Avp (arginine vasopressin) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Avp (arginine vasopressin) Mus musculus
Analyze
Symbol: Avp
Name: arginine vasopressin
RGD ID: 10220
MGI Page MGI
Description: Predicted to enable several functions, including cysteine-type endopeptidase inhibitor activity involved in apoptotic process; neuropeptide hormone activity; and vasopressin receptor binding activity. Predicted to be involved in several processes, including intracellular signal transduction; negative regulation of cell communication; and positive regulation of macromolecule metabolic process. Predicted to act upstream of or within vasoconstriction. Predicted to be located in dendrite and extracellular region. Predicted to be active in extracellular space and neuronal dense core vesicle. Is expressed in several structures, including alimentary system; cardiovascular system; integumental system; nervous system; and sensory organ. Used to study neurohypophyseal diabetes insipidus. Human ortholog(s) of this gene implicated in diabetes insipidus and neurohypophyseal diabetes insipidus. Orthologous to human AVP (arginine vasopressin).
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: AVP-NPII; pre-pro-arginine-vasopressin-neurophysin II; prepro-AVP-NP II; vasopressin-neurophysin 2-copeptin; Vp; Vsp
RGD Orthologs
Human
Rat
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392130,422,540 - 130,424,508 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2130,422,540 - 130,424,474 (-)EnsemblGRCm39 Ensembl
GRCm382130,580,620 - 130,582,588 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2130,580,620 - 130,582,554 (-)EnsemblGRCm38mm10GRCm38
MGSCv372130,406,413 - 130,408,277 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362130,272,118 - 130,273,982 (-)NCBIMGSCv36mm8
Celera2131,805,101 - 131,806,965 (-)NCBICelera
Cytogenetic Map2F1NCBI
cM Map263.24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(R)-noradrenaline  (ISO)
(S)-colchicine  (ISO)
(S)-nicotine  (EXP,ISO)
1-(propan-2-ylamino)-3-(2-prop-2-enoxyphenoxy)-2-propanol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (ISO)
2,6-dinitrotoluene  (ISO)
3',5'-cyclic AMP  (ISO)
3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine  (ISO)
3,3',5-triiodo-L-thyronine  (ISO)
3-\{1-[3-(dimethylamino)propyl]-1H-indol-3-yl\}-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione  (ISO)
5'-phosphopyridoxal-6-azobenzene-2,4-disulfonic acid  (ISO)
6-oxoprostaglandin F1alpha  (ISO)
actinomycin D  (ISO)
all-trans-retinoic acid  (EXP)
Allylamine  (ISO)
AM-251  (ISO)
ammonium chloride  (ISO)
apomorphine  (ISO)
arachidonic acid  (ISO)
arachidonyl-2'-chloroethylamide  (ISO)
Aroclor 1254  (ISO)
ATP  (ISO)
atrazine  (EXP)
benzo[a]pyrene  (EXP,ISO)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisphenol A  (EXP,ISO)
BQ 123  (ISO)
butan-1-ol  (ISO)
Butylparaben  (ISO)
C60 fullerene  (ISO)
cadmium dichloride  (EXP,ISO)
calcium atom  (ISO)
calcium(0)  (ISO)
carvedilol  (ISO)
chloroquine  (ISO)
chlorpromazine  (ISO)
chlorpropamide  (ISO)
chlorpyrifos  (ISO)
chromium atom  (ISO)
clonidine  (ISO)
clonidine (amino form)  (ISO)
clonidine (imino form)  (ISO)
corticosterone  (ISO)
cyanamide  (ISO)
DDE  (ISO)
desflurane  (ISO)
desmopressin  (EXP)
dexamethasone  (ISO)
