Fn1 (fibronectin 1) - Rat Genome Database

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Gene: Fn1 (fibronectin 1) Mus musculus
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Symbol: Fn1
Name: fibronectin 1
RGD ID: 10594
MGI Page MGI
Description: Enables peptidase activator activity and receptor ligand activity. Involved in negative regulation of monocyte activation and response to muscle activity. Acts upstream of or within several processes, including calcium-independent cell-matrix adhesion; cell-substrate junction assembly; and positive regulation of axon extension. Located in apical plasma membrane and basement membrane. Is active in extracellular space. Is expressed in several structures, including alimentary system; cardiovascular system; egg cylinder; embryo mesenchyme; and genitourinary system. Human ortholog(s) of this gene implicated in calcium oxalate nephrolithiasis; membranoproliferative glomerulonephritis; and spondylometaphyseal dysplasia corner fracture type. Orthologous to human FN1 (fibronectin 1).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: E330027I09; F; fibronectin; Fn; Fn-; Fn-1; MGC117493
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39171,624,632 - 71,692,439 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl171,624,679 - 71,692,359 (-)EnsemblGRCm39 Ensembl
GRCm38171,585,473 - 71,653,280 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl171,585,520 - 71,653,200 (-)EnsemblGRCm38mm10GRCm38
MGSCv37171,632,097 - 71,699,745 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36171,518,731 - 71,586,379 (-)NCBIMGSCv36mm8
Celera172,141,007 - 72,208,976 (-)NCBICelera
Cytogenetic Map1C3NCBI
cM Map136.05NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
acute kidney failure  (ISO)
Acute Otitis Media  (ISO)
Animal Mammary Neoplasms  (ISO)
aortic valve insufficiency  (ISO)
brain disease  (ISO)
Breast Neoplasms  (ISO)
calcium oxalate nephrolithiasis  (ISO)
carcinoma  (ISO)
Cardiac Fibrosis  (ISO)
Chronic Intermittent Hypoxia  (ISO)
chronic kidney disease  (ISO)
COVID-19  (ISO)
Crohn's disease  (ISO)
diabetes mellitus  (ISO)
diabetic angiopathy  (ISO)
Diabetic Nephropathies  (IEP,ISO)
end stage renal disease  (ISO)
Experimental Diabetes Mellitus  (ISO)
Experimental Liver Cirrhosis  (ISO)
Experimental Mammary Neoplasms  (ISO)
focal segmental glomerulosclerosis  (ISO)
genetic disease  (ISO)
glioblastoma  (ISO)
glomerulonephritis  (ISO)
Glomerulopathy with Giant Fibrillar Deposits  (ISO)
hypertension  (ISO)
IgA glomerulonephritis  (ISO)
iron deficiency anemia  (ISO)
Kidney Reperfusion Injury  (ISO)
Left Ventricular Hypertrophy  (ISO)
Liver Injury  (ISO)
Liver Reperfusion Injury  (ISO)
malignant mesothelioma  (ISO)
megacolon  (ISO)
membranoproliferative glomerulonephritis  (ISO)
myocardial infarction  (ISO)
Neoplasm Invasiveness  (ISO)
Neoplasm Metastasis  (ISO)
Neoplastic Cell Transformation  (ISO)
nephrotic syndrome  (ISO)
Neurodevelopmental Disorders  (ISO)
osteoarthritis  (ISO)
pulmonary fibrosis  (ISO)
renal cell carcinoma  (ISO)
renal fibrosis  (IEP)
renovascular hypertension  (ISO)
severe acute respiratory syndrome  (IEP)
Spinal Cord Injuries  (ISO)
