Cd44 (CD44 antigen) - Rat Genome Database

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Gene: Cd44 (CD44 antigen) Mus musculus
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Symbol: Cd44
Name: CD44 antigen
RGD ID: 10310
MGI Page MGI
Description: Enables cargo receptor activity; hyaluronic acid binding activity; and type II transforming growth factor beta receptor binding activity. Contributes to cytokine binding activity and cytokine receptor activity. Involved in several processes, including hyaluronan catabolic process; negative regulation of T cell activation; and regulation of intracellular signal transduction. Acts upstream of or within several processes, including Wnt signaling pathway; morphogenesis of a branching epithelium; and wound healing involved in inflammatory response. Located in basolateral plasma membrane; external side of plasma membrane; and microvillus. Part of macrophage migration inhibitory factor receptor complex. Is expressed in several structures, including alimentary system; branchial arch; central nervous system; genitourinary system; and limb. Human ortholog(s) of this gene implicated in breast carcinoma (multiple); carcinoma (multiple); and prostate cancer. Orthologous to human CD44 (CD44 molecule (IN blood group)).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AU023126; AW121933; AW146109; ECMR-III; extracellular matrix receptor III; GP90 lymphocyte homing/adhesion receptor; HERM; HERMES; hermes antigen; HUTCH-I; hyaluronate receptor; Ly-2; Ly-24; lymphocyte antigen 24; Pgp; Pgp-1; PGP-I; phagocytic glycoprotein 1; phagocytic glycoprotein I
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392102,641,486 - 102,732,014 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2102,641,486 - 102,732,010 (-)EnsemblGRCm39 Ensembl
GRCm382102,811,141 - 102,901,669 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2102,811,141 - 102,901,665 (-)EnsemblGRCm38mm10GRCm38
MGSCv372102,651,298 - 102,741,822 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362102,611,980 - 102,702,504 (-)NCBIMGSCv36mm8
Celera2104,054,974 - 104,145,651 (-)NCBICelera
Cytogenetic Map2E2NCBI
cM Map254.13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-pilocarpine  (EXP)
(+)-schisandrin B  (ISO)
(-)-demecolcine  (ISO)
(-)-epigallocatechin 3-gallate  (EXP)
(S)-colchicine  (ISO)
(S)-nicotine  (EXP)
1,1-dichloroethene  (EXP)
1,2-dichloroethane  (EXP)
1,2-dimethylhydrazine  (EXP)
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine  (EXP)
1-naphthyl isothiocyanate  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-trinitrobenzenesulfonic acid  (EXP)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (EXP,ISO)
2,6-di-tert-butyl-4-methylphenol  (EXP)
2,6-dimethoxyphenol  (ISO)
2-(3,4-dimethoxyphenyl)-5-\{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino\}-2-(propan-2-yl)pentanenitrile  (EXP,ISO)
2-acetamidofluorene  (ISO)
2-hydroxypropanoic acid  (ISO)
2-methylcholine  (ISO)
2-nitroanisole  (ISO)
3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine  (ISO)
3,3',4,4'-tetrachlorobiphenyl  (ISO)
3,5-diethoxycarbonyl-1,4-dihydrocollidine  (EXP)
3-methylcholanthrene  (EXP)
4,4'-diaminodiphenylmethane  (EXP,ISO)
4,4'-sulfonyldiphenol  (EXP)
4-Amino-2-nitrophenol  (ISO)
4-hydroxynon-2-enal  (EXP)
4-vinylcyclohexene dioxide  (EXP)
5-aza-2'-deoxycytidine  (EXP,ISO)
5-fluorouracil  (ISO)
6-propyl-2-thiouracil  (ISO)
7,12-dimethyltetraphene  (EXP)
acetamide  (ISO)
acetylsalicylic acid  (ISO)
acrolein  (EXP)
acrylamide  (ISO)
Actein  (ISO)
afimoxifene  (ISO)
aflatoxin B1  (ISO)
albuterol  (ISO)
aldehydo-D-glucose  (EXP)
all-trans-retinoic acid  (EXP,ISO)
all-trans-retinol  (EXP)
allopurinol  (ISO)
amitrole  (ISO)
ammonium chloride  (ISO)
amphetamine  (ISO)
androgen antagonist  (ISO)
antirheumatic drug  (ISO)
Antrocin  (ISO)
aripiprazole  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
auramine O  (ISO)
Azaspiracid  (ISO)
bacitracin  (ISO)
bathocuproine disulfonic acid  (ISO)
beclomethasone  (ISO)
benzene  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (EXP)
benzoates  (ISO)
beryllium sulfate  (ISO)
beta-lapachone  (ISO)
bis(2-chloroethyl) sulfide  (EXP)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
Bisphenol B  (ISO)
bisphenol F  (EXP,ISO)
bleomycin A2  (EXP)
Butylparaben  (ISO)
butyric acid  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
calcium oxalate  (ISO)
cannabidiol  (ISO)
carbamazepine  (ISO)
carbon nanotube  (EXP)
carboplatin  (ISO)
carmustine  (ISO)
casticin  (ISO)
chlorogenic acid  (ISO)
chlorotoluron  (ISO)
chlorpromazine  (EXP,ISO)
choline  (EXP)
chromium(6+)  (EXP)
ciprofloxacin  (ISO)
cisplatin  (EXP,ISO)
cobalt dichloride  (ISO)
cocaine  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
coumarin  (ISO)
coumestrol  (ISO)
crizotinib  (ISO)
crocidolite asbestos  (ISO)
Cuprizon  (ISO)
curcumin  (ISO)
cycloheximide  (EXP)
cyclosporin A  (EXP,ISO)
cyproconazole  (ISO)
cytarabine  (ISO)
D-glucose  (EXP)
DDE  (ISO)
decabromodiphenyl ether  (ISO)
deguelin  (ISO)
dextran sulfate  (EXP)
diallyl trisulfide  (ISO)
diarsenic trioxide  (ISO)
diazinon  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (ISO)
dichlorine  (ISO)
diclofenac  (EXP)
Dictamnine  (ISO)
diethylstilbestrol  (ISO)
dimethylarsinous acid  (ISO)
dinophysistoxin 1  (ISO)
dioxygen  (EXP,ISO)
diquat  (EXP)
diuron  (ISO)
divanadium pentaoxide  (EXP,ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
elemental selenium  (ISO)
endosulfan  (ISO)
entinostat  (ISO)
enzacamene  (ISO)
enzyme inhibitor  (ISO)
epoxiconazole  (ISO)
ethanol  (ISO)
ethylene glycol  (ISO)
etodolac  (ISO)
etoposide  (ISO)
eugenol  (ISO)
fipronil  (ISO)
fisetin  (ISO)
folic acid  (EXP)
formaldehyde  (ISO)
