(-)-epigallocatechin 3-gallate multiple interactions ISO EDNRB (Homo sapiens) 6480464 [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of EDNRB mRNA CTD PMID:22079256 (R)-noradrenaline multiple interactions ISO Ednrb (Rattus norvegicus) 6480464 [EDN1 protein binds to and results in increased activity of EDNRB protein] which results in decreased secretion of Norepinephrine and [EDN3 protein binds to and results in increased activity of EDNRB protein] which results in decreased secretion of Norepinephrine CTD PMID:16023617 (S)-colchicine increases expression ISO Ednrb (Rattus norvegicus) 6480464 Colchicine results in increased expression of EDNRB mRNA CTD PMID:20624997 (S)-nicotine increases activity ISO Ednrb (Rattus norvegicus) 6480464 Nicotine results in increased activity of EDNRB protein CTD PMID:21316381 1,2-dimethylhydrazine decreases expression EXP 6480464 1 and 2-Dimethylhydrazine results in decreased expression of EDNRB mRNA CTD PMID:22206623 17alpha-ethynylestradiol multiple interactions ISO EDNRB (Homo sapiens) 6480464 [Ethinyl Estradiol co-treated with Cholic Acids] affects the expression of EDNRB mRNA CTD PMID:27344345 17beta-estradiol multiple interactions ISO EDNRB (Homo sapiens) 6480464 [Estradiol co-treated with Progesterone] results in decreased expression of EDNRB mRNA CTD PMID:20660070 17beta-estradiol affects expression ISO Ednrb (Rattus norvegicus) 6480464 Estradiol affects the expression of EDNRB mRNA CTD PMID:32145629 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO EDNRB (Homo sapiens) 6480464 Tetrachlorodibenzodioxin results in decreased expression of EDNRB mRNA CTD PMID:20106945 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Ednrb (Rattus norvegicus) 6480464 Tetrachlorodibenzodioxin affects the expression of EDNRB mRNA CTD PMID:34747641 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO EDNRB (Homo sapiens) 6480464 Tetrachlorodibenzodioxin results in increased expression of EDNRB mRNA CTD PMID:25445724 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO EDNRB (Homo sapiens) 6480464 AHR gene SNP affects the reaction [Tetrachlorodibenzodioxin results in increased expression of EDNRB mRNA] CTD PMID:25445724 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO EDNRB (Homo sapiens) 6480464 Tetrachlorodibenzodioxin affects the expression of EDNRB mRNA CTD PMID:22298810 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of EDNRB mRNA CTD PMID:19465110 2-acetyl-1-alkyl-sn-glycero-3-phosphocholine multiple interactions ISO Ednrb (Rattus norvegicus) 6480464 EDNRB protein affects the reaction [Carbon Tetrachloride promotes the reaction [EDN1 protein results in increased abundance of Platelet Activating Factor]] and EDNRB protein affects the reaction [EDN1 protein results in increased abundance of Platelet Activating Factor] CTD PMID:18205269 2-butoxyethanol increases expression EXP 6480464 n-butoxyethanol results in increased expression of EDNRB mRNA CTD PMID:19812364 2-hydroxypropanoic acid decreases expression ISO EDNRB (Homo sapiens) 6480464 Lactic Acid results in decreased expression of EDNRB mRNA CTD PMID:30851411 3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine multiple interactions ISO Ednrb (Rattus norvegicus) 6480464 Methylprednisolone inhibits the reaction [Puromycin Aminonucleoside results in increased expression of EDNRB mRNA] CTD PMID:7756592 3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine increases expression ISO Ednrb (Rattus norvegicus) 6480464 Puromycin Aminonucleoside results in increased expression of EDNRB mRNA CTD PMID:7756592 3,4-methylenedioxymethamphetamine decreases expression EXP 6480464 N-Methyl-3 and 4-methylenedioxyamphetamine results in decreased expression of EDNRB mRNA CTD PMID:26251327 3,4-methylenedioxymethamphetamine decreases expression ISO Ednrb (Rattus norvegicus) 6480464 N-Methyl-3 and 4-methylenedioxyamphetamine results in decreased expression of EDNRB mRNA CTD PMID:30071829 3-\{1-[3-(dimethylamino)propyl]-1H-indol-3-yl\}-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione multiple interactions ISO Ednrb (Rattus norvegicus) 6480464 bisindolylmaleimide I inhibits the reaction [[EDN1 protein binds to and results in increased activity of EDNRB protein] which results in increased activity of NOS1 protein] and bisindolylmaleimide I inhibits the reaction [[EDN3 protein binds to and results in increased activity of EDNRB protein] which results in increased activity of NOS1 protein] CTD PMID:15245872 3-isobutyl-1-methyl-7H-xanthine multiple interactions ISO EDNRB (Homo sapiens) 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of EDNRB mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in increased expression of EDNRB mRNA CTD PMID:28628672 3H-1,2-dithiole-3-thione decreases expression ISO Ednrb (Rattus norvegicus) 6480464 1 and 2-dithiol-3-thione results in decreased expression of EDNRB mRNA CTD PMID:19162173 4,4'-sulfonyldiphenol affects methylation ISO EDNRB (Homo sapiens) 6480464 bis(4-hydroxyphenyl)sulfone affects the methylation of EDNRB gene CTD PMID:31601247 4-hydroxyphenyl retinamide increases expression EXP 6480464 Fenretinide results in increased expression of EDNRB mRNA CTD PMID:28973697 5-fluorouracil decreases expression