diethylstilbestrol  (ISO)
diprotium oxide  (ISO)
doxorubicin  (ISO)
EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor  (ISO)
enalapril  (ISO)
enzacamene  (ISO)
ethanol  (ISO)
fluoxetine  (ISO)
fluvoxamine  (ISO)
folic acid  (EXP)
furan  (ISO)
genistein  (EXP)
Hexamethonium  (ISO)
hydrochlorothiazide  (ISO)
hydroxyflutamide  (ISO)
ifosfamide  (ISO)
indometacin  (ISO)
isoflurane  (ISO)
ketoconazole  (ISO)
labetalol  (ISO)
linsidomine  (ISO)
linuron  (ISO)
lipopolysaccharide  (EXP)
lithium atom  (ISO)
lithium chloride  (ISO)
lithium hydride  (ISO)
Mesna  (ISO)
methamphetamine  (ISO)
methotrexate  (ISO)
metoclopramide  (ISO)
microcystin RR  (EXP)
mifepristone  (ISO)
Muraglitazar  (ISO)
naloxone  (ISO)
nicardipine  (ISO)
nicotine  (EXP,ISO)
nifedipine  (ISO)
nitric oxide  (ISO)
oryzalin  (EXP)
paracetamol  (ISO)
paraquat  (EXP)
phenylephrine  (ISO)
phosphatidic acid  (ISO)
prazosin  (ISO)
progesterone  (ISO)
propofol  (ISO)
prostaglandin E2  (ISO)
raloxifene  (ISO)
SCH 23390  (ISO)
scopolamine  (ISO)
sodium chloride  (ISO)
sotrastaurin  (ISO)
streptozocin  (EXP)
Tesaglitazar  (ISO)
testosterone  (ISO)
tris(picolinato)chromium  (ISO)
urea  (ISO)
valproic acid  (ISO)
vincristine  (ISO)
water  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Physiology and pathophysiology of the vasopressin-regulated renal water reabsorption. Boone M and Deen PM, Pflugers Arch. 2008 Sep;456(6):1005-24. Epub 2008 Apr 23.
2. Utility of AVP gene testing in familial neurohypophyseal diabetes insipidus. Chitturi S, etal., Clin Endocrinol (Oxf). 2008 May 20.
3. Time course of c-fos, vasopressin and oxytocin mRNA expression in the hypothalamus following long-term dehydration. da Silveira LT, etal., Cell Mol Neurobiol. 2007 Aug;27(5):575-84.
4. Long-term gene therapy in the CNS: reversal of hypothalamic diabetes insipidus in the Brattleboro rat by using an adenovirus expressing arginine vasopressin. Geddes BJ, etal., Nat Med. 1997 Dec;3(12):1402-4. doi: 10.1038/nm1297-1402.
5. Arginine vasopressin in the pathogenesis of febrile convulsion and temporal lobe epilepsy. Gulec G and Noyan B, Neuroreport. 2002 Nov 15;13(16):2045-8.
6. Restriction of Drinking Water Abrogates Splanchnic Vasodilation and Portal Hypertension in Portal Vein-Ligated Rats. Heinemann A, etal., Pharmacology. 2008 Nov 6;83(1):26-32.
7. Science review: Vasopressin and the cardiovascular system part 1--receptor physiology. Holmes CL, etal., Crit Care. 2003 Dec;7(6):427-34. Epub 2003 Jun 26.
8. Increased expression of renal aquaporin water channels in spontaneously hypertensive rats. Lee J, etal., Kidney Blood Press Res. 2006;29(1):18-23. Epub 2006 Mar 22.
9. Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences Li DQ, etal., Zhejiang Da Xue Xue Bao Yi Xue Ban. 2008 Sep;37(5):468-71.
10. Vasopressin induces vascular superoxide via endothelin-1 in mineralocorticoid hypertension. Li L, etal., Hypertension. 2003 Mar;41(3 Pt 2):663-8. Epub 2002 Dec 16.
11. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
12. MGDs mouse GO annotations MGD data from the GO Consortium
13. Arginine-vasopressin mediates central and peripheral glucose regulation in response to carotid body receptor stimulation with Na-cyanide. Montero S, etal., J Appl Physiol. 2006 Jun;100(6):1902-9. Epub 2006 Feb 23.
14. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
15. Heterologous expression of human vasopressin-neurophysin precursors in a pituitary cell line: defective transport of a mutant protein from patients with familial diabetes insipidus. Olias G, etal., DNA Cell Biol 1996 Nov;15(11):929-35.
16. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
17. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
18. Vasopressin V(2)-receptor-dependent regulation of AQP2 expression in Brattleboro rats. Promeneur D, etal., Am J Physiol Renal Physiol. 2000 Aug;279(2):F370-82.
19. Adrenal hypersensitivity precedes chronic hypercorticism in streptozotocin-induced diabetes mice. Revsin Y, etal., Endocrinology. 2008 Jul;149(7):3531-9. Epub 2008 Apr 17.
20. Mouse MP Annotation Import Pipeline RGD automated import pipeline
21. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
22. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
23. Nocturnal polyuria with abnormal circadian rhythm of plasma arginine vasopressin in post-stroke patients. Sakakibara R, etal., Intern Med. 2005 Apr;44(4):281-4.
24. Inherited hypothalamic diabetes insipidus in the Brattleboro strain of rats. Saul GB 2nd, etal., J Hered 1968 Mar-Apr;59(2):113-7.
25. Single base deletion in the vasopressin gene is the cause of diabetes insipidus in Brattleboro rats. Schmale H and Richter D, Nature. 1984 Apr 19-25;308(5961):705-9. doi: 10.1038/308705a0.
26. Familial hypothalamic diabetes insipidus in rats. VALTIN H, etal., Nature. 1962 Dec 15;196:1109-10.
27. Apoptosis of supraoptic AVP neurons is involved in the development of central diabetes insipidus after hypophysectomy in rats. Wang Y, etal., BMC Neurosci. 2008 Jun 25;9:54.
28. Alterations in central neuropeptide expression, release, and receptor binding in rats bred for high anxiety: critical role of vasopressin. Wigger A, etal., Neuropsychopharmacology 2004 Jan;29(1):1-14.
29. Close association of severe hyponatremia with exaggerated release of arginine vasopressin in elderly subjects with secondary adrenal insufficiency. Yatagai T, etal., Eur J Endocrinol. 2003 Feb;148(2):221-6.
30. Enhanced expressions of arginine vasopressin (Avp) in the hypothalamic paraventricular and supraoptic nuclei of type 2 diabetic rats. Yi SS, etal., Neurochem Res. 2008 May;33(5):833-41. Epub 2007 Oct 17.
Additional References at PubMed
PMID:2176709   PMID:7539003   PMID:7830793   PMID:8432536   PMID:8543156   PMID:8617512   PMID:8672127   PMID:8863731   PMID:8972488   PMID:9023306   PMID:9090387   PMID:9678638  
PMID:9784500   PMID:10086356   PMID:10227427   PMID:10349636   PMID:10557207   PMID:10559399   PMID:10640708   PMID:10795924   PMID:10795925   PMID:11042159   PMID:11071765   PMID:11076861  
PMID:11089561   PMID:11217851   PMID:11290325   PMID:11318878   PMID:11381139   PMID:11773602   PMID:12477932   PMID:12508235   PMID:12531518   PMID:12590600   PMID:12944509   PMID:14660745  
PMID:14681479   PMID:14962074   PMID:14988428   PMID:15172884   PMID:15182301   PMID:15489334   PMID:15632412   PMID:16141072   PMID:16141073   PMID:16602821   PMID:16650525   PMID:16870944  
PMID:17298949   PMID:17356169   PMID:17684103   PMID:17717072   PMID:17853069   PMID:17893678   PMID:17953485   PMID:18001282   PMID:18448596   PMID:18499746   PMID:18673414   PMID:18697938  
PMID:19120108   PMID:19222558   PMID:19297548   PMID:19357765   PMID:19387470   PMID:19474326   PMID:19898468   PMID:19900438   PMID:19955494   PMID:20092567   PMID:20175210   PMID:20436479  