formoterol fumarate  (ISO)
FR900359  (ISO)
fructose  (EXP)
fulvestrant  (EXP,ISO)
furan  (ISO)
furfural  (ISO)
gemcitabine  (ISO)
genistein  (EXP,ISO)
gentamycin  (ISO)
Gimeracil  (ISO)
glucose  (EXP)
glycidol  (ISO)
glycidyl methacrylate  (ISO)
glycine betaine  (ISO)
glyoxylic acid  (ISO)
glyphosate  (ISO)
graphite  (ISO)
GSK-J4  (ISO)
hexestrol  (ISO)
Honokiol  (EXP,ISO)
hyaluronic acid  (EXP,ISO)
hydrogen peroxide  (ISO)
indometacin  (ISO)
ionomycin  (ISO)
iron dichloride  (ISO)
iron(2+) sulfate (anhydrous)  (EXP)
iron(III) nitrilotriacetate  (ISO)
ivermectin  (ISO)
kaempferol  (EXP,ISO)
L-ascorbic acid  (EXP)
L-methionine  (EXP)
lamivudine  (ISO)
lapatinib  (ISO)
lead diacetate  (ISO)
lead(0)  (ISO)
linuron  (ISO)
lipopolysaccharide  (EXP,ISO)
lithium chloride  (ISO)
losartan  (ISO)
lovastatin  (ISO)
LY294002  (ISO)
manganese(II) chloride  (ISO)
melamine  (ISO)
menadione  (EXP)
mercury dibromide  (ISO)
mestranol  (ISO)
methapyrilene  (ISO)
methimazole  (ISO)
methoxychlor  (EXP)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
methylseleninic acid  (ISO)
mevalonic acid  (ISO)
microcystin-LR  (EXP)
Muraglitazar  (ISO)
N,N-bis(2-hydroxypropyl)nitrosamine  (ISO)
N-(6-acetamidohexyl)acetamide  (ISO)
N-butyl-N-(4-hydroxybutyl)nitrosamine  (ISO)
N-nitrosodiethylamine  (EXP,ISO)
N-nitrosodimethylamine  (ISO)
N-Nitrosopyrrolidine  (ISO)
nickel atom  (ISO)
nickel dichloride  (ISO)
nicotine  (EXP)
O-methyleugenol  (ISO)
ochratoxin A  (ISO)
okadaic acid  (ISO)
Osajin  (ISO)
oxalic acid  (ISO)
ozone  (EXP,ISO)
panobinostat  (ISO)
para-Cresidine  (ISO)
paracetamol  (EXP,ISO)
paraquat  (ISO)
phenethyl isothiocyanate  (ISO)
phenobarbital  (EXP,ISO)
phenylmercury acetate  (ISO)
phorbol 13-acetate 12-myristate  (EXP,ISO)
pirinixic acid  (EXP)
piroxicam  (ISO)
poly(I:C)  (ISO)
Pomiferin  (ISO)
proanthocyanidin  (ISO)
prochloraz  (ISO)
procymidone  (ISO)
progesterone  (EXP,ISO)
propiconazole  (EXP)
pyrrolidine dithiocarbamate  (ISO)
rac-lactic acid  (ISO)
raloxifene  (EXP,ISO)
reactive oxygen species  (ISO)
reparixin  (ISO)
resveratrol  (EXP,ISO)
rotenone  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
Salinomycin  (ISO)
SB 431542  (EXP,ISO)
selenium atom  (ISO)
serpentine asbestos  (EXP,ISO)
silicon dioxide  (EXP,ISO)
simvastatin  (ISO)
sodium arsenite  (EXP,ISO)
sodium chloride  (ISO)
sodium dichromate  (ISO)
Soman  (ISO)
stattic  (ISO)
succimer  (EXP,ISO)
sulfaphenazole  (ISO)
T-2 toxin  (ISO)
tacrolimus hydrate  (ISO)
tamibarotene  (ISO)
tamoxifen  (ISO)
temozolomide  (ISO)
Tesaglitazar  (ISO)
tetrachloromethane  (EXP,ISO)
thapsigargin  (ISO)
theaflavin  (EXP)
thioacetamide  (ISO)
thiram  (ISO)
thymoquinone  (ISO)
titanium dioxide  (EXP)
Tributyltin oxide  (ISO)
trichostatin A  (ISO)
trifluoperazine  (EXP)
trimethyltin  (EXP)
triphenyl phosphate  (ISO)
triphenylstannane  (ISO)
Triptolide  (ISO)
triptonide  (EXP)
ubiquinone-0  (ISO)
uracil  (ISO)
valproic acid  (ISO)
vancomycin  (ISO)
verapamil  (EXP,ISO)
vincaleukoblastine  (ISO)
vinclozolin  (ISO)
vincristine  (ISO)
vitamin E  (ISO)
vorinostat  (ISO)
zidovudine  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
anatomical structure morphogenesis  (IEA)
blood vessel maturation  (ISO)
branching involved in prostate gland morphogenesis  (IMP)
branching involved in ureteric bud morphogenesis  (IMP)
cartilage development  (ISO)
cell adhesion  (IBA,IEA,ISO)
cell migration  (ISO)
cellular response to fibroblast growth factor stimulus  (ISO)
cytokine-mediated signaling pathway  (IEA)
hyaluronan catabolic process  (IDA,IMP,ISO)
inflammatory response  (IBA)
macrophage fusion  (ISO)
monocyte aggregation  (ISO)
negative regulation of apoptotic process  (ISO)
negative regulation of CD4-positive, alpha-beta T cell proliferation  (IMP)
negative regulation of DNA damage response, signal transduction by p53 class mediator  (IMP,ISO)
negative regulation of inflammatory response  (IMP)
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator  (IMP,ISO)
negative regulation of mature B cell apoptotic process  (IDA)
negative regulation of regulatory T cell differentiation  (IMP)
neuron projection development  (ISO)
positive regulation of adaptive immune response  (NAS)
positive regulation of ERK1 and ERK2 cascade  (IBA,IMP,ISO)
positive regulation of gene expression  (IGI)
positive regulation of heterotypic cell-cell adhesion  (ISO)
positive regulation of kinase activity  (ISO)
positive regulation of monocyte aggregation  (ISO)
positive regulation of neutrophil apoptotic process  (ISO)
postsynapse organization  (ISO)
receptor-mediated endocytosis  (IDA,IMP)
regulation of cell growth  (ISO)
regulation of lamellipodium morphogenesis  (ISO,ISS)
regulation of leukocyte apoptotic process  (IEA)
regulation of modification of postsynaptic structure  (ISO)
response to nutrient levels  (ISO)
response to vitamin A  (ISO)
system development  (IEA)
T cell activation  (ISO)
Wnt signaling pathway  (IDA)
wound healing involved in inflammatory response  (IMP)
wound healing, spreading of cells  (ISO,ISS)

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal articular cartilage morphology  (IAGP)
abnormal CD4-positive, alpha beta T cell morphology  (IAGP)
abnormal CD4-positive, alpha-beta T cell physiology  (IAGP)
abnormal CD8-positive, alpha beta T cell morphology  (IAGP)
abnormal cell morphology  (IAGP)
abnormal cell physiology  (IAGP)
abnormal chemokine secretion  (IAGP)
abnormal circulating chemokine level  (IAGP)
abnormal circulating cytokine level  (IAGP)
abnormal definitive hematopoiesis  (IAGP)
abnormal digestive system physiology  (IAGP)
abnormal epidermal lamellar body morphology  (IAGP)
abnormal immune system physiology  (IAGP)
abnormal interleukin secretion  (IAGP)
abnormal involution of the mammary gland  (IAGP)