spondyloepimetaphyseal dysplasia, Strudwick type  (ISO)
spondylometaphyseal dysplasia  (ISO)
spondylometaphyseal dysplasia corner fracture type  (ISO)
Spontaneous Abortions  (ISO)
Staphylococcal Pneumonia  (ISO)
Sturge-Weber syndrome  (ISO)
submandibular gland disease  (ISO)
ureteral obstruction  (ISO)
urinary bladder cancer  (ISO)
VACTERL association  (ISO)
X-linked Alport syndrome  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-catechin  (ISO)
(-)-demecolcine  (ISO)
(-)-epigallocatechin 3-gallate  (EXP)
(1->4)-beta-D-glucan  (EXP)
(R)-amygdalin  (EXP,ISO)
(R)-lipoic acid  (EXP,ISO)
(R)-noradrenaline  (ISO)
(R,R,R)-alpha-tocopherol  (ISO)
(S)-colchicine  (EXP)
(S)-nicotine  (EXP,ISO)
1,1-dichloroethene  (EXP)
1,2-dimethylhydrazine  (EXP)
1-(5-isoquinolinesulfonyl)-2-methylpiperazine  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (EXP,ISO)
17beta-estradiol 3-benzoate  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (EXP,ISO)
2,2',5,5'-tetrachlorobiphenyl  (EXP,ISO)
2,2,2-tetramine  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3-dimethoxynaphthalene-1,4-dione  (ISO)
2,4,6-trinitrobenzenesulfonic acid  (EXP)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (EXP)
2,4-dinitrotoluene  (ISO)
2-(3,4-dimethoxyphenyl)-5-\{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino\}-2-(propan-2-yl)pentanenitrile  (ISO)
2-acetamidofluorene  (ISO)
2-amino-2-deoxy-D-glucopyranose  (EXP,ISO)
2-bromohexadecanoic acid  (ISO)
2-naphthylamine  (ISO)
2-nitrofluorene  (ISO)
3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3-aminobenzamide  (ISO)
3-methyladenine  (ISO)
3-phenylprop-2-enal  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one  (ISO)
4-\{[(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)carbonyl]amino\}benzoic acid  (ISO)
4-hydroxyphenyl retinamide  (EXP)
4-phenylbutyric acid  (ISO)
5'-phosphopyridoxal-6-azobenzene-2,4-disulfonic acid  (EXP)
5-(2-methylpiperazine-1-sulfonyl)isoquinoline  (ISO)
5-aza-2'-deoxycytidine  (EXP)
5-chloro-7-iodoquinolin-8-ol  (ISO)
5-fluorouracil  (EXP)
6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide  (ISO)
6-propyl-2-thiouracil  (ISO)
7,12-dimethyltetraphene  (ISO)
8-Br-cAMP  (ISO)
9-cis-retinoic acid  (ISO)
acetaldehyde  (ISO)
acetamide  (ISO)
acetone  (ISO)
acetylsalicylic acid  (ISO)
aconitic acid  (EXP,ISO)
aconitine  (ISO)
acrolein  (ISO)
actinomycin D  (ISO)
adenine  (EXP,ISO)
afimoxifene  (ISO)
aflatoxin B1  (ISO)
albuterol  (ISO)
aldehydo-D-glucosamine  (EXP,ISO)
aldehydo-D-glucose  (EXP,ISO)
all-trans-retinoic acid  (EXP,ISO)
all-trans-retinol  (ISO)
allopurinol  (ISO)
alpha-hexachlorocyclohexane  (ISO)
alpha-pinene  (ISO)
alpha-Zearalanol  (ISO)
aluminium oxide  (ISO)
AM6545  (EXP)
ammonium chloride  (ISO)
Ammothamnine  (EXP)
amphetamine  (ISO)
andrographolide  (EXP)
anthra[1,9-cd]pyrazol-6(2H)-one  (EXP)
antirheumatic drug  (ISO)
apigenin  (ISO)
apocynin  (ISO)
arecoline  (EXP)
aripiprazole  (ISO)
aristolochic acid A  (ISO)
arsane  (EXP,ISO)
arsenic atom  (EXP,ISO)
arsenite(3-)  (EXP,ISO)
arsenous acid  (EXP,ISO)
artesunate  (ISO)
asbestos  (ISO)
Atractylodin  (EXP,ISO)
atrazine  (ISO)
bacitracin  (ISO)
baicalein  (ISO)
beclomethasone  (ISO)
benazepril  (ISO)
