Esr1 (estrogen receptor 1 (alpha)) - Rat Genome Database

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Gene: Esr1 (estrogen receptor 1 (alpha)) Mus musculus
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Symbol: Esr1
Name: estrogen receptor 1 (alpha)
RGD ID: 10551
MGI Page MGI
Description: Enables chromatin binding activity; nuclear receptor activity; and sequence-specific DNA binding activity. Involved in cellular response to estradiol stimulus and stem cell differentiation. Acts upstream of or within several processes, including mammary gland development; regulation of defense response; and reproductive structure development. Located in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; brain; genitourinary system; sensory organ; and skeleton. Used to study breast cancer. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); bone disease (multiple); breast cancer (multiple); type 2 diabetes mellitus; and vitiligo. Orthologous to human ESR1 (estrogen receptor 1).
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: AA420328; AU041214; C-terminally-truncated estrogen receptor alpha product-4; C-terminally-truncated estrogen receptor alpha product-5; C-terminally-truncated estrogen receptor alpha product-6; C-terminally-truncated estrogen receptor alpha product-7; E; ER; ER-; ER-alpha; ER[; ER[a]; ERa; ERalpha; Es; ESR; Estr; Estra; estradiol receptor; estrogen receptor; estrogen receptor alpha variant U1; estrogen receptor alpha variant U2; Nr; Nr3a1; nuclear receptor subfamily 3 group A member 1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
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Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39104,561,989 - 4,955,633 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl104,561,593 - 4,955,614 (+)EnsemblGRCm39 Ensembl
GRCm38104,611,989 - 5,005,633 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl104,611,593 - 5,005,614 (+)EnsemblGRCm38mm10GRCm38
MGSCv37105,342,780 - 5,734,495 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36105,342,780 - 5,734,495 (-)NCBIMGSCv36mm8
Celera104,553,702 - 4,949,051 (+)NCBICelera
Cytogenetic Map10A1NCBI
cM Map102.03NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model