abnormal leukocyte adhesion  (IAGP)
abnormal leukocyte migration  (IAGP)
abnormal lipid level  (IAGP)
abnormal miniature excitatory postsynaptic currents  (IAGP)
abnormal miniature inhibitory postsynaptic currents  (IAGP)
abnormal mitochondrial crista morphology  (IAGP)
abnormal neutrophil physiology  (IAGP)
abnormal osteoclast differentiation  (IAGP)
abnormal osteoclast morphology  (IAGP)
abnormal phrenic nerve morphology  (IAGP)
abnormal physiological neovascularization  (IAGP)
abnormal response to cardiac infarction  (IAGP)
abnormal response to infection  (IAGP)
abnormal skin pigmentation  (IAGP)
abnormal T-helper 1 physiology  (IAGP)
abnormal T-helper 2 physiology  (IAGP)
abnormal uterus morphology  (IAGP)
abnormal vascular endothelial cell morphology  (IAGP)
abnormal vascular endothelial cell physiology  (IAGP)
abnormal vascular smooth muscle physiology  (IAGP)
abnormal vasculogenesis  (IAGP)
alopecia  (IEA)
autoimmune arthritis  (IAGP)
choroidal neovascularization  (IAGP)
decreased activation-induced cell death of T cells  (IAGP)
decreased acute inflammation  (IAGP)
decreased alpha-beta T cell number  (IEA)
decreased angiogenesis  (IAGP)
decreased blood urea nitrogen level  (IAGP)
decreased body weight  (IAGP)
decreased bone mass  (IAGP)
decreased CD4-positive, alpha-beta T cell number  (IEA)
decreased CD8-positive, alpha-beta T cell number  (IEA)
decreased central memory CD4-positive, alpha-beta T cell number  (IEA)
decreased central memory CD8 positive, alpha-beta T cell number  (IEA)
decreased cholesterol level  (IAGP)
decreased circulating creatinine level  (IAGP)
decreased circulating tumor necrosis factor level  (IAGP)
decreased compact bone thickness  (IAGP)
decreased effector memory CD4-positive, alpha-beta T cell number  (IEA)
decreased fibroblast proliferation  (IAGP)
decreased grip strength  (IAGP)
decreased intestinal adenoma incidence  (IAGP)
decreased mast cell histamine storage  (IAGP)
decreased mast cell number  (IAGP)
decreased metastatic potential  (IAGP)
decreased miniature excitatory postsynaptic current frequency  (IAGP)
decreased miniature inhibitory postsynaptic current frequency  (IAGP)
decreased myocardial infarct size  (IAGP)
decreased sensitivity to induced cell death  (IAGP)
decreased susceptibility to atherosclerosis  (IAGP)
decreased susceptibility to experimental autoimmune encephalomyelitis  (IAGP)
decreased susceptibility to induced arthritis  (IAGP)
decreased susceptibility to kidney reperfusion injury  (IAGP)
decreased susceptibility to type IV hypersensitivity reaction  (IAGP)
decreased T cell proliferation  (IAGP)
decreased trabecular bone mass  (IAGP)
decreased trabecular bone volume  (IAGP)
decreased transforming growth factor beta level  (IAGP)
decreased tumor growth/size  (IAGP)
delayed wound healing  (IAGP)
enhanced coordination  (IAGP)
hairless  (IAGP)
ileum inflammation  (IAGP)
impaired leukocyte tethering or rolling  (IAGP)
impaired macrophage phagocytosis  (IAGP)
impaired natural killer cell mediated cytotoxicity  (IAGP)
impaired neutrophil recruitment  (IAGP)
impaired skin barrier function  (IAGP)
impaired wound healing  (IAGP)
increased acute inflammation  (IAGP)
increased bone resorption  (IAGP)
increased circulating interferon-gamma level  (IAGP)
increased circulating interleukin-1 level  (IAGP)
increased circulating interleukin-2 level  (IAGP)
increased circulating interleukin-6 level  (IAGP)
increased circulating tumor necrosis factor level  (IAGP)
increased diameter of tibia  (IAGP)
increased enterocyte apoptosis  (IAGP)
increased interleukin-1 beta secretion  (IAGP)
increased interleukin-1 secretion  (IAGP)
increased interleukin-10 secretion  (IAGP)
increased interleukin-6 secretion  (IAGP)
increased intestinal adenoma incidence  (IAGP)
increased lymphoma incidence  (IAGP)
increased mean systemic arterial blood pressure  (IAGP)
increased metastatic potential  (IAGP)
increased miniature excitatory postsynaptic current amplitude  (IAGP)
increased mitochondrial size  (IAGP)
increased osteoclast cell number  (IAGP)
increased small intestinal crypt cell apoptosis  (IAGP)
increased susceptibility to induced arthritis  (IAGP)
increased susceptibility to induced morbidity/mortality  (IAGP)
increased susceptibility to parasitic infection  (IAGP)
increased tumor necrosis factor secretion  (IAGP)
increased tumor-free survival time  (IAGP)
joint swelling  (IAGP)
lethality, incomplete penetrance  (IAGP)
liver inflammation  (IAGP)
lung inflammation  (IAGP)
neonatal lethality, incomplete penetrance  (IAGP)
no abnormal phenotype detected  (IEA)
peritoneal inflammation  (IAGP)
premature death  (IAGP)
primary atelectasis  (IAGP)
respiratory distress  (IAGP)
short tibia  (IAGP)
thin epidermis  (IAGP)
weight loss  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. Diagnostic utility of CD44 standard, CD44v6, and CD44v3-10 expression in adenocarcinomas presenting in serous fluids. Afify A, etal., Appl Immunohistochem Mol Morphol. 2007 Dec;15(4):446-50.
2. Expression of hyaluronic acid and its receptors, CD44s and CD44v6, in normal, hyperplastic, and neoplastic endometrium. Afify AM, etal., Ann Diagn Pathol. 2005 Dec;9(6):312-8.
3. Hyaluronan expression following middle cerebral artery occlusion in the rat. Al Qteishat A, etal., Neuroreport. 2006 Jul 31;17(11):1111-4.
4. Wild-Type Isocitrate Dehydrogenase 1 Over-Expression is Related to Cancer Stem Cells Survival in Lung Adenocarcinoma. Al-Amodi HSAB, etal., Cancer Invest. 2018 Mar 16;36(3):185-189. doi: 10.1080/07357907.2018.1445262. Epub 2018 Mar 14.
5. Expression of CD44 isoforms in infiltrating lobular carcinoma of the breast. Berner HS and Nesland JM, Breast Cancer Res Treat. 2001 Jan;65(1):23-9.