benzo[a]pyrene  (EXP,ISO)
berberine  (EXP,ISO)
beta-D-glucosamine  (EXP,ISO)
beta-lapachone  (ISO)
bexarotene  (ISO)
bezafibrate  (ISO)
bis(2-chloroethyl) sulfide  (EXP,ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
bisphenol F  (EXP,ISO)
bleomycin A2  (EXP,ISO)
boric acid  (EXP,ISO)
bosentan  (ISO)
bromobenzene  (ISO)
bromochloroacetic acid  (EXP)
brucine  (EXP,ISO)
bucladesine  (ISO)
butanal  (ISO)
butane  (ISO)
cadmium atom  (EXP,ISO)
cadmium dichloride  (EXP,ISO)
cadmium selenide  (ISO)
Calphostin C  (ISO)
carbamazepine  (ISO)
carbon nanotube  (EXP)
carbonyl sulfide  (ISO)
carvedilol  (ISO)
celastrol  (EXP,ISO)
CGP 52608  (ISO)
chelerythrine  (ISO)
chlordecone  (EXP)
chloroprene  (EXP)
chlorpyrifos  (EXP)
chromium(6+)  (ISO)
chrysin  (ISO)
cisplatin  (ISO)
clofibrate  (ISO)
clofibric acid  (ISO)
Clofop  (ISO)
cobalt atom  (ISO)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) chloride  (ISO)
cordycepin  (ISO)
crocidolite asbestos  (ISO)
curcumin  (EXP,ISO)
cyclosporin A  (EXP,ISO)
D-glucose  (EXP,ISO)
D-penicillamine  (ISO)
DDT  (ISO)
deoxynivalenol  (ISO)
desferrioxamine B  (ISO)
dexamethasone  (EXP,ISO)
dextran sulfate  (EXP)
diarsenic trioxide  (EXP,ISO)
diazinon  (ISO)
dibenz[a,h]anthracene  (EXP)
dibenziodolium  (ISO)
diclofenac  (EXP)
dicrotophos  (ISO)
diethylstilbestrol  (ISO)
dimethylarsinous acid  (ISO)
Diosbulbin B  (EXP)
dioxygen  (ISO)
diquat  (EXP)
diuron  (ISO)
dopamine  (ISO)
dorsomorphin  (ISO)
doxorubicin  (EXP,ISO)
ellagic acid  (ISO)
emodin  (ISO)
enalaprilat dihydrate  (EXP,ISO)
endosulfan  (ISO)
entinostat  (ISO)
eplerenone  (ISO)
eprosartan  (ISO)
esculetin  (ISO)
etacrynic acid  (ISO)
ethanol  (EXP,ISO)
farrerol  (ISO)
fasudil  (ISO)
fenamidone  (EXP)
fenofibrate  (EXP,ISO)
fenoldopam  (ISO)
flavonol  (ISO)
fluorescein 5-isothiocyanate  (ISO)
flutamide  (ISO)
folic acid  (EXP,ISO)
folpet  (EXP)
formaldehyde  (ISO)
formoterol fumarate  (ISO)
furan  (ISO)
gallic acid  (ISO)
gamma-hexachlorocyclohexane  (ISO)
gefitinib  (EXP)
geldanamycin  (ISO)
genistein  (EXP,ISO)
gentamycin  (ISO)
gestodene  (ISO)
gingerol  (ISO)
glafenine  (ISO)
glucose  (EXP,ISO)
glutathione  (ISO)
Glutathione ethyl ester  (ISO)
glyburide  (ISO)
glyphosate  (ISO)
graphene oxide  (ISO)
heptachlor  (ISO)
hexachlorobenzene  (ISO)
Honokiol  (EXP,ISO)
hydrogen peroxide  (ISO)
hydroquinone  (ISO)
indometacin  (ISO)
inulin  (EXP)
irinotecan  (ISO)
isoflavones  (ISO)
isopentane  (ISO)
isoprenaline  (EXP,ISO)
isotretinoin  (ISO)
ivermectin  (ISO)
JTE-013  (ISO)
kaempferol  (ISO)
ketamine  (ISO)
ketoconazole  (ISO)
L-ascorbic acid  (ISO)
Lasiocarpine  (ISO)
lead diacetate  (ISO)
lead(0)  (ISO)
linalool  (ISO)
lipoic acid  (EXP,ISO)
lipopolysaccharide  (ISO)
loliolide  (ISO)
losartan  (ISO)
LY-2157299  (EXP)
LY294002  (EXP,ISO)
manganese(II) chloride  (ISO)
mangiferin  (ISO)
manumycin A  (ISO)
masoprocol  (ISO)
medroxyprogesterone acetate  (ISO)
melamine  (ISO)
melatonin  (ISO)
melittin  (EXP)
mercury atom  (ISO)
mercury dibromide  (ISO)
mercury dichloride  (ISO)
mercury(0)  (ISO)
metformin  (EXP,ISO)
methamphetamine  (EXP)
methapyrilene  (ISO)
methotrexate  (ISO)
methoxychlor  (ISO)
methyl methanesulfonate  (ISO)