ISO EDNRB (Homo sapiens) 6480464 Fluorouracil results in decreased expression of EDNRB mRNA CTD PMID:24737281 6-propyl-2-thiouracil decreases expression ISO Ednrb (Rattus norvegicus) 6480464 Propylthiouracil results in decreased expression of EDNRB mRNA CTD PMID:24780913 6-propyl-2-thiouracil increases expression ISO Ednrb (Rattus norvegicus) 6480464 Propylthiouracil results in increased expression of EDNRB mRNA CTD PMID:30047161 6alpha-methylprednisolone multiple interactions ISO Ednrb (Rattus norvegicus) 6480464 Methylprednisolone inhibits the reaction [Puromycin Aminonucleoside results in increased expression of EDNRB mRNA] CTD PMID:7756592 7,12-dimethyltetraphene decreases expression ISO Ednrb (Rattus norvegicus) 6480464 9 more ... CTD PMID:19480007 7-NITROINDAZOLE multiple interactions ISO Ednrb (Rattus norvegicus) 6480464 7-nitroindazole inhibits the reaction [[EDN1 protein binds to and results in increased activity of EDNRB protein] which results in increased activity of NOS1 protein] and 7-nitroindazole inhibits the reaction [[EDN3 protein binds to and results in increased activity of EDNRB protein] which results in increased activity of NOS1 protein] CTD PMID:15245872 8-bromo-3',5'-cyclic GMP multiple interactions ISO Ednrb (Rattus norvegicus) 6480464 8-bromocyclic GMP inhibits the reaction [[EDN1 protein binds to and results in increased activity of EDNRB protein] which results in decreased activity of TH protein] and 8-bromocyclic GMP inhibits the reaction [[EDN3 protein binds to and results in increased activity of EDNRB protein] which results in decreased activity of TH protein] CTD PMID:16023617 acadesine multiple interactions ISO Ednrb (Rattus norvegicus) 6480464 acadesine inhibits the reaction [Smoke results in increased expression of EDNRB protein] CTD PMID:36183783 acetamide increases expression ISO Ednrb (Rattus norvegicus) 6480464 acetamide results in increased expression of EDNRB mRNA CTD PMID:31881176 acetylsalicylic acid multiple interactions ISO EDNRB (Homo sapiens) 6480464 Aspirin inhibits the reaction [IL1B results in increased activity of EDNRB] CTD PMID:12126971 acrylamide decreases expression ISO Ednrb (Rattus norvegicus) 6480464 Acrylamide results in decreased expression of EDNRB mRNA CTD PMID:28959563 acrylamide decreases expression ISO EDNRB (Homo sapiens) 6480464 Acrylamide results in decreased expression of EDNRB mRNA CTD PMID:32763439 actinomycin D multiple interactions ISO Ednrb (Rattus norvegicus) 6480464 Dactinomycin inhibits the reaction [Cyclosporine results in increased expression of EDNRB mRNA] more ... CTD PMID:20561571 more ... all-trans-retinoic acid decreases expression ISO EDNRB (Homo sapiens) 6480464 Tretinoin results in decreased expression of EDNRB mRNA CTD PMID:21934132 amitrole increases expression ISO Ednrb (Rattus norvegicus) 6480464 Amitrole results in increased expression of EDNRB mRNA CTD PMID:30047161 ammonium chloride affects expression ISO Ednrb (Rattus norvegicus) 6480464 Ammonium Chloride affects the expression of EDNRB mRNA CTD PMID:16483693 amphotericin B increases expression ISO EDNRB (Homo sapiens) 6480464 Amphotericin B results in increased expression of EDNRB mRNA CTD PMID:20849824 angiotensin II increases expression ISO Ednrb (Rattus norvegicus) 6480464 Angiotensin II results in increased expression of EDNRB protein CTD PMID:15007106 anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions ISO Ednrb (Rattus norvegicus) 6480464 pyrazolanthrone inhibits the reaction [Dimethyl Sulfoxide results in increased expression of EDNRB mRNA] more ... CTD PMID:20561571 more ... arsane decreases expression EXP 6480464 Arsenic results in decreased expression of EDNRB mRNA CTD PMID:19654921 arsenic atom decreases expression EXP 6480464 Arsenic results in decreased expression of EDNRB mRNA CTD PMID:19654921 arsenous acid decreases expression ISO EDNRB (Homo sapiens) 6480464 Arsenic Trioxide results in decreased expression of EDNRB mRNA CTD PMID:26705709 arsenous acid increases expression ISO EDNRB (Homo sapiens) 6480464 Arsenic Trioxide results in increased expression of EDNRB mRNA alternative form CTD PMID:19128835 atrasentan multiple interactions ISO Ednrb (Rattus norvegicus) 6480464 Atrasentan inhibits the reaction [[19-oxo-11-deoxycorticosterone acetate co-treated with Potassium Chloride co-treated with Sodium Chloride] results in decreased expression of EDNRB mRNA] and Atrasentan inhibits the reaction [NG-Nitroarginine Methyl Ester results in decreased expression of EDNRB mRNA] CTD PMID:18823320 and PMID:34102242 belinostat multiple interactions ISO EDNRB (Homo sapiens) 6480464 [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of EDNRB mRNA CTD PMID:27188386 belinostat increases expression ISO EDNRB (Homo sapiens) 6480464 belinostat results in increased expression of EDNRB mRNA CTD PMID:26272509 benzo[a]pyrene decreases expression EXP 6480464 Benzo(a)pyrene results in decreased expression of EDNRB mRNA CTD PMID:22228805 and PMID:22610609 benzo[a]pyrene increases methylation ISO EDNRB (Homo sapiens) 6480464 Benzo(a)pyrene results in increased methylation of EDNRB exon CTD PMID:27901495 benzo[a]pyrene affects methylation ISO EDNRB (Homo sapiens) 6480464 Benzo(a)pyrene affects