6. Increased hyaluronan and CD44 expressions in intravenous leiomyomatosis. Chen MJ, etal., Acta Obstet Gynecol Scand. 2005 Apr;84(4):322-8.
7. Dynamics of hyaluronan, CD44, and inflammatory cells in the rat kidney after ischemia/reperfusion injury. Decleves AE, etal., Int J Mol Med. 2006 Jul;18(1):83-94.
8. Abnormal CD44 activation of hepatocytes with nonalcoholic fatty accumulation in rat hepatocarcinogenesis. Fang M, etal., World J Gastrointest Oncol. 2020 Jan 15;12(1):66-76. doi: 10.4251/wjgo.v12.i1.66.
9. Expression and prognostic value Of CD44 isoforms in nephroblastoma (Wilms tumor). Ghanem MA, etal., J Urol. 2002 Aug;168(2):681-6.
10. Cellular adhesion molecules in rat adjuvant arthritis. Halloran MM, etal., Arthritis Rheum. 1996 May;39(5):810-9.
11. Parallel up-regulation of FGF-2 and hyaluronan during development of cardiac hypertrophy in rat. Hellman U, etal., Cell Tissue Res. 2008 Jan 15;.
12. A role for CD44 in an antigen-induced murine model of pulmonary eosinophilia. Katoh S, etal., J Clin Invest. 2003 May;111(10):1563-70.
13. Modeling of hyperoxaluric calcium oxalate nephrolithiasis: experimental induction of hyperoxaluria by hydroxy-L-proline. Khan SR, etal., Kidney Int. 2006 Sep;70(5):914-23. Epub 2006 Jul 19.
14. Downregulation of BRG-1 repressed expression of CD44s in cervical neuroendocrine carcinoma and adenocarcinoma. Kuo KT, etal., Mod Pathol. 2006 Dec;19(12):1570-7. Epub 2006 Sep 22.
15. Ai zheng = Aizheng = Chinese journal of cancer Lian ZQ, etal., Ai Zheng. 2006 Oct;25(10):1291-5.
16. Prognostic role of CD44 cell adhesion molecule expression in primary and metastatic renal cell carcinoma: a clinicopathologic study of 125 cases. Lim SD, etal., Virchows Arch. 2008 Jan;452(1):49-55. Epub 2007 Nov 20.
17. Expression and significance of CD44s, CD44v6, and nm23 mRNA in human cancer. Liu YJ, etal., World J Gastroenterol. 2005 Nov 14;11(42):6601-6.
18. Expression and correlation of CD44v6, vascular endothelial growth factor, matrix metalloproteinase-2, and matrix metalloproteinase-9 in Krukenberg tumor. Lou G, etal., World J Gastroenterol. 2005 Aug 28;11(32):5032-6.
19. Expression and prognostic value of CD44 isoforms in transitional cell carcinoma of renal pelvis and ureter. Masuda M, etal., J Urol. 1999 Mar;161(3):805-8; discussion 808-9.
20. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
21. MGDs mouse GO annotations MGD data from the GO Consortium
22. MGD IEA MGD IEA
23. Expression of CD44 adhesion molecule in rat testis with ischemia/reperfusion injury. Moon C, etal., J Vet Med Sci. 2006 Jul;68(7):761-4.
24. In vivo evidence for the role of CD44s in promoting breast cancer metastasis to the liver. Ouhtit A, etal., Am J Pathol. 2007 Dec;171(6):2033-9. Epub 2007 Nov 8.
25. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
26. Mouse MP Annotation Import Pipeline RGD automated import pipeline
27. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
28. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
29. Effect of vitamin A on the CD44 expression in the small intestine of rats with obstructive jaundice. Sen M, etal., Eur Surg Res. 2006;38(3):347-52. Epub 2006 Jun 23.
30. [Clinical evaluation of BTAstat, NMP22, HA, survivin, CD44v6, vEGF and VUC in bladder cancer diagnosis] Sun Y, etal., Zhonghua Yi Xue Za Zhi. 2005 Sep 14;85(35):2507-12.
31. Prognostic significance of CD44, platelet-derived growth factor receptor alpha, and cyclooxygenase 2 expression in renal cell carcinoma. Tawfik OW, etal., Arch Pathol Lab Med. 2007 Feb;131(2):261-7.
32. Metallothioneins and zinc dysregulation contribute to neurodevelopmental damage in a model of perinatal viral infection. Williams BL, etal., Brain Pathol. 2006 Jan;16(1):1-14.
33. CD44 and PTGS2 methylation are independent prognostic markers for biochemical recurrence among prostate cancer patients with clinically localized disease. Woodson K, etal., Epigenetics. 2006 Oct-Dec;1(4):183-6.
34. Correlation of CD44v5 expression with invasiveness and prognosis in renal cell carcinoma. Wu ST, etal., J Formos Med Assoc. 2003 Apr;102(4):229-33.
35. Analyses of Bcl-2, Survivin, and CD44v6 expressions and human papillomavirus infection in cervical carcinomas. Yaqin M, etal., Scand J Infect Dis. 2007;39(5):441-8.
36. Glycoprotein CD44 expression in normal, hyperplasic and neoplastic endometrium. An immunohistochemical study including correlations with p53, steroid receptor status and proliferative indices (PCNA, MIB1). Zagorianakou N, etal., Eur J Gynaecol Oncol. 2003;24(6):500-4.