methylglyoxal  (ISO)
methylmercury chloride  (ISO)
methylparaben  (ISO)
methylseleninic acid  (ISO)
microcystin-LR  (EXP)
MK-2206  (EXP,ISO)
mono(2-ethylhexyl) phthalate  (EXP)
monocrotaline  (ISO)
morphine  (EXP)
myricetin  (ISO)
N(gamma)-nitro-L-arginine methyl ester  (EXP)
N,N-dimethylsphingosine  (ISO)
N-acetyl-L-cysteine  (ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (ISO)
N-methylformamide  (EXP)
N-nitrosodiethylamine  (ISO)
N-nitrosodimethylamine  (ISO)
nefazodone  (ISO)
nickel atom  (ISO)
nickel dichloride  (ISO)
nickel subsulfide  (ISO)
nickel sulfate  (ISO)
niclosamide  (EXP,ISO)
nicotine  (EXP,ISO)
nimesulide  (ISO)
nitrogen dioxide  (ISO)
notoginsenoside R1  (ISO)
obeticholic acid  (ISO)
ochratoxin A  (EXP,ISO)
olanzapine  (ISO)
organoselenium compound  (ISO)
orotic acid  (ISO)
ouabain  (ISO)
oxaliplatin  (ISO)
oxybenzone  (EXP)
ozone  (EXP,ISO)
Pachymic acid  (ISO)
paclitaxel  (ISO)
Paeonol  (ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP,ISO)
PCB138  (EXP,ISO)
pentane  (ISO)
pentane-2,3-dione  (ISO)
perfluorohexanesulfonic acid  (EXP)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
perfluorooctanoic acid  (ISO)
perindopril  (EXP)
phenobarbital  (EXP,ISO)
phenylephrine  (ISO)
phenylmercury acetate  (ISO)
phenytoin  (ISO)
PhIP  (ISO)
phorbol 13-acetate 12-myristate  (ISO)
picoxystrobin  (ISO)
piperonyl butoxide  (ISO)
pirfenidone  (EXP,ISO)
pirinixic acid  (EXP,ISO)
potassium dichromate  (ISO)
potassium iodide  (ISO)
prazosin  (ISO)
pregnenolone 16alpha-carbonitrile  (EXP,ISO)
progesterone  (ISO)
propene  (ISO)
propiconazole  (EXP)
Propiverine  (ISO)
propofol  (ISO)
propranolol  (ISO)
pyridoxal 5'-phosphate  (ISO)
pyrrolidine dithiocarbamate  (ISO)
pyrvinium  (ISO)
quartz  (EXP,ISO)
quercetin  (ISO)
radon atom  (ISO)
radon(0)  (ISO)
raloxifene  (EXP)
ramipril  (ISO)
reactive oxygen species  (ISO)
resveratrol  (EXP,ISO)
ridaforolimus  (ISO)
rosiglitazone  (ISO)
rosmarinic acid  (EXP)
rotenone  (ISO)
rutin  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
S-butyl-DL-homocysteine (S,R)-sulfoximine  (ISO)
Salidroside  (ISO)
salubrinal  (ISO)
SB 203580  (ISO)
SB 431542  (ISO)
serpentine asbestos  (EXP,ISO)
sevoflurane  (ISO)
sildenafil citrate  (EXP)
silicon dioxide  (EXP,ISO)
silver atom  (ISO)
silver(0)  (ISO)
simvastatin  (EXP,ISO)
Sinomenine  (ISO)
sodium arsenate  (EXP)
sodium arsenite  (EXP,ISO)
sodium dichromate  (ISO)
sodium dodecyl sulfate  (ISO)
sodium fluoride  (EXP)
sodium hydrogencarbonate  (ISO)
sodium hydroxide  (ISO)
sorafenib  (ISO)
sorbinil  (ISO)
sphingosine 1-phosphate  (ISO)
SR 144528  (EXP)
staurosporine  (ISO)
streptozocin  (EXP,ISO)
styrene  (ISO)
succimer  (ISO)
sunitinib  (ISO)
superoxide  (ISO)
tacrolimus hydrate  (EXP,ISO)
tamoxifen  (EXP,ISO)
Tanshinone I  (ISO)
tauroursodeoxycholic acid  (ISO)
telmisartan  (ISO)
teprenone  (EXP)
tert-butyl hydroperoxide  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP,ISO)
tetraethylenepentamine  (EXP,ISO)
tetramethylpyrazine  (EXP,ISO)
thapsigargin  (ISO)
thimerosal  (ISO)
thioacetamide  (EXP,ISO)
thiram  (ISO)
Tiron  (ISO)
titanium dioxide  (EXP,ISO)
toluene  (EXP,ISO)
topotecan  (ISO)
trandolapril  (ISO)
tributylstannane  (EXP)
