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Gene: Prss57 (serine protease 57) Chinchilla lanigera

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Symbol:

Prss57

Name:

serine protease 57

RGD ID:

10388026

Description:

ENCODES a protein that exhibits heparin binding (ortholog); serine-type peptidase activity (ortholog); INVOLVED IN proteolysis (ortholog); ASSOCIATED WITH cerebral creatine deficiency syndrome (ortholog); COVID-19 (ortholog); cyclic hematopoiesis (ortholog); FOUND IN azurophil granule lumen (ortholog); extracellular space (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

protease, serine 57; protease, serine, 57

RGD Orthologs

Alliance Orthologs

More Info

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More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	PRSS57 (serine protease 57)	NCBI	Ortholog
Mus musculus (house mouse):	Prss57 (serine protease 57)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Prss57 (serine protease 57)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	PRSS57 (serine protease 57)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	PRSS57 (serine protease 57)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	PRSS57 (serine protease 57)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	PRSS57 (serine protease 57)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

ChiLan1.0 - Chinchilla ChiLan1.0 Assembly

Position:

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955495	7,067,844 - 7,077,048 (+)	NCBI	ChiLan1.0	ChiLan1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

cerebral creatine deficiency syndrome (ISO)

COVID-19 (ISO)

cyclic hematopoiesis (ISO)

long QT syndrome (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

proteolysis (ISO)

Cellular Component

azurophil granule lumen (ISO)

extracellular space (ISO)

Molecular Function

heparin binding (ISO)

serine-type peptidase activity (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Transitive Annotation Pipeline	Automated assignment of GO, PW and RDO ISO annotations across species

Genomics

Comparative Map Data

Prss57
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955495	7,067,844 - 7,077,048 (+)	NCBI	ChiLan1.0	ChiLan1.0

PRSS57
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	19	685,546 - 695,452 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	19	685,546 - 695,498 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	19	685,546 - 695,452 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	19	636,546 - 646,461 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	19	636,545 - 646,461	NCBI
Celera	19	120,996 - 132,062 (+)	NCBI		Celera
Cytogenetic Map	19	p13.3	NCBI
HuRef	19	455,352 - 465,453 (-)	NCBI		HuRef
CHM1_1	19	685,251 - 695,165 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	19	639,634 - 649,468 (-)	NCBI		T2T-CHM13v2.0

Prss57
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	10	79,617,308 - 79,630,523 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	10	79,617,308 - 79,626,795 (-)	Ensembl		GRCm39 Ensembl
GRCm38	10	79,781,474 - 79,794,684 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	10	79,781,474 - 79,790,961 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	10	79,244,219 - 79,251,730 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	10	79,244,219 - 79,251,730 (-)	NCBI		MGSCv36	mm8
Celera	10	80,796,169 - 80,803,685 (-)	NCBI		Celera
Cytogenetic Map	10	C1	NCBI
cM Map	10	39.72	NCBI

Prss57
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	7	10,563,477 - 10,573,617 (+)	NCBI		GRCr8
mRatBN7.2	7	9,915,667 - 9,922,996 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	9,917,484 - 9,922,922 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	7	12,798,509 - 12,803,869 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	7	14,676,590 - 14,681,950 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	7	12,535,791 - 12,541,268 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	7	12,798,310 - 12,804,668 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	12,798,868 - 12,804,283 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	7	12,968,017 - 12,975,388 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	7	11,431,197 - 11,436,541 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	7	11,431,196 - 11,436,541 (+)	NCBI
Celera	7	8,091,033 - 8,096,377 (+)	NCBI		Celera
Cytogenetic Map	7	q11	NCBI

PRSS57
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	20	5,009,782 - 5,027,487 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	19	4,246,843 - 4,265,570 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	19	440,415 - 452,535 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	19	650,617 - 652,304 (-)	NCBI	panpan1.1	PanPan1.1	panPan2

PRSS57
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	20	57,873,891 - 57,877,890 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	20	57,874,770 - 57,877,888 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	20	57,676,792 - 57,680,073 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	20	58,617,342 - 58,620,632 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	20	58,617,180 - 58,620,630 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	20	57,671,521 - 57,674,808 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	20	58,151,008 - 58,154,302 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	20	58,354,352 - 58,357,640 (+)	NCBI		UU_Cfam_GSD_1.0

PRSS57
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	77,650,879 - 77,655,712 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	2	77,649,741 - 77,657,627 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	78,325,996 - 78,327,174 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

PRSS57
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	6	443,859 - 449,539 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	6	444,098 - 449,152 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666081	8,505,941 - 8,511,532 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_013505061	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AGCD01062117	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

XM_013505061 ⟹ XP_013360515

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955495	7,067,844 - 7,077,048 (+)	NCBI