Additional References at PubMed
PMID:42904   PMID:1284074   PMID:1347918   PMID:1431091   PMID:1469058   PMID:1686571   PMID:1703543   PMID:1916820   PMID:2403559   PMID:2443580   PMID:2681416   PMID:2682651  
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PMID:9887098   PMID:10027409   PMID:10072077   PMID:10201888   PMID:10349636   PMID:10378887   PMID:10415067   PMID:10528194   PMID:10559399   PMID:10631184   PMID:10657301   PMID:10704459  
PMID:10725249   PMID:10814838   PMID:10825241   PMID:10848813   PMID:10859330   PMID:10922068   PMID:10926769   PMID:10943842   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11261780  
PMID:11278811   PMID:11342603   PMID:11560996   PMID:11581304   PMID:11592076   PMID:11713902   PMID:11762953   PMID:11825873   PMID:11862392   PMID:11932925   PMID:11935029   PMID:11956084  
PMID:11992408   PMID:12010794   PMID:12011075   PMID:12060392   PMID:12070778   PMID:12162503   PMID:12183839   PMID:12198773   PMID:12202399   PMID:12207337   PMID:12371152   PMID:12377945  
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Genomics

Comparative Map Data
Cd44
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392102,641,486 - 102,732,014 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2102,641,486 - 102,732,010 (-)EnsemblGRCm39 Ensembl
GRCm382102,811,141 - 102,901,669 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2102,811,141 - 102,901,665 (-)EnsemblGRCm38mm10GRCm38
MGSCv372102,651,298 - 102,741,822 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362102,611,980 - 102,702,504 (-)NCBIMGSCv36mm8
Celera2104,054,974 - 104,145,651 (-)NCBICelera
Cytogenetic Map2E2NCBI
cM Map254.13NCBI
CD44
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381135,139,171 - 35,232,402 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1135,138,882 - 35,232,402 (+)EnsemblGRCh38hg38GRCh38
GRCh371135,160,718 - 35,253,949 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361135,116,993 - 35,210,525 (+)NCBINCBI36Build 36hg18NCBI36
Build 341135,116,992 - 35,210,524NCBI
Celera1135,307,730 - 35,401,272 (+)NCBICelera
Cytogenetic Map11p13NCBI
HuRef1134,858,894 - 34,952,423 (+)NCBIHuRef
CHM1_11135,158,655 - 35,252,358 (+)NCBICHM1_1
T2T-CHM13v2.01135,277,234 - 35,370,499 (+)NCBIT2T-CHM13v2.0
Cd44
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83109,610,824 - 109,699,776 (-)NCBIGRCr8
GRCr8 Ensembl3109,612,054 - 109,699,424 (-)EnsemblGRCr8 Ensembl
mRatBN7.2389,155,850 - 89,244,615 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl389,157,058 - 89,244,620 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx392,655,896 - 92,743,295 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03101,254,921 - 101,342,322 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0399,079,238 - 99,166,676 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0392,695,083 - 92,783,820 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl392,696,313 - 92,783,658 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0399,338,248 - 99,426,188 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4388,022,962 - 88,110,352 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera388,236,830 - 88,324,125 (-)NCBICelera
RGSC_v3.1387,919,389 - 88,006,780 (-)NCBI
RH 3.4 Map3669.0RGD
RH 3.4 Map3656.5RGD
Cytogenetic Map3q32NCBI
Cd44
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495542211,106,061 - 11,189,951 (-)NCBIChiLan1.0ChiLan1.0
CD44
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2937,358,331 - 37,517,759 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11137,363,105 - 37,511,625 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01135,110,732 - 35,258,238 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11134,985,634 - 35,132,900 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1134,985,634 - 35,079,009 (+)Ensemblpanpan1.1panPan2
CD44
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11832,735,493 - 32,826,483 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1832,737,907 - 32,827,107 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1832,344,254 - 32,432,780 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01833,345,940 - 33,436,801 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1833,345,949 - 33,437,425 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11832,909,118 - 32,997,479 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01832,494,751 - 32,582,918 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01833,135,283 - 33,223,633 (-)NCBIUU_Cfam_GSD_1.0
Cd44
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494729,824,204 - 29,908,520 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049365332,949,026 - 3,033,166 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CD44
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl225,788,703 - 25,884,153 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1225,788,699 - 25,884,209 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2228,156,390 - 28,249,949 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CD44
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1130,039,854 - 30,132,646 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl130,039,749 - 30,132,416 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038127,154,654 - 127,246,994 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cd44
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476711,938,028 - 12,025,069 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476711,938,452 - 12,024,970 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Cd44
4489 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:2581
Count of miRNA genes:562
Interacting mature miRNAs:649
Transcripts:ENSMUST00000005218, ENSMUST00000060516, ENSMUST00000099673, ENSMUST00000111190, ENSMUST00000111191, ENSMUST00000111192, ENSMUST00000111194, ENSMUST00000111198, ENSMUST00000124624
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
13824983Vclq1_mcurvilinear velocity QTL 1 (mouse)261830344136841920Mouse
1301909Smdq2_msegregation of mitochondrial DNA QTL 2 (mouse)Not determined292778465126778607Mouse
4141236Hbnr5_mHeligmosomoides bakeri nematode resistance 5 (mouse)Not determined31214567105143570Mouse
1302174Dssc2_mdextran sodium sulfate induced colitis QTL2 (mouse)Not determined224224632148700377Mouse
1558915W3q1_mweight 3 weeks QTL 1 (mouse)Not determined220897778118894840Mouse
11532731Sluc31a_msusceptibility to lung cancer 31a (mouse)288015003122015170Mouse
27226761Feml18_mfemur length 18, 16 week (mouse)294230345154241920Mouse
1357454Kidq1_mkidney weight QTL 1 (mouse)Not determined220897778118894840Mouse
1357577Trmq3_mT cell ratio modifier QTL 3 (mouse)Not determined260520612119355518Mouse
1558966W10q9_mweight 10 weeks QTL 9 (mouse)Not determined220897778118894840Mouse
4141854T2dm2sa_mtype 2 diabetes mellitus 2 in SMXA RI mice (mouse)Not determined229307947148374934Mouse