trichostatin A  (ISO)
triclosan  (ISO)
triptonide  (EXP)
Triton X-100  (ISO)
troglitazone  (EXP,ISO)
troleandomycin  (ISO)
Tungsten carbide  (ISO)
valproic acid  (EXP,ISO)
vancomycin  (EXP,ISO)
venom  (ISO)
verapamil  (ISO)
vincaleukoblastine  (ISO)
vinclozolin  (ISO)
vitamin D  (EXP)
Y-27632  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)
zoledronic acid  (EXP,ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
acute-phase response  (IEA)
angiogenesis  (IEA)
biological process involved in interaction with symbiont  (IEA,ISO)
calcium-independent cell-matrix adhesion  (IDA)
cell adhesion  (IDA)
cell-matrix adhesion  (IBA,IDA,ISO)
cell-substrate junction assembly  (IBA,IDA)
cellular response to amyloid-beta  (ISO)
cellular response to angiotensin  (ISO)
cellular response to BMP stimulus  (ISO)
cellular response to glucose stimulus  (ISO)
cellular response to interleukin-1  (ISO)
cellular response to lipopolysaccharide  (ISO)
cellular response to mercury ion  (ISO)
cellular response to platelet-derived growth factor stimulus  (ISO)
cellular response to prostaglandin E stimulus  (ISO)
cellular response to transforming growth factor beta stimulus  (ISO)
cellular response to vascular endothelial growth factor stimulus  (ISO)
endodermal cell differentiation  (ISO)
extracellular matrix organization  (ISO)
glial cell migration  (ISO)
heart development  (IBA)
integrin activation  (IEA,ISO)
integrin-mediated signaling pathway  (IEA,ISO)
negative regulation of apoptotic process  (ISO)
negative regulation of collagen biosynthetic process  (ISO)
negative regulation of monocyte activation  (IDA,ISO)
negative regulation of transforming growth factor beta production  (IEA,ISO)
nervous system development  (IBA)
neural crest cell migration involved in autonomic nervous system development  (ISO)
peptide cross-linking  (ISO)
positive regulation of axon extension  (IDA)
positive regulation of cell migration  (ISO)
positive regulation of cell population proliferation  (ISO)
positive regulation of chemotaxis  (ISO)
positive regulation of fibroblast proliferation  (IEA,ISO)
positive regulation of gene expression  (IEA,ISO)
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction  (ISO)
positive regulation of substrate-dependent cell migration, cell attachment to substrate  (ISO)
regulation of cell shape  (IEA)
regulation of ERK1 and ERK2 cascade  (IEA,ISO)
regulation of protein phosphorylation  (ISO)
response to activity  (ISO)
response to glucocorticoid  (ISO)
response to iron ion  (ISO)
response to ischemia  (ISO)
response to muscle activity  (IDA)
response to ozone  (ISO)
response to xenobiotic stimulus  (ISO)
substrate adhesion-dependent cell spreading  (ISO)
wound healing  (IMP)

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal amnion morphology  (IAGP)
abnormal atrioventricular cushion morphology  (IAGP)
abnormal cardiac outflow tract development  (IAGP)
abnormal cholesterol homeostasis  (IAGP)
abnormal developmental patterning  (IAGP)
abnormal dorsal aorta morphology  (IAGP)
abnormal embryonic neuroepithelium morphology  (IAGP)
abnormal embryonic tissue morphology  (IAGP)
abnormal endocardium morphology  (IAGP)