the methylation of EDNRB 5' UTR and Benzo(a)pyrene affects the methylation of EDNRB promoter CTD PMID:27901495 benzo[a]pyrene multiple interactions EXP 6480464 [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of EDNRB mRNA CTD PMID:27858113 benzo[a]pyrene increases expression EXP 6480464 Benzo(a)pyrene results in increased expression of EDNRB mRNA CTD PMID:19770486 more ... benzo[a]pyrene diol epoxide I affects expression ISO EDNRB (Homo sapiens) 6480464 7 more ... CTD PMID:20382639 benzo[b]fluoranthene decreases expression EXP 6480464 benzo(b)fluoranthene results in decreased expression of EDNRB mRNA CTD PMID:26377693 benzo[b]fluoranthene multiple interactions EXP 6480464 [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of EDNRB mRNA CTD PMID:27858113 bexarotene increases expression ISO Ednrb (Rattus norvegicus) 6480464 bexarotene results in increased expression of EDNRB mRNA CTD PMID:16648578 bis(2-ethylhexyl) phthalate increases expression ISO Ednrb (Rattus norvegicus) 6480464 Diethylhexyl Phthalate results in increased expression of EDNRB mRNA CTD PMID:20920545 bisphenol A increases expression ISO Ednrb (Rattus norvegicus) 6480464 bisphenol A results in increased expression of EDNRB mRNA CTD PMID:25181051 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of EDNRB mRNA CTD PMID:33221593 bisphenol A decreases expression ISO Ednrb (Rattus norvegicus) 6480464 bisphenol A results in decreased expression of EDNRB mRNA CTD PMID:30816183 more ... bisphenol A multiple interactions ISO EDNRB (Homo sapiens) 6480464 [bisphenol A co-treated with Fulvestrant] results in increased methylation of EDNRB gene and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of EDNRB mRNA CTD PMID:28628672 and PMID:31601247 bisphenol A increases methylation ISO EDNRB (Homo sapiens) 6480464 bisphenol A results in increased methylation of EDNRB gene and bisphenol A results in increased methylation of EDNRB promoter CTD PMID:27271280 and PMID:31601247 bisphenol F decreases expression EXP 6480464 bisphenol F results in decreased expression of EDNRB mRNA CTD PMID:30951980 bosentan multiple interactions ISO EDNRB (Homo sapiens) 6480464 bosentan binds to and results in decreased activity of EDNRB protein CTD PMID:16219361 cadmium atom multiple interactions ISO EDNRB (Homo sapiens) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of EDNRB mRNA CTD PMID:35301059 cadmium dichloride multiple interactions ISO EDNRB (Homo sapiens) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of EDNRB mRNA CTD PMID:35301059 calcitriol increases expression EXP 6480464 Calcitriol results in increased expression of EDNRB mRNA CTD PMID:12230499 carbon nanotube affects expression EXP 6480464 Nanotubes and Carbon affects the expression of EDNRB mRNA CTD PMID:23845593 carbon nanotube decreases expression EXP 6480464 Nanotubes more ... CTD PMID:25554681 and PMID:25620056 celecoxib multiple interactions ISO Ednrb (Rattus norvegicus) 6480464 Celecoxib inhibits the reaction [BQ 788 results in decreased expression of EDNRB protein] more ... CTD PMID:24462674 and PMID:25656942 CGP 52608 multiple interactions ISO EDNRB (Homo sapiens) 6480464 CGP 52608 promotes the reaction [RORA protein binds to EDNRB gene] CTD PMID:28238834 chlorambucil increases mutagenesis EXP 6480464 Chlorambucil results in increased mutagenesis of EDNRB gene CTD PMID:10517996 chloroprene increases expression ISO Ednrb (Rattus norvegicus) 6480464 Chloroprene results in increased expression of EDNRB mRNA CTD PMID:23125180 chlorpyrifos decreases expression ISO Ednrb (Rattus norvegicus) 6480464 Chlorpyrifos results in decreased expression of EDNRB mRNA CTD PMID:20691718 choline multiple interactions EXP 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of EDNRB mRNA CTD PMID:20938992 chromium atom multiple interactions EXP 6480464 LEPR gene mutant form promotes the reaction [[Niacin binds to Chromium] which results in increased expression of EDNRB mRNA] CTD PMID:16940432 chrysene multiple interactions EXP 6480464 [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of EDNRB mRNA CTD PMID:27858113 cisplatin increases expression ISO EDNRB (Homo sapiens) 6480464 Cisplatin results in increased expression of EDNRB mRNA CTD PMID:20849824 cocaine affects expression ISO Ednrb (Rattus norvegicus) 6480464 Cocaine affects the expression of EDNRB mRNA CTD PMID:20187946 copper atom increases expression ISO Ednrb (Rattus norvegicus) 6480464 Copper results in increased expression of EDNRB mRNA CTD PMID:30556269 copper(0) increases expression ISO Ednrb (Rattus norvegicus) 6480464 Copper results in increased expression of EDNRB mRNA CTD PMID:30556269 Cuprizon increases expression ISO Ednrb (Rattus norvegicus) 6480464 Cuprizone results in increased expression of EDNRB mRNA CTD PMID:26577399 and PMID:27523638 cycloheximide multiple interactions ISO Ednrb (Rattus norvegicus) 6480464 Cycloheximide inhibits the reaction [Dimethyl Sulfoxide results in increased expression of EDNRB mRNA] more ... CTD PMID:20561571 and PMID:20716444 cyclophosphamide increases expression ISO EDNRB (Homo sapiens) 6480464 Cyclophosphamide results in increased expression of EDNRB mRNA CTD PMID:20849824 cyclosporin A multiple interactions ISO Ednrb (Rattus