12904935Edlmmq2_mextensor digitorum longus muscle mass QTL 2 (mouse)297210364131210364Mouse
1302071Fembrs1_mfemur breaking strength 1 (mouse)Not determined2100942930134943090Mouse
1302203Gvhd3_mgraft-versus host disease 3 (mouse)Not determined2100942930134943090Mouse
10412082Hylaq1_mHyperlocomotor activity related QTL 1 (mouse)Not determined284013198148667470Mouse
1357881Estoq1_membryo survival total QTL 1 (mouse)Not determined220897778118894840Mouse
5491197Mobq5_mmultigenic obesity QTL 5 (mouse)Not determined265269746162518926Mouse
1301948Elsgp3_melevated serum gp70 3 (mouse)Not determined268724269102724407Mouse
5491196Mobq6_mmultigenic obesity QTL 6 (mouse)Not determined285724269180896594Mouse
15092054Egrme5_mearly growth rate, maternal effect 5 (mouse)282190187118004745Mouse
4142223Femwf4_mfemur work to failure 4 (mouse)Not determined88143423122143570Mouse
4142088Parms1_mpatched associated RMS 1 (mouse)Not determined74524117114123532Mouse
4141448Mpaps1_mmicrophthalmia anophthalmia susceptibility 1 (mouse)Not determined97028557112115196Mouse
27226788Feml13_mfemur length 13, 10 week (mouse)2102630345159941920Mouse
12904954Gmmq2_mgastrocnemius muscle mass QTL 2 (mouse)297210364131210364Mouse
11038697Ltpr2d_mLeishmania tropica response 2d (mouse)286095716120095823Mouse
1301330Tbbmd2_mtotal body bone mineral density 2 (mouse)Not determined2100942930134943090Mouse
11038698Ltpr2c_mLeishmania tropica response 2c (mouse)286095716120095823Mouse
39128209Lwq14_mliver weight QTL 14 (mouse)220897778118894840Mouse
1558738W6q1_mweight 6 weeks QTL 1 (mouse)Not determined220897778118894840Mouse
11049568Lmr28c_mleishmaniasis resistance 28c (mouse)297123370131123532Mouse
11049569Lmr28d_mleishmaniasis resistance 28d (mouse)297123370131123532Mouse
11528549Sluc31_msusceptibility to lung cancer 31 (mouse)274524117129213005Mouse
4141802Ignpq1_mIgA nephropathy QTL 1 (mouse)Not determined2100824060134824269Mouse
1301834Bits1_mbitterness sensitivity 1 (mouse)Not determined287440643121440778Mouse
4141155Plast2b_mplasma plant sterol 2b (mouse)Not determined284013198148522175Mouse
1558901Skmw8_mskeletal muscle weight 8 (mouse)Not determined284008488118008593Mouse
1558899Egq1_mearly growth QTL 1 (mouse)Not determined220897778118894840Mouse
1357681Hrtq1_mheart weight QTL 1 (mouse)Not determined220897778118894840Mouse
1301109Dntcs2_mdental caries susceptibility 2 (mouse)Not determined240885493114910165Mouse
4141657Mohg1_mmodifier of hg 1 (mouse)Not determined276678758103095823Mouse
1300852Lmr14_mleishmaniasis resistance 14 (mouse)Not determined286095716120095823Mouse
1357436Splq1_mspleen weight QTL 1 (mouse)Not determined220897778118894840Mouse
1301882Etohc2_methanol consumption 2 (mouse)Not determined268724269102724407Mouse
1301374Cplaq7_mcircadian period of locomotor activity 7 (mouse)Not determined276421483110421651Mouse
10043894Bw22_mbody weight QTL 22 (mouse)Not determined280895334114895334Mouse
1301344Lith1_mlithogenic gene 1 (mouse)Not determined245347635145312647Mouse
11049565Lmr28g_mleishmaniasis resistance 28g (mouse)286095716120095823Mouse
1301098Cd8mts3_mCD8 memory T cell subset 3 (mouse)Not determined291089974125090104Mouse

Markers in Region
AW121933  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm382102,812,840 - 102,812,930UniSTSGRCm38
MGSCv372102,652,997 - 102,653,087UniSTSGRCm37
Celera2104,056,673 - 104,056,763UniSTS
Cytogenetic Map2E2UniSTS
cM Map256.0UniSTS
Whitehead/MRC_RH21395.17UniSTS
AW146109  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm382102,811,507 - 102,811,647UniSTSGRCm38
MGSCv372102,651,664 - 102,651,804UniSTSGRCm37
Celera2104,055,340 - 104,055,480UniSTS
Cytogenetic Map2E2UniSTS
cM Map256.0UniSTS
Whitehead/MRC_RH21395.17UniSTS
J05163  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm382102,814,049 - 102,814,132UniSTSGRCm38
MGSCv372102,654,206 - 102,654,289UniSTSGRCm37
Celera2104,057,882 - 104,057,965UniSTS
Cytogenetic Map2E2UniSTS
cM Map256.0UniSTS
Whitehead/MRC_RH21396.11UniSTS
PMC111028P1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm382102,814,222 - 102,814,314UniSTSGRCm38
MGSCv372102,654,379 - 102,654,471UniSTSGRCm37
Celera2104,058,055 - 104,058,147UniSTS
Cytogenetic Map2E2UniSTS
cM Map256.0UniSTS
Cd44  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm382102,814,139 - 102,814,297UniSTSGRCm38
MGSCv372102,654,296 - 102,654,454UniSTSGRCm37
Celera2104,057,972 - 104,058,130UniSTS
Cytogenetic Map2E2UniSTS
cM Map256.0UniSTS
Cd44  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map2E2UniSTS
cM Map256.0UniSTS
Cd44  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map2E2UniSTS
cM Map256.0UniSTS
Cd44  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map2E2UniSTS
cM Map256.0UniSTS
Cd44  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map2E2UniSTS
cM Map256.0UniSTS
Cd44  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map2E2UniSTS
cM Map256.0UniSTS
Cd44  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map2E2UniSTS
cM Map256.0UniSTS
Cd44  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map2E2UniSTS
cM Map256.0UniSTS
Cd44  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map2E2UniSTS
cM Map256.0UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001039150 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001039151 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001177785 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001177786 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001177787 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_009851 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006498646 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006498647 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006498648 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006498649 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AF069289 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF262063 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ251594 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK028981 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK045226 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK087472 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK144125 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK152099 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK154411 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK162720 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK166320 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK203354 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL844155 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC005676 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC025635 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC051388 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466519 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CT010324 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  J05163 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L13611 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M27129 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M27130 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M30655 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U57610 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U57611 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U57612 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X66081 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X66082 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X66083 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X66084 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X69724 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000005218   ⟹   ENSMUSP00000005218