abnormal extracellular matrix morphology  (IAGP)
abnormal extraembryonic tissue morphology  (IAGP)
abnormal gastrulation  (IAGP)
abnormal heart development  (IAGP)
abnormal heart morphology  (IAGP)
abnormal lateral plate mesoderm morphology  (IAGP)
abnormal liver physiology  (IAGP)
abnormal mesoderm development  (IAGP)
abnormal neural tube morphology  (IAGP)
abnormal notochord morphology  (IAGP)
abnormal placenta vasculature  (IAGP)
abnormal protein level  (IAGP)
abnormal response to injury  (IAGP)
abnormal rostral-caudal patterning of the somites  (IAGP)
abnormal vascular development  (IAGP)
abnormal vascular smooth muscle morphology  (IAGP)
abnormal vasculogenesis  (IAGP)
abnormal visceral yolk sac morphology  (IAGP)
abnormal vitelline vascular remodeling  (IAGP)
abnormal vitelline vasculature morphology  (IAGP)
absent limb buds  (IAGP)
absent notochord  (IAGP)
absent somites  (IAGP)
absent visceral yolk sac blood islands  (IAGP)
absent vitelline blood vessels  (IAGP)
anemia  (IAGP)
decreased cardiac jelly amount  (IAGP)
decreased circulating VLDL cholesterol level  (IAGP)
decreased embryo size  (IAGP)
decreased fibroblast proliferation  (IAGP)
decreased susceptibility to atherosclerosis  (IAGP)
decreased susceptibility to induced thrombosis  (IAGP)
disorganized yolk sac vascular plexus  (IAGP)
distended pericardium  (IAGP)
embryonic growth retardation  (IAGP)
embryonic lethality during organogenesis, complete penetrance  (IAGP)
embryonic lethality during organogenesis, incomplete penetrance  (IAGP)
embryonic lethality, complete penetrance  (IAGP)
failure of chorioallantoic fusion  (IAGP)
failure of initiation of embryo turning  (IAGP)
head mesenchyme hypoplasia  (IAGP)
hemorrhage  (IAGP)
impaired wound healing  (IAGP)
incomplete embryo turning  (IAGP)
incomplete somite formation  (IAGP)
increased carcinoma incidence  (IAGP)
increased cerebral infarct size  (IAGP)
increased neuron apoptosis  (IAGP)
increased susceptibility to ischemic brain injury  (IAGP)
increased tail bud apoptosis  (IAGP)
kinked neural tube  (IAGP)
kinked tail  (IAGP)
no abnormal phenotype detected  (IAGP)
premature death  (IAGP)
prenatal lethality, complete penetrance  (IAGP)
prenatal lethality, incomplete penetrance  (IAGP)
short rostral-caudal axis  (IAGP)
skin lesions  (IAGP)
spontaneous skin ulceration  (IAGP)
thick myocardium  (IAGP)
References

References - curated
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26. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
27. MGDs mouse GO annotations MGD data from the GO Consortium
28. MGD IEA MGD IEA
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30. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
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33. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
34. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
35. Mouse MP Annotation Import Pipeline RGD automated import pipeline
36. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
37. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
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Additional References at PubMed
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