norvegicus) 6480464 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [Cyclosporine results in increased expression of EDNRB mRNA] more ... CTD PMID:24462674 more ... cyclosporin A increases expression ISO Ednrb (Rattus norvegicus) 6480464 Cyclosporine results in increased expression of EDNRB mRNA and Cyclosporine results in increased expression of EDNRB protein CTD PMID:25772258 cyclosporin A decreases expression ISO Ednrb (Rattus norvegicus) 6480464 Cyclosporine results in decreased expression of EDNRB protein CTD PMID:24462674 and PMID:25656942 daunorubicin increases expression ISO Ednrb (Rattus norvegicus) 6480464 Daunorubicin results in increased expression of EDNRB protein CTD PMID:20888384 daunorubicin multiple interactions ISO Ednrb (Rattus norvegicus) 6480464 telmisartan promotes the reaction [Daunorubicin results in increased expression of EDNRB protein] CTD PMID:20888384 Deoxycorticosterone acetate multiple interactions ISO Ednrb (Rattus norvegicus) 6480464 [Desoxycorticosterone Acetate co-treated with Sodium Chloride] results in decreased expression of EDNRB mRNA and [Ozone co-treated with Oxygen] inhibits the reaction [[Desoxycorticosterone Acetate co-treated with Sodium Chloride] results in decreased expression of EDNRB mRNA] CTD PMID:26550192 dexamethasone multiple interactions ISO Ednrb (Rattus norvegicus) 6480464 Dexamethasone promotes the reaction [nitrofen results in increased expression of EDNRB mRNA] CTD PMID:10693666 dexamethasone multiple interactions ISO EDNRB (Homo sapiens) 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of EDNRB mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in increased expression of EDNRB mRNA CTD PMID:28628672 diarsenic trioxide decreases expression ISO EDNRB (Homo sapiens) 6480464 Arsenic Trioxide results in decreased expression of EDNRB mRNA CTD PMID:26705709 diarsenic trioxide increases expression ISO EDNRB (Homo sapiens) 6480464 Arsenic Trioxide results in increased expression of EDNRB mRNA alternative form CTD PMID:19128835 dibenz[a,h]anthracene decreases expression EXP 6480464 1 more ... CTD PMID:26377693 dibutyl phthalate increases expression EXP 6480464 Dibutyl Phthalate results in increased expression of EDNRB mRNA CTD PMID:17361019 and PMID:21266533 dimethyl sulfoxide increases expression ISO Ednrb (Rattus norvegicus) 6480464 Dimethyl Sulfoxide results in increased expression of EDNRB mRNA and Dimethyl Sulfoxide results in increased expression of EDNRB protein CTD PMID:20561571 dimethyl sulfoxide multiple interactions ISO Ednrb (Rattus norvegicus) 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Dimethyl Sulfoxide results in increased expression of EDNRB mRNA] more ... CTD PMID:20561571 dioxygen increases expression EXP 6480464 Oxygen deficiency results in increased expression of EDNRB mRNA more ... CTD PMID:21926265 and PMID:25203536 dioxygen decreases methylation ISO Ednrb (Rattus norvegicus) 6480464 Oxygen deficiency results in decreased methylation of EDNRB promoter CTD PMID:34478853 dioxygen increases expression ISO Ednrb (Rattus norvegicus) 6480464 Oxygen deficiency results in increased expression of EDNRB mRNA and Oxygen deficiency results in increased expression of EDNRB protein CTD PMID:34478853 dioxygen decreases expression ISO Ednrb (Rattus norvegicus) 6480464 Oxygen deficiency results in decreased expression of EDNRB protein CTD PMID:28985491 dioxygen multiple interactions ISO Ednrb (Rattus norvegicus) 6480464 [Oxygen deficiency co-treated with Blood Glucose deficiency co-treated with Particulate Matter] results in increased expression of EDNRB mRNA more ... CTD PMID:26550192 more ... dioxygen increases expression ISO EDNRB (Homo sapiens) 6480464 Oxygen deficiency results in increased expression of EDNRB mRNA CTD PMID:24236059 dioxygen multiple interactions EXP 6480464 [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of EDNRB mRNA more ... CTD PMID:21926265 and PMID:30529165 dorsomorphin multiple interactions ISO EDNRB (Homo sapiens) 6480464 [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 endosulfan increases expression ISO Ednrb (Rattus norvegicus) 6480464 Endosulfan results in increased expression of EDNRB mRNA CTD PMID:29391264 endosulfan decreases expression ISO Ednrb (Rattus norvegicus) 6480464 Endosulfan results in decreased expression of EDNRB mRNA CTD PMID:31464424 enrasentan multiple interactions ISO EDNRB (Homo sapiens) 6480464 enrasentan binds to and results in decreased activity of EDNRB protein CTD PMID:16219361 entinostat multiple interactions ISO EDNRB (Homo sapiens) 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of EDNRB mRNA CTD PMID:27188386 entinostat increases expression ISO EDNRB (Homo sapiens) 6480464 entinostat results in increased expression of EDNRB mRNA CTD PMID:26272509 ethanol decreases expression ISO Ednrb (Rattus norvegicus) 6480464 Ethanol results in decreased expression of EDNRB protein CTD PMID:16651399 ethanol increases expression ISO EDNRB (Homo sapiens) 6480464 Ethanol results in increased expression of EDNRB mRNA CTD PMID:31059573 ethanol increases expression EXP 6480464 Ethanol results in increased expression of EDNRB mRNA CTD PMID:30319688 etoposide decreases expression EXP 6480464 Etoposide