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2102,641,486 - 102,731,970 (-)Ensembl
GRCm38.p6 Ensembl2102,811,141 - 102,901,625 (-)Ensembl
Ensembl Acc Id: ENSMUST00000060516   ⟹   ENSMUSP00000062330
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2102,642,875 - 102,731,840 (-)Ensembl
GRCm38.p6 Ensembl2102,812,530 - 102,901,495 (-)Ensembl
Ensembl Acc Id: ENSMUST00000099673   ⟹   ENSMUSP00000097265
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2102,642,892 - 102,731,855 (-)Ensembl
GRCm38.p6 Ensembl2102,812,547 - 102,901,510 (-)Ensembl
Ensembl Acc Id: ENSMUST00000111190   ⟹   ENSMUSP00000106821
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2102,644,465 - 102,731,695 (-)Ensembl
GRCm38.p6 Ensembl2102,814,120 - 102,901,350 (-)Ensembl
Ensembl Acc Id: ENSMUST00000111191   ⟹   ENSMUSP00000106822
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2102,644,465 - 102,731,714 (-)Ensembl
GRCm38.p6 Ensembl2102,814,120 - 102,901,369 (-)Ensembl
Ensembl Acc Id: ENSMUST00000111192   ⟹   ENSMUSP00000106823
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2102,644,478 - 102,731,691 (-)Ensembl
GRCm38.p6 Ensembl2102,814,133 - 102,901,346 (-)Ensembl
Ensembl Acc Id: ENSMUST00000111194   ⟹   ENSMUSP00000106825
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2102,641,486 - 102,732,010 (-)Ensembl
GRCm38.p6 Ensembl2102,811,141 - 102,901,665 (-)Ensembl
Ensembl Acc Id: ENSMUST00000111198   ⟹   ENSMUSP00000106829
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2102,644,475 - 102,731,695 (-)Ensembl
GRCm38.p6 Ensembl2102,814,130 - 102,901,350 (-)Ensembl
Ensembl Acc Id: ENSMUST00000124624
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2102,682,238 - 102,731,803 (-)Ensembl
GRCm38.p6 Ensembl2102,851,893 - 102,901,458 (-)Ensembl
RefSeq Acc Id: NM_001039150   ⟹   NP_001034239
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392102,641,486 - 102,732,010 (-)NCBI
GRCm382102,811,141 - 102,901,665 (-)NCBI
MGSCv372102,651,298 - 102,741,822 (-)RGD
Celera2104,054,974 - 104,145,651 (-)RGD
cM Map2 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001039151   ⟹   NP_001034240
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392102,641,486 - 102,732,010 (-)NCBI
GRCm382102,811,141 - 102,901,665 (-)NCBI
MGSCv372102,651,298 - 102,741,822 (-)RGD
Celera2104,054,974 - 104,145,651 (-)RGD
cM Map2 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001177785   ⟹   NP_001171256
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392102,641,486 - 102,732,010 (-)NCBI
GRCm382102,811,141 - 102,901,665 (-)NCBI
MGSCv372102,651,298 - 102,741,822 (-)RGD
Celera2104,054,974 - 104,145,651 (-)RGD
cM Map2 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001177786   ⟹   NP_001171257
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392102,641,486 - 102,732,010 (-)NCBI
GRCm382102,811,141 - 102,901,665 (-)NCBI
MGSCv372102,651,298 - 102,741,822 (-)RGD
Celera2104,054,974 - 104,145,651 (-)RGD
cM Map2 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001177787   ⟹   NP_001171258
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392102,641,486 - 102,732,010 (-)NCBI
GRCm382102,811,141 - 102,901,665 (-)NCBI
MGSCv372102,651,298 - 102,741,822 (-)RGD
Celera2104,054,974 - 104,145,651 (-)RGD
cM Map2 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_009851   ⟹   NP_033981
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392102,641,486 - 102,732,010 (-)NCBI
GRCm382102,811,141 - 102,901,665 (-)NCBI
MGSCv372102,651,298 - 102,741,822 (-)RGD
Celera2104,054,974 - 104,145,651 (-)RGD
cM Map2 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006498646   ⟹   XP_006498709
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392102,641,486 - 102,732,014 (-)NCBI
GRCm382102,811,141 - 102,901,669 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006498647   ⟹   XP_006498710
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392102,641,486 - 102,732,014 (-)NCBI
GRCm382102,811,141 - 102,901,669 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006498648   ⟹   XP_006498711
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392102,662,518 - 102,732,014 (-)NCBI
GRCm382102,832,173 - 102,901,669 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006498649   ⟹   XP_006498712
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392102,641,486 - 102,732,014 (-)NCBI
GRCm382102,811,141 - 102,901,669 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001034239 (Get FASTA)   NCBI Sequence Viewer  
  NP_001034240 (Get FASTA)   NCBI Sequence Viewer  
  NP_001171256 (Get FASTA)   NCBI Sequence Viewer  
  NP_001171257 (Get FASTA)   NCBI Sequence Viewer  
  NP_001171258 (Get FASTA)   NCBI Sequence Viewer  
  NP_033981 (Get FASTA)   NCBI Sequence Viewer  
  XP_006498709 (Get FASTA)   NCBI Sequence Viewer  
  XP_006498710 (Get FASTA)   NCBI Sequence Viewer  
  XP_006498711 (Get FASTA)   NCBI Sequence Viewer  
  XP_006498712 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA37145 (Get FASTA)   NCBI Sequence Viewer  
  AAA37406 (Get FASTA)   NCBI Sequence Viewer  
  AAA37407 (Get FASTA)   NCBI Sequence Viewer  
  AAA39922 (Get FASTA)   NCBI Sequence Viewer  
  AAA39923 (Get FASTA)   NCBI Sequence Viewer  
  AAB08756 (Get FASTA)   NCBI Sequence Viewer  
  AAC52804 (Get FASTA)   NCBI Sequence Viewer  
  AAC52805 (Get FASTA)   NCBI Sequence Viewer  
  AAC52806 (Get FASTA)   NCBI Sequence Viewer  
  AAH05676 (Get FASTA)   NCBI Sequence Viewer  
  AAH51388 (Get FASTA)   NCBI Sequence Viewer  
  BAC32269 (Get FASTA)   NCBI Sequence Viewer  
  BAE25715 (Get FASTA)   NCBI Sequence Viewer  
  BAE30946 (Get FASTA)   NCBI Sequence Viewer  
  BAE32566 (Get FASTA)   NCBI Sequence Viewer  
  BAE38703 (Get FASTA)   NCBI Sequence Viewer  
  CAA46880 (Get FASTA)   NCBI Sequence Viewer  
  CAA46881 (Get FASTA)   NCBI Sequence Viewer  
  CAA46882 (Get FASTA)   NCBI Sequence Viewer  
  CAA46883 (Get FASTA)   NCBI Sequence Viewer  