Sequence:

show sequence

ATGCTCGCCGCCCCGGGCCTGGGCCAGAGCCGGCGCCTTTCCCGGTGCCGCGTGCAGACGGTGC
GGACCGATGAGGACGCAGGAAACCCGGGGCCCCGGAGAGCGGGCCTGGGGAACGCGGAAGTCCA
GCTCCTGGGAGCCGGCATCGCTGCCACCCCACCCCACCCCCGGCCCGGGTCCCCAGCAGCCAGG
GGCGGGAAGAGCTGGGAGCGCGGAGGCCGGCTGAGGGCGCTGCGGGCGCAAAGGCCGGGGGCCT
CGGGGGTGAGCGGAGACCGGCCCGACGCCGCACGTGGGCGCCTGCGTTCATGCGGCCAGCGATG
CGGAGCGCGCACGGCCCTGGGAGAGGGGCTGGTGGAGGGAGCCCGGCGGACTCAGGCTTCACCT
GTGGCCACTGAAGAGCCGCAGCAGGACAGAGAGGCAGCGCCTGCCTTCCCTGGGCATGCAGACC
ACCACCCCGATCTCCCAGGAGACACCCGTGCCCTCGTCCCCAGCCCACTCCAAGATCCAGCAGT
GACTCAGGTGCTCTCTGCACCCCAGGACCCCAGAACGCTCACACCTGCTCCCCCTCCCGTCCGT
GCCAGCGCTGTCTCCATTAATCAGCTGCGCGGCCCTGCTCTGATCCTGCATGCAGCTGCCCCTC
CACAGGCACCTGGGGGGTCAAGATCGCTGGGCGCCAAGAGGGACCCCCAAGGAGACCTGGTGGT
ATGGGGGGGCTACACCTTGCACTCCTGGGGGCCCATACAGCAGGTTTTCAGCATCATGCTTCTT
GTCACACACCCAGATTACCAGCCCGTGACCCACGCCAAGGACATCTGCCTGCCGTGGGGAGCGC
GGGAGACCTTGACACTGTCCCCACAGCCTAATGGCTCTGCCATCTGGGGCCCAGCCATGGGGCT
ACTACGGCTGCTATGGAGAGACCCCAGGGCCCCTACAGCTGTGACCTGGTGCCAGGCTNNGGGG
CTAGTGTGAGACTTCAAGGACCCACCCCCTGGGCTGATGGAGGCCGAGGTCCGTGTGCTGGATC
TGGGTGTCTGCAGTAGCGCCTGGCTGCGCTCTGCTCTTAGAGCTGGCACTGCCGGAGGCAGGGT
TTTGCTCGGTGTAACATGCTCCTGCACACTTGCTTATGGTGGAAACAGACCCAGAAAGTGGACC
CTGACCTCGCCCAGACAGACTCTGGGGCACATGGTGTGCAGAAACCGCACCCACGGCCTCGTCT
CTTTCTCCGATCTCTGGTGTGGGGACCCTAAGTCCCTGGATGTGTACGCACAGGTGTCCCTCTT
CATGGCCTGGATCTGGGATGTCGTGCAGCCTGGTGACTCCCAGGCTGGGGCTGCGGGGCATCGC
CTCACGGCACAAAATTGAACGTGAAGCTGTCAGTTCAGATAGCGGTATGTCACAGCCGGGCCCC
AGAAGCCCAGGGCCTGGTGTCTGCAGGTGAGGGCAGCTGCTCCCAAATGAAAAGCCAGATCAAA
CCAGTGACACATTGGCTGACTAACCAGACACTGTGACAGCTTTATCCCAACAGGCTCCAGAACG
CCCCCAGTCCTGGCTCCTCAGCCTCTGAAATCCATGCCCCTTAGCCAGTGCCATCTCATGTGCC
TGTCACATTATCATCATTTTTTTTTTTTTTTAAT

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Protein Sequences


Protein RefSeqs	XP_013360515	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

XP_013360515 ⟸ XM_013505061

- Sequence:

show sequence

MLAAPGLGQSRRLSRCRVQTVRTDEDAGNPGPRRAGLGNAEVQLLGAGIAATPPHPRPGSPAAR
GGKSWERGGRLRALRAQRPGASGVSGDRPDAARGRLRSCGQRCGARTALGEGLVEGARRTQASP
VATEEPQQDREAAPAFPGHADHHPDLPGDTRALVPSPLQDPAVTQVLSAPQDPRTLTPAPPPVR
ASAVSINQLRGPALILHAAAPPQAPGGSRSLGAKRDPQGDLVVWGGYTLHSWGPIQQVFSIMLL
VTHPDYQPVTHAKDICLPWGARETLTLSPQPNGSAIWGPAMGLLRLLWRDPRAPTAVTWCQAXG
LVXDFKDPPPGLMEAEVRVLDLGVCSSAWLRSALRAGTAGGRVLLGVTCSCTLAYGGNRPRKWT
LTSPRQTLGHMVCRNRTHGLVSFSDLWCGDPKSLDVYAQVSLFMAWIWDVVQPGDSQAGAAGHR
LTAQN

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Additional Information

External Database Links

Database	Acc Id	Source(s)
NCBI Gene	Prss57	ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2018-01-23	Prss57	serine protease 57		protease, serine 57	Symbol and/or name change	5135510	APPROVED
2016-08-16	Prss57	protease, serine 57		protease, serine, 57	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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