Bcl2 (B cell leukemia/lymphoma 2) - Rat Genome Database

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Gene: Bcl2 (B cell leukemia/lymphoma 2) Mus musculus
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Symbol: Bcl2
Name: B cell leukemia/lymphoma 2
RGD ID: 10230
MGI Page MGI
Description: Enables molecular adaptor activity and protein phosphatase 2A binding activity. Involved in several processes, including hair follicle morphogenesis; mitochondrion organization; and negative regulation of reactive oxygen species metabolic process. Acts upstream of or within several processes, including apoptotic signaling pathway; hemopoiesis; and negative regulation of programmed cell death. Located in several cellular components, including mitochondrial membrane; myelin sheath; and nuclear membrane. Is expressed in several structures, including central nervous system; genitourinary system; gut; limb; and sensory organ. Used to study oligomeganephronia. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; carcinoma (multiple); hematologic cancer (multiple); intracranial aneurysm; and prostate cancer. Orthologous to human BCL2 (BCL2 apoptosis regulator).
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: apoptosis regulator Bcl-2; AW986256; B-cell leukemia/lymphoma 2; Bcl-; Bcl-2; C430015F12Rik; D630044D05Rik; D830018M01Rik
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
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Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391106,465,906 - 106,642,020 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1106,465,908 - 106,642,004 (-)EnsemblGRCm39 Ensembl
GRCm381106,538,176 - 106,714,290 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1106,538,178 - 106,714,274 (-)EnsemblGRCm38mm10GRCm38
MGSCv371108,434,756 - 108,610,867 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361108,365,740 - 108,541,849 (-)NCBIMGSCv36mm8
Celera1109,386,734 - 109,563,656 (-)NCBICelera
Cytogenetic Map1E2.1NCBI
cM Map149.76NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model