  CAA49380 (Get FASTA)   NCBI Sequence Viewer  
  CAB61888 (Get FASTA)   NCBI Sequence Viewer  
  CAJ18532 (Get FASTA)   NCBI Sequence Viewer  
  EDL27676 (Get FASTA)   NCBI Sequence Viewer  
  EDL27677 (Get FASTA)   NCBI Sequence Viewer  
  EDL27678 (Get FASTA)   NCBI Sequence Viewer  
  EDL27679 (Get FASTA)   NCBI Sequence Viewer  
  EDL27680 (Get FASTA)   NCBI Sequence Viewer  
  EDL27681 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000005218
  ENSMUSP00000062330
  ENSMUSP00000097265
  ENSMUSP00000106821
  ENSMUSP00000106822
  ENSMUSP00000106829
GenBank Protein P15379 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001034240   ⟸   NM_001039151
- Peptide Label: isoform c precursor
- UniProtKB: Q3U8S1 (UniProtKB/TrEMBL),   Q3U468 (UniProtKB/TrEMBL),   Q3UNN2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001034239   ⟸   NM_001039150
- Peptide Label: isoform b precursor
- UniProtKB: Q80X37 (UniProtKB/TrEMBL),   E9QKM8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_033981   ⟸   NM_009851
- Peptide Label: isoform a precursor
- UniProtKB: Q62061 (UniProtKB/Swiss-Prot),   Q62060 (UniProtKB/Swiss-Prot),   Q61395 (UniProtKB/Swiss-Prot),   Q05732 (UniProtKB/Swiss-Prot),   Q9QYX8 (UniProtKB/Swiss-Prot),   Q99J14 (UniProtKB/Swiss-Prot),   Q64296 (UniProtKB/Swiss-Prot),   Q62409 (UniProtKB/Swiss-Prot),   Q62408 (UniProtKB/Swiss-Prot),   Q62063 (UniProtKB/Swiss-Prot),   Q62062 (UniProtKB/Swiss-Prot),   P15379 (UniProtKB/Swiss-Prot),   A2APM2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001171256   ⟸   NM_001177785
- Peptide Label: isoform d precursor
- UniProtKB: A2APM1 (UniProtKB/TrEMBL),   E9QKM8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001171257   ⟸   NM_001177786
- Peptide Label: isoform e precursor
- UniProtKB: A2APM4 (UniProtKB/TrEMBL),   A2APM5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001171258   ⟸   NM_001177787
- Peptide Label: isoform f precursor
- UniProtKB: A2APM3 (UniProtKB/TrEMBL),   A2APM5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006498709   ⟸   XM_006498646
- Peptide Label: isoform X1
- UniProtKB: Q9QYX8 (UniProtKB/Swiss-Prot),   Q99J14 (UniProtKB/Swiss-Prot),   Q64296 (UniProtKB/Swiss-Prot),   Q62409 (UniProtKB/Swiss-Prot),   Q62408 (UniProtKB/Swiss-Prot),   Q62063 (UniProtKB/Swiss-Prot),   Q62062 (UniProtKB/Swiss-Prot),   Q62061 (UniProtKB/Swiss-Prot),   Q62060 (UniProtKB/Swiss-Prot),   Q61395 (UniProtKB/Swiss-Prot),   Q05732 (UniProtKB/Swiss-Prot),   P15379 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006498710   ⟸   XM_006498647
- Peptide Label: isoform X2
- UniProtKB: Q9QYX8 (UniProtKB/Swiss-Prot),   Q99J14 (UniProtKB/Swiss-Prot),   Q64296 (UniProtKB/Swiss-Prot),   Q62409 (UniProtKB/Swiss-Prot),   Q62408 (UniProtKB/Swiss-Prot),   Q62063 (UniProtKB/Swiss-Prot),   Q62062 (UniProtKB/Swiss-Prot),   Q62061 (UniProtKB/Swiss-Prot),   Q62060 (UniProtKB/Swiss-Prot),   Q61395 (UniProtKB/Swiss-Prot),   Q05732 (UniProtKB/Swiss-Prot),   P15379 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006498712   ⟸   XM_006498649
- Peptide Label: isoform X4
- UniProtKB: E9QKM8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006498711   ⟸   XM_006498648
- Peptide Label: isoform X3
- Sequence:
Ensembl Acc Id: ENSMUSP00000106829   ⟸   ENSMUST00000111198
Ensembl Acc Id: ENSMUSP00000106825   ⟸   ENSMUST00000111194
Ensembl Acc Id: ENSMUSP00000106821   ⟸   ENSMUST00000111190
Ensembl Acc Id: ENSMUSP00000106822   ⟸   ENSMUST00000111191
Ensembl Acc Id: ENSMUSP00000106823   ⟸   ENSMUST00000111192
Ensembl Acc Id: ENSMUSP00000097265   ⟸   ENSMUST00000099673
Ensembl Acc Id: ENSMUSP00000062330   ⟸   ENSMUST00000060516
Ensembl Acc Id: ENSMUSP00000005218   ⟸   ENSMUST00000005218
Protein Domains
Link

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P15379-F1-model_v2 AlphaFold P15379 1-778 view protein structure

Promoters
RGD ID:6830981
Promoter ID:MM_KWN:30761
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:MEF_B6
Transcripts:OTTMUST00000035232
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv362102,680,251 - 102,680,751 (-)MPROMDB
RGD ID:6830980
Promoter ID:MM_KWN:30763
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000005218,   ENSMUST00000060516,   ENSMUST00000099673,   ENSMUST00000111189,   ENSMUST00000111192,   ENSMUST00000111193,   ENSMUST00000111194,   ENSMUST00000111195,   ENSMUST00000111196,   ENSMUST00000111197,   ENSMUST00000111198,   ENSMUST00000111199,   ENSMUST00000111200,   OTTMUST00000035229,   UC008LII.1,   UC008LIJ.1,   UC008LIK.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv362102,741,496 - 102,742,052 (-)MPROMDB
RGD ID:6878060
Promoter ID:EPDNEW_M2481
Type:initiation region
Name:Cd44_1
Description:Mus musculus CD44 antigen , transcript variant 3, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm382102,901,458 - 102,901,518EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:88338 AgrOrtholog
Ensembl Genes ENSMUSG00000005087 Ensembl, ENTREZGENE
Ensembl Transcript ENSMUST00000005218 ENTREZGENE
  ENSMUST00000060516 ENTREZGENE
  ENSMUST00000099673 ENTREZGENE
  ENSMUST00000111190 ENTREZGENE
  ENSMUST00000111191 ENTREZGENE
  ENSMUST00000111198 ENTREZGENE
Gene3D-CATH 3.10.100.10 UniProtKB/Swiss-Prot
InterPro C-type_lectin-like/link_sf UniProtKB/Swiss-Prot
  CD44_antigen UniProtKB/Swiss-Prot
  CD44_antigen-like UniProtKB/Swiss-Prot
  CTDL_fold UniProtKB/Swiss-Prot
  Link_dom UniProtKB/Swiss-Prot
KEGG Report mmu:12505 UniProtKB/Swiss-Prot
MGD MGI:88338 ENTREZGENE
NCBI Gene 12505 ENTREZGENE
PANTHER PTHR10225 UniProtKB/Swiss-Prot
  PTHR10225:SF6 UniProtKB/Swiss-Prot
Pfam Xlink UniProtKB/Swiss-Prot
PhenoGen Cd44 PhenoGen
PRINTS CD44 UniProtKB/Swiss-Prot
  LINKMODULE UniProtKB/Swiss-Prot
PROSITE LINK_1 UniProtKB/Swiss-Prot
  LINK_2 UniProtKB/Swiss-Prot
SMART LINK UniProtKB/Swiss-Prot
Superfamily-SCOP SSF56436 UniProtKB/Swiss-Prot
UniProt A2APM1 ENTREZGENE, UniProtKB/TrEMBL
  A2APM2 ENTREZGENE, UniProtKB/TrEMBL
  A2APM3 ENTREZGENE, UniProtKB/TrEMBL
  A2APM4 ENTREZGENE, UniProtKB/TrEMBL
  A2APM5 ENTREZGENE, UniProtKB/TrEMBL
  CD44_MOUSE UniProtKB/Swiss-Prot
  E9QKM8 ENTREZGENE, UniProtKB/TrEMBL
  P15379 ENTREZGENE
  Q05732 ENTREZGENE
  Q3TLT9_MOUSE UniProtKB/TrEMBL
  Q3U468 ENTREZGENE, UniProtKB/TrEMBL
  Q3U8S1 ENTREZGENE, UniProtKB/TrEMBL
  Q3UNN2 ENTREZGENE, UniProtKB/TrEMBL
  Q61395 ENTREZGENE
  Q62060 ENTREZGENE
  Q62061 ENTREZGENE
  Q62062 ENTREZGENE
  Q62063 ENTREZGENE
  Q62408 ENTREZGENE
  Q62409 ENTREZGENE
  Q64296 ENTREZGENE
  Q80X37 ENTREZGENE, UniProtKB/TrEMBL
  Q99J14 ENTREZGENE
  Q9QYX8 ENTREZGENE
UniProt Secondary Q05732 UniProtKB/Swiss-Prot
  Q61395 UniProtKB/Swiss-Prot
  Q62060 UniProtKB/Swiss-Prot
  Q62061 UniProtKB/Swiss-Prot
  Q62062 UniProtKB/Swiss-Prot
  Q62063 UniProtKB/Swiss-Prot
  Q62408 UniProtKB/Swiss-Prot
  Q62409 UniProtKB/Swiss-Prot
  Q64296 UniProtKB/Swiss-Prot
  Q99J14 UniProtKB/Swiss-Prot
  Q9QYX8 UniProtKB/Swiss-Prot