results in decreased expression of EDNRB mRNA CTD PMID:25270620 fenoterol increases expression ISO EDNRB (Homo sapiens) 6480464 Fenoterol results in increased expression of EDNRB mRNA CTD PMID:16340002 folic acid multiple interactions EXP 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of EDNRB mRNA CTD PMID:20938992 folic acid decreases expression EXP 6480464 Folic Acid results in decreased expression of EDNRB mRNA CTD PMID:25629700 fulvestrant multiple interactions ISO EDNRB (Homo sapiens) 6480464 [bisphenol A co-treated with Fulvestrant] results in increased methylation of EDNRB gene CTD PMID:31601247 gefitinib multiple interactions EXP 6480464 gefitinib inhibits the reaction [TGFA protein results in decreased expression of EDNRB mRNA] CTD PMID:18424623 genistein decreases expression EXP 6480464 Genistein results in decreased expression of EDNRB mRNA CTD PMID:32186404 gentamycin multiple interactions ISO Ednrb (Rattus norvegicus) 6480464 [Gentamicins results in increased expression of EDNRB protein] which results in increased abundance of Nitrites CTD PMID:15200423 gentamycin increases expression ISO EDNRB (Homo sapiens) 6480464 Gentamicins results in increased expression of EDNRB mRNA CTD PMID:20849824 gentamycin increases expression ISO Ednrb (Rattus norvegicus) 6480464 Gentamicins results in increased expression of EDNRB protein CTD PMID:15200423 hydrogen cyanide increases expression EXP 6480464 Hydrogen Cyanide results in increased expression of EDNRB mRNA CTD PMID:33914522 Ile(5)-angiotensin II increases expression ISO Ednrb (Rattus norvegicus) 6480464 Angiotensin II results in increased expression of EDNRB protein CTD PMID:15007106 indometacin multiple interactions ISO EDNRB (Homo sapiens) 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of EDNRB mRNA more ... CTD PMID:12126971 and PMID:28628672 inulin multiple interactions EXP 6480464 [perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of EDNRB mRNA CTD PMID:36331819 isoprenaline multiple interactions ISO Ednrb (Rattus norvegicus) 6480464 CPU0213 inhibits the reaction [Isoproterenol results in increased expression of EDNRB mRNA] and natakalim inhibits the reaction [Isoproterenol results in increased expression of EDNRB protein] CTD PMID:18594475 and PMID:27174236 isoprenaline increases expression ISO Ednrb (Rattus norvegicus) 6480464 Isoproterenol results in increased expression of EDNRB mRNA and Isoproterenol results in increased expression of EDNRB protein CTD PMID:18594475 and PMID:27174236 isoquinoline-1,5-diol decreases expression ISO Ednrb (Rattus norvegicus) 6480464 1 and 5-dihydroxyisoquinoline results in decreased expression of EDNRB mRNA CTD PMID:12824290 ketoconazole increases expression ISO Ednrb (Rattus norvegicus) 6480464 Ketoconazole results in increased expression of EDNRB mRNA CTD PMID:36653537 L-ascorbic acid increases expression EXP 6480464 Ascorbic Acid results in increased expression of EDNRB mRNA CTD PMID:15305145 L-methionine multiple interactions EXP 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of EDNRB mRNA CTD PMID:20938992 lead diacetate increases expression ISO EDNRB (Homo sapiens) 6480464 lead acetate results in increased expression of EDNRB mRNA CTD PMID:22839698 malathion decreases expression ISO EDNRB (Homo sapiens) 6480464 Malathion results in decreased expression of EDNRB mRNA CTD PMID:37047231 mercury dibromide increases expression ISO EDNRB (Homo sapiens) 6480464 mercuric bromide results in increased expression of EDNRB mRNA CTD PMID:26272509 methotrexate affects expression EXP 6480464 Methotrexate affects the expression of EDNRB mRNA CTD PMID:18502557 methylmercury chloride increases expression ISO EDNRB (Homo sapiens) 6480464 methylmercuric chloride results in increased expression of EDNRB mRNA CTD PMID:34089799 methylseleninic acid increases expression ISO EDNRB (Homo sapiens) 6480464 methylselenic acid results in increased expression of EDNRB mRNA CTD PMID:18548127 mifepristone increases expression ISO EDNRB (Homo sapiens) 6480464 Mifepristone results in increased expression of EDNRB mRNA CTD PMID:17584828 MK-2206 increases expression ISO EDNRB (Homo sapiens) 6480464 MK 2206 results in increased expression of EDNRB protein CTD PMID:34398343 MK-2206 multiple interactions ISO EDNRB (Homo sapiens) 6480464 MK 2206 inhibits the reaction [RARRES2 protein results in decreased expression of EDNRB protein modified form] CTD PMID:34398343 N(gamma)-nitro-L-arginine methyl ester decreases expression ISO Ednrb (Rattus norvegicus) 6480464 NG-Nitroarginine Methyl Ester results in decreased expression of EDNRB mRNA CTD PMID:34102242 N(gamma)-nitro-L-arginine methyl ester multiple interactions ISO Ednrb (Rattus norvegicus) 6480464 Atrasentan inhibits the reaction [NG-Nitroarginine Methyl Ester results in decreased expression of EDNRB mRNA] CTD PMID:34102242 N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide multiple interactions ISO Ednrb (Rattus norvegicus) 6480464 N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [[EDN1 protein binds to and results in increased activity of EDNRB protein] which results in increased activity of NOS1 protein] and N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [[EDN3 protein binds to