocorticoid mediated signaling pathway  (IEA)
glucocorticoid metabolic process  (IMP)
lung development  (ISO)
mammary gland duct morphogenesis  (IMP)
maternal behavior  (IGI)
microglia differentiation  (IMP)
motor behavior  (IMP)
muscle atrophy  (ISO)
negative regulation of apoptotic process  (ISO)
negative regulation of DNA-templated transcription  (ISO)
negative regulation of synaptic plasticity  (ISO)
negative regulation of transcription by RNA polymerase II  (ISO)
negative regulation of vascular permeability  (ISO)
neuroinflammatory response  (IMP)
nuclear receptor-mediated glucocorticoid signaling pathway  (IDA,IMP)
nuclear receptor-mediated steroid hormone signaling pathway  (IBA)
positive regulation of cell growth involved in cardiac muscle cell development  (ISO)
positive regulation of dendritic spine development  (ISO)
positive regulation of glucocorticoid receptor signaling pathway  (ISO)
positive regulation of glutamate secretion  (ISO)
positive regulation of miRNA transcription  (IDA,ISO)
positive regulation of neuron apoptotic process  (IGI)
positive regulation of transcription by RNA polymerase II  (ISO)
regulation of cell population proliferation  (ISO)
regulation of DNA-templated transcription  (IDA,ISO)
regulation of glucocorticoid biosynthetic process  (IMP)
regulation of gluconeogenesis  (IMP)
regulation of glucose metabolic process  (ISO)
regulation of transcription by RNA polymerase II  (IBA)
response to activity  (ISO)
response to arsenic-containing substance  (ISO)
response to calcium ion  (ISO)
response to corticosterone  (ISO)
response to dexamethasone  (ISO)
response to electrical stimulus  (ISO)
response to inactivity  (ISO)
response to insulin  (ISO)
response to mercury ion  (ISO)
synaptic transmission, glutamatergic  (IMP)
transcription initiation-coupled chromatin remodeling  (ISO)

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal adipose tissue distribution  (IAGP)
abnormal adrenal chromaffin cell morphology  (IAGP)
abnormal adrenal cortex morphology  (IAGP)
abnormal adrenal gland morphology  (IAGP)
abnormal adrenal gland zona fasciculata morphology  (IAGP)
abnormal adrenal gland zona glomerulosa morphology  (IAGP)
abnormal adrenal gland zona reticularis morphology  (IAGP)
abnormal alveolocapillary membrane morphology  (IAGP)
abnormal atrial thrombosis  (IAGP)
abnormal behavioral response to addictive substance  (IAGP)
abnormal blood-brain barrier function  (IAGP)
abnormal bone mineral density  (IAGP)
abnormal bone ossification  (IAGP)
abnormal branching involved in terminal bronchiole morphogenesis  (IAGP)
abnormal calcium ion homeostasis  (IAGP)
abnormal cecum morphology  (IAGP)
abnormal circulating corticosterone level  (IAGP)
abnormal fear/anxiety-related behavior  (IAGP)
abnormal heart echocardiography feature  (IAGP)
abnormal humoral immune response  (IAGP)
abnormal hypothalamus physiology  (IAGP)
abnormal interferon level  (IAGP)
abnormal interleukin level  (IAGP)
abnormal interleukin-6 secretion  (IAGP)
abnormal liver physiology  (IAGP)
abnormal lung development  (IAGP)
abnormal lung morphology  (IAGP)
abnormal mammary gland alveolus morphology  (IAGP)
abnormal mammary gland growth during pregnancy  (IAGP)
abnormal monocyte cell number  (IAGP)
abnormal myocardial fiber physiology  (IAGP)
abnormal nervous system electrophysiology  (IAGP)
abnormal osteoblast differentiation  (IAGP)
abnormal osteoblast physiology  (IAGP)
abnormal physiological response to xenobiotic  (IAGP)
abnormal pulmonary alveolus epithelial cell morphology  (IAGP)
abnormal pulmonary alveolus morphology  (IAGP)
abnormal respiratory system development  (IAGP)
abnormal response to CNS ischemic injury  (IAGP)
abnormal surfactant secretion  (IAGP)