and results in increased activity of EDNRB protein] which results in increased activity of NOS1 protein] CTD PMID:15245872 N-[3,5-bis(trifluoromethyl)phenyl]-5-chloro-2-hydroxybenzamide multiple interactions ISO Ednrb (Rattus norvegicus) 6480464 N-(3 more ... CTD PMID:18718921 and PMID:22207076 N-ethyl-N-nitrosourea increases mutagenesis EXP 6480464 Ethylnitrosourea results in increased mutagenesis of EDNRB gene CTD PMID:17174358 and PMID:9475716 N-methyl-N-nitrosourea increases mutagenesis EXP 6480464 Methylnitrosourea results in increased mutagenesis of EDNRB gene CTD PMID:17174358 N-nitrosodiethylamine increases expression ISO Ednrb (Rattus norvegicus) 6480464 Diethylnitrosamine results in increased expression of EDNRB mRNA CTD PMID:19638242 nicotine increases activity ISO Ednrb (Rattus norvegicus) 6480464 Nicotine results in increased activity of EDNRB protein CTD PMID:21316381 nicotinic acid multiple interactions EXP 6480464 LEPR gene mutant form promotes the reaction [[Niacin binds to Chromium] which results in increased expression of EDNRB mRNA] CTD PMID:16940432 nimesulide multiple interactions ISO EDNRB (Homo sapiens) 6480464 nimesulide inhibits the reaction [IL1B results in increased activity of EDNRB] CTD PMID:12126971 nitric oxide multiple interactions ISO Ednrb (Rattus norvegicus) 6480464 [EDN1 protein results in increased activity of EDNRB protein] which results in increased abundance of Nitric Oxide CTD PMID:16380457 nitrites multiple interactions ISO Ednrb (Rattus norvegicus) 6480464 [Gentamicins results in increased expression of EDNRB protein] which results in increased abundance of Nitrites CTD PMID:15200423 nitrofen increases expression ISO Ednrb (Rattus norvegicus) 6480464 nitrofen results in increased expression of EDNRB mRNA and nitrofen results in increased expression of EDNRB protein CTD PMID:10693666 and PMID:19851775 nitrofen multiple interactions ISO Ednrb (Rattus norvegicus) 6480464 Dexamethasone promotes the reaction [nitrofen results in increased expression of EDNRB mRNA] CTD PMID:10693666 nitroprusside multiple interactions ISO Ednrb (Rattus norvegicus) 6480464 Nitroprusside inhibits the reaction [[EDN1 protein binds to and results in increased activity of EDNRB protein] which results in decreased activity of TH protein] and Nitroprusside inhibits the reaction [[EDN3 protein binds to and results in increased activity of EDNRB protein] which results in decreased activity of TH protein] CTD PMID:16023617 Nonylphenol increases expression ISO Ednrb (Rattus norvegicus) 6480464 nonylphenol results in increased expression of EDNRB mRNA CTD PMID:15620428 ozone multiple interactions ISO Ednrb (Rattus norvegicus) 6480464 [Ozone co-treated with Oxygen] inhibits the reaction [[Desoxycorticosterone Acetate co-treated with Sodium Chloride] results in decreased expression of EDNRB mRNA] and [Ozone co-treated with Vehicle Emissions] results in increased expression of EDNRB mRNA CTD PMID:20980218 and PMID:26550192 ozone multiple interactions EXP 6480464 [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased expression of EDNRB mRNA and [Air Pollutants results in increased abundance of Ozone] which results in decreased expression of EDNRB mRNA CTD PMID:27106289 and PMID:34911549 ozone increases expression EXP 6480464 Ozone results in increased expression of EDNRB mRNA CTD PMID:31626304 ozone increases expression ISO Ednrb (Rattus norvegicus) 6480464 Ozone results in increased expression of EDNRB mRNA CTD PMID:16081523 and PMID:20980218 panobinostat multiple interactions ISO EDNRB (Homo sapiens) 6480464 [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of EDNRB mRNA CTD PMID:27188386 panobinostat increases expression ISO EDNRB (Homo sapiens) 6480464 panobinostat results in increased expression of EDNRB mRNA CTD PMID:26272509 paracetamol affects expression EXP 6480464 Acetaminophen affects the expression of EDNRB mRNA CTD PMID:17562736 paracetamol decreases expression ISO EDNRB (Homo sapiens) 6480464 Acetaminophen results in decreased expression of EDNRB mRNA CTD PMID:29067470 paracetamol increases expression ISO EDNRB (Homo sapiens) 6480464 Acetaminophen results in increased expression of EDNRB mRNA CTD PMID:21420995 paricalcitol multiple interactions ISO EDNRB (Homo sapiens) 6480464 [Phosphorus co-treated with paricalcitol] affects the expression of EDNRB mRNA CTD PMID:17715259 perfluorooctane-1-sulfonic acid multiple interactions EXP 6480464 [perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of EDNRB mRNA CTD PMID:36331819 permethrin decreases expression ISO EDNRB (Homo sapiens) 6480464 Permethrin results in decreased expression of EDNRB mRNA CTD PMID:37047231 phenobarbital affects expression EXP 6480464 Phenobarbital affects the expression of EDNRB mRNA CTD PMID:23091169 phenylephrine increases expression ISO Ednrb (Rattus norvegicus) 6480464 Phenylephrine results in increased expression of EDNRB protein CTD PMID:15007106 phenylmercury acetate increases expression ISO EDNRB (Homo sapiens) 6480464 Phenylmercuric Acetate results in increased expression of EDNRB mRNA CTD PMID:26272509 phenylmercury acetate multiple interactions ISO EDNRB (Homo sapiens) 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of EDNRB mRNA CTD PMID:27188386 phosphoramidon increases expression ISO Ednrb (Rattus norvegicus) 6480464 phosphoramidon results in increased expression of EDNRB protein CTD PMID:15007106 phosphorus atom multiple interactions ISO EDNRB (Homo sapiens) 6480464 [Phosphorus co-treated with paricalcitol] affects the expression of EDNRB mRNA CTD PMID:17715259 phosphorus(.) multiple interactions ISO EDNRB (Homo sapiens) 6480464 [Phosphorus co-treated with paricalcitol] affects the expression of EDNRB mRNA CTD PMID:17715259 picrotoxin decreases expression ISO Ednrb (Rattus norvegicus) 6480464 Picrotoxin results in decreased expression of EDNRB mRNA CTD PMID:15170462 potassium chloride multiple interactions ISO Ednrb (Rattus norvegicus) 6480464 [19-oxo-11-deoxycorticosterone acetate co-treated with Potassium Chloride co-treated with Sodium Chloride] results in decreased expression of EDNRB mRNA and atrasentan inhibits the reaction [[19-oxo-11-deoxycorticosterone acetate co-treated with Potassium Chloride co-treated with Sodium Chloride] results in decreased expression of EDNRB mRNA] CTD PMID:18823320 potassium chromate multiple interactions ISO EDNRB (Homo sapiens) 6480464 [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of EDNRB mRNA CTD PMID:22079256 potassium chromate decreases expression ISO EDNRB (Homo sapiens) 6480464 potassium chromate(VI) results in decreased expression of EDNRB mRNA CTD PMID:22079256 potassium cyanide increases expression EXP 6480464 Potassium Cyanide results in increased expression of EDNRB mRNA CTD PMID:33914522 progesterone multiple interactions ISO EDNRB (Homo sapiens) 6480464 [Estradiol co-treated with Progesterone] results in decreased expression of EDNRB mRNA CTD PMID:20660070 progesterone increases expression ISO EDNRB (Homo sapiens) 6480464 Progesterone results in increased expression of EDNRB mRNA CTD PMID:21540246 quercetin increases expression ISO EDNRB (Homo sapiens) 6480464 Quercetin results in increased expression of EDNRB mRNA CTD PMID:15309432 quercetin affects expression ISO Ednrb (Rattus norvegicus) 6480464 Quercetin affects the expression of EDNRB mRNA CTD PMID:18178720 rac-lactic acid decreases expression ISO EDNRB (Homo sapiens) 6480464 Lactic Acid results in decreased expression of EDNRB mRNA CTD PMID:30851411 resveratrol multiple interactions ISO Ednrb (Rattus norvegicus) 6480464 Resveratrol inhibits the reaction [Smoke results in increased expression of EDNRB protein] and Resveratrol inhibits the reaction [Tobacco Smoke Pollution results in increased expression of EDNRB protein] CTD PMID:36183783 rofecoxib multiple interactions ISO EDNRB (Homo sapiens) 6480464 rofecoxib inhibits the reaction [IL1B results in increased activity of EDNRB] CTD PMID:12126971 SB 203580 multiple interactions ISO Ednrb (Rattus norvegicus) 6480464 SB 203580 inhibits the reaction [Cyclosporine results in increased expression of EDNRB mRNA] more ... CTD PMID:18718921 more ... SB 431542 multiple interactions ISO EDNRB (Homo sapiens) 6480464 [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 SB-239063 multiple interactions ISO Ednrb (Rattus norvegicus) 6480464 SB 239063 inhibits the reaction [Smoke results in increased expression of EDNRB mRNA] and SB 239063 inhibits the reaction [Smoke results in increased expression of EDNRB protein] CTD PMID:18718921 serpentine asbestos increases methylation ISO EDNRB (Homo sapiens) 6480464 Asbestos and Serpentine results in increased methylation of EDNRB 5' UTR CTD PMID:29523930 sodium arsenite increases expression ISO EDNRB (Homo sapiens) 6480464 sodium arsenite results in increased expression of EDNRB mRNA CTD PMID:20371982 sodium arsenite increases expression EXP 6480464 sodium arsenite results in increased expression of EDNRB mRNA CTD PMID:32068019 sodium arsenite multiple interactions ISO EDNRB (Homo sapiens) 6480464 sodium arsenite inhibits the reaction [EDN1 protein results in increased expression of EDNRB] CTD PMID:28470405 sodium chloride multiple interactions ISO Ednrb (Rattus norvegicus) 6480464 [19-oxo-11-deoxycorticosterone acetate co-treated with Potassium Chloride co-treated with Sodium Chloride] results in decreased expression of EDNRB mRNA more ... CTD PMID:18823320 and PMID:26550192 sorafenib increases expression ISO Ednrb (Rattus norvegicus) 6480464 Sorafenib results in increased expression of EDNRB mRNA and Sorafenib results in increased expression of EDNRB protein CTD PMID:33503445 staurosporine multiple interactions ISO Ednrb (Rattus norvegicus) 6480464 Staurosporine inhibits the reaction [Particulate Matter results in increased expression of EDNRB mRNA] and Staurosporine inhibits the reaction [Particulate Matter results in increased expression of EDNRB protein] CTD PMID:20561571 sulfadimethoxine increases expression ISO Ednrb (Rattus norvegicus) 6480464 Sulfadimethoxine results in increased expression of EDNRB mRNA CTD PMID:30047161 Tanshinone I multiple interactions ISO Ednrb (Rattus norvegicus) 6480464 tanshinone inhibits the reaction [Oxygen deficiency results in decreased expression of EDNRB protein] CTD PMID:28985491 telmisartan multiple interactions ISO Ednrb (Rattus norvegicus) 6480464 telmisartan promotes the reaction [Daunorubicin results in increased