abnormal thoracic cavity morphology  (IAGP)
abnormal thymocyte apoptosis  (IAGP)
abnormal tumor necrosis factor level  (IAGP)
absent adrenal medulla  (IAGP)
absent adrenergic chromaffin cells  (IAGP)
absent circulating adrenaline  (IAGP)
absent long-term depression  (IAGP)
atelectasis  (IAGP)
behavioral despair  (IAGP)
cardiac fibrosis  (IAGP)
cardiac hypertrophy  (IAGP)
cecum inflammation  (IAGP)
congestive heart failure  (IAGP)
cyanosis  (IAGP)
decreased adrenal gland zona fasciculata size  (IAGP)
decreased adrenaline level  (IAGP)
decreased anxiety-related response  (IAGP)
decreased B cell number  (IAGP)
decreased body length  (IAGP)
decreased body size  (IAGP)
decreased body weight  (IAGP)
decreased bone mineral density  (IAGP)
decreased bone trabecula number  (IAGP)
decreased cardiac muscle contractility  (IAGP)
decreased CD4-positive, alpha-beta T cell number  (IAGP)
decreased CD8-positive, alpha-beta T cell number  (IAGP)
decreased circulating adrenocorticotropin level  (IAGP)
decreased circulating corticosterone level  (IAGP)
decreased circulating noradrenaline level  (IAGP)
decreased circulating testosterone level  (IAGP)
decreased double-positive T cell number  (IAGP)
decreased erythroid progenitor cell number  (IAGP)
decreased locomotor activity  (IAGP)
decreased macrophage cell number  (IAGP)
decreased noradrenaline level  (IAGP)
decreased physiological sensitivity to xenobiotic  (IAGP)
decreased single-positive T cell number  (IAGP)
decreased survivor rate  (IAGP)
decreased susceptibility to neuronal excitotoxicity  (IAGP)
decreased T cell apoptosis  (IAGP)
decreased thymocyte apoptosis  (IAGP)
decreased type I pneumocyte number  (IAGP)
dilated heart left ventricle  (IAGP)
enlarged adrenal glands  (IAGP)
enlarged adrenocortical cell nuclei  (IAGP)
enlarged adrenocortical cells  (IAGP)
enlarged heart  (IAGP)
heart inflammation  (IAGP)
hypersecretion of corticotropin-releasing hormone  (IAGP)
impaired lung alveolus development  (IAGP)
increased adrenal gland zona fasciculata size  (IAGP)
increased adrenocorticotropin level  (IAGP)
increased body length  (IAGP)
increased bone trabecular spacing  (IAGP)
increased circulating adrenocorticotropin level  (IAGP)
increased circulating aldosterone level  (IAGP)
increased circulating angiotensinogen level  (IAGP)
increased circulating corticosterone level  (IAGP)
increased circulating glucocorticoid level  (IAGP)
increased heart left ventricle weight  (IAGP)
increased heart weight  (IAGP)
increased interleukin-1 beta secretion  (IAGP)
increased liver triglyceride level  (IAGP)
increased lung weight  (IAGP)
increased mean systemic arterial blood pressure  (IAGP)
increased myocardial fiber size  (IAGP)
increased renin activity  (IAGP)
increased susceptibility to endotoxin shock  (IAGP)
increased susceptibility to experimental autoimmune encephalomyelitis  (IAGP)
increased susceptibility to induced morbidity/mortality  (IAGP)
increased systemic arterial systolic blood pressure  (IAGP)
increased type II pneumocyte number  (IAGP)
lethality, complete penetrance  (IAGP)
neonatal lethality, complete penetrance  (IAGP)
neonatal lethality, incomplete penetrance  (IAGP)
no abnormal phenotype detected  (IAGP)
osteoporosis  (IAGP)
pathological neovascularization  (IAGP)
perinatal lethality, complete penetrance  (IAGP)
perinatal lethality, incomplete penetrance  (IAGP)
poor circulation  (IAGP)
postnatal lethality, complete penetrance  (IAGP)
premature death  (IAGP)
pulmonary hyperplasia  (IAGP)
respiratory distress  (IAGP)
respiratory failure  (IAGP)
small adrenal glands  (IAGP)
thick pulmonary interalveolar septum  (IAGP)
thick ventricular wall  (IAGP)
thin adrenal cortex  (IAGP)
thymus hypoplasia  (IAGP)

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