expression of EDNRB protein] CTD PMID:20888384 testosterone affects expression ISO Ednrb (Rattus norvegicus) 6480464 Testosterone affects the expression of EDNRB mRNA CTD PMID:12122504 and PMID:14616470 testosterone enanthate affects expression ISO EDNRB (Homo sapiens) 6480464 testosterone enanthate affects the expression of EDNRB mRNA CTD PMID:17440010 tetrachloromethane decreases expression EXP 6480464 Carbon Tetrachloride results in decreased expression of EDNRB mRNA CTD PMID:17484886 tetrachloromethane increases expression EXP 6480464 Carbon Tetrachloride results in increased expression of EDNRB mRNA CTD PMID:29987408 tetrachloromethane multiple interactions ISO Ednrb (Rattus norvegicus) 6480464 EDNRB protein affects the reaction [Carbon Tetrachloride promotes the reaction [EDN1 protein results in increased abundance of Platelet Activating Factor]] CTD PMID:18205269 tetrachloromethane increases expression ISO Ednrb (Rattus norvegicus) 6480464 Carbon Tetrachloride results in increased expression of EDNRB mRNA and Carbon Tetrachloride results in increased expression of EDNRB protein CTD PMID:12708965 more ... tetrachloromethane increases activity ISO Ednrb (Rattus norvegicus) 6480464 Carbon Tetrachloride results in increased activity of EDNRB protein CTD PMID:12873816 tetrachloromethane decreases expression ISO Ednrb (Rattus norvegicus) 6480464 Carbon Tetrachloride results in decreased expression of EDNRB mRNA CTD PMID:16644059 tetraphene multiple interactions EXP 6480464 [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of EDNRB mRNA CTD PMID:27858113 thimerosal decreases expression ISO EDNRB (Homo sapiens) 6480464 Thimerosal results in decreased expression of EDNRB mRNA CTD PMID:27188386 thioacetamide increases expression ISO Ednrb (Rattus norvegicus) 6480464 Thioacetamide results in increased expression of EDNRB mRNA CTD PMID:34492290 titanium dioxide decreases expression EXP 6480464 titanium dioxide results in decreased expression of EDNRB mRNA CTD PMID:23557971 titanium dioxide increases expression EXP 6480464 titanium dioxide results in increased expression of EDNRB mRNA CTD PMID:29264374 trichloroethene increases expression ISO Ednrb (Rattus norvegicus) 6480464 Trichloroethylene results in increased expression of EDNRB mRNA CTD PMID:33387578 trichostatin A increases expression ISO EDNRB (Homo sapiens) 6480464 trichostatin A results in increased expression of EDNRB mRNA CTD PMID:24935251 and PMID:26272509 trichostatin A multiple interactions ISO EDNRB (Homo sapiens) 6480464 [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of EDNRB mRNA CTD PMID:27188386 troglitazone decreases expression EXP 6480464 troglitazone results in decreased expression of EDNRB mRNA CTD PMID:28973697 U-73122 multiple interactions ISO Ednrb (Rattus norvegicus) 6480464 1-(6-((3-methoxyestra-1 more ... CTD PMID:15245872 udenafil decreases expression ISO Ednrb (Rattus norvegicus) 6480464 udenafil results in decreased expression of EDNRB CTD PMID:21366883 urethane multiple interactions EXP 6480464 Freund's Adjuvant inhibits the reaction [Urethane results in decreased expression of EDNRB mRNA] and IFNG protein inhibits the reaction [Urethane results in decreased expression of EDNRB mRNA] CTD PMID:12810352 urethane decreases expression EXP 6480464 Urethane results in decreased expression of EDNRB mRNA CTD PMID:12810352 valproic acid affects expression ISO EDNRB (Homo sapiens) 6480464 Valproic Acid affects the expression of EDNRB mRNA CTD PMID:25979313 valproic acid increases expression ISO EDNRB (Homo sapiens) 6480464 Valproic Acid results in increased expression of EDNRB mRNA CTD PMID:19101580 more ... valproic acid multiple interactions ISO EDNRB (Homo sapiens) 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of EDNRB mRNA CTD PMID:27188386 venlafaxine hydrochloride increases expression ISO Ednrb (Rattus norvegicus) 6480464 Venlafaxine Hydrochloride results in increased expression of EDNRB mRNA CTD PMID:25423262 vincaleukoblastine increases expression ISO Ednrb (Rattus norvegicus) 6480464 Vinblastine results in increased expression of EDNRB mRNA CTD PMID:20624997 vincristine increases expression ISO Ednrb (Rattus norvegicus) 6480464 Vincristine results in increased expression of EDNRB mRNA CTD PMID:20624997 vorinostat multiple interactions ISO EDNRB (Homo sapiens) 6480464 [NOG protein co-treated with Vorinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of EDNRB mRNA CTD PMID:27188386 vorinostat increases expression ISO EDNRB (Homo sapiens) 6480464 vorinostat results in increased expression of EDNRB mRNA CTD PMID:26272509 wedelolactone multiple interactions ISO Ednrb (Rattus norvegicus) 6480464 wedelolactone inhibits the reaction [Dimethyl Sulfoxide results in increased expression of EDNRB mRNA] more ... CTD PMID:18718921 more ... zinc atom decreases expression ISO Ednrb (Rattus norvegicus) 6480464 Zinc results in decreased expression of EDNRB mRNA CTD PMID:17074742 zinc sulfate decreases expression ISO Ednrb (Rattus norvegicus) 6480464 Zinc Sulfate results in decreased expression of EDNRB mRNA CTD PMID:17074742 zinc(0) decreases expression ISO Ednrb (Rattus norvegicus) 6480464 Zinc results in decreased expression of EDNRB mRNA CTD PMID:17074742