PMID:20453031   PMID:20495559   PMID:20876615   PMID:21048978   PMID:21084383   PMID:21178974   PMID:21247964   PMID:21267068   PMID:21354131   PMID:21456024   PMID:21525287   PMID:21571010  
PMID:21596839   PMID:21677750   PMID:21804012   PMID:21820436   PMID:21832120   PMID:21873635   PMID:21880835   PMID:21938401   PMID:21971157   PMID:22025668   PMID:22079582   PMID:22262306  
PMID:22665796   PMID:22945632   PMID:22962254   PMID:22992673   PMID:23136001   PMID:23273571   PMID:23386640   PMID:23403283   PMID:23674600   PMID:23784879   PMID:24185041   PMID:24194600  
PMID:24345477   PMID:24360909   PMID:24487620   PMID:24517977   PMID:24599304   PMID:24634830   PMID:24675466   PMID:24681257   PMID:24952961   PMID:25071457   PMID:25203138   PMID:25218558  
PMID:25315894   PMID:25392497   PMID:25653351   PMID:25741730   PMID:25782631   PMID:25863961   PMID:25864637   PMID:25907274   PMID:25926463   PMID:26232227   PMID:26232615   PMID:26342201  
PMID:26348989   PMID:26611327   PMID:27626074   PMID:27626380   PMID:27680940   PMID:27989461   PMID:28150369   PMID:28336531   PMID:28619276   PMID:28669546   PMID:28706241   PMID:28715127  
PMID:28807898   PMID:28920920   PMID:28963257   PMID:29043563   PMID:29364700   PMID:29643503   PMID:29679559   PMID:29931690   PMID:30422333   PMID:30879785   PMID:30918408   PMID:31006556  
PMID:31371721   PMID:31705443   PMID:31781038   PMID:31961993   PMID:32640184   PMID:32641825   PMID:32916091   PMID:33202247   PMID:33249461   PMID:33504846   PMID:33824970   PMID:33846232  
PMID:33869166   PMID:33887203   PMID:33990685   PMID:34062279   PMID:34139240   PMID:34526037   PMID:34585668   PMID:34705510   PMID:35008655   PMID:35023384   PMID:35045339   PMID:35108515  
PMID:35245348   PMID:35863346   PMID:35951005   PMID:36669474   PMID:36774552   PMID:37172583   PMID:37274219   PMID:37314252   PMID:37450603   PMID:37643163   PMID:37844254   PMID:37855039  
PMID:38247327   PMID:38355793   PMID:38384840  


Genomics

Comparative Map Data
Avp
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392130,422,540 - 130,424,508 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2130,422,540 - 130,424,474 (-)EnsemblGRCm39 Ensembl
GRCm382130,580,620 - 130,582,588 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2130,580,620 - 130,582,554 (-)EnsemblGRCm38mm10GRCm38
MGSCv372130,406,413 - 130,408,277 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362130,272,118 - 130,273,982 (-)NCBIMGSCv36mm8
Celera2131,805,101 - 131,806,965 (-)NCBICelera
Cytogenetic Map2F1NCBI
cM Map263.24NCBI
AVP
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38203,082,556 - 3,084,724 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl203,082,556 - 3,084,724 (-)EnsemblGRCh38hg38GRCh38
GRCh37203,063,202 - 3,065,370 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36203,011,202 - 3,013,370 (-)NCBINCBI36Build 36hg18NCBI36
Build 34203,011,202 - 3,013,370NCBI
Celera203,125,188 - 3,127,356 (-)NCBICelera
Cytogenetic Map20p13NCBI
HuRef203,011,450 - 3,013,197 (-)NCBIHuRef
CHM1_1203,057,749 - 3,065,399 (-)NCBICHM1_1
T2T-CHM13v2.0203,113,454 - 3,115,623 (-)NCBIT2T-CHM13v2.0
Avp
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83138,246,544 - 138,248,522 (-)NCBIGRCr8
mRatBN7.23117,793,447 - 117,805,091 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3117,793,457 - 117,795,425 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3121,687,900 - 121,689,880 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03130,285,159 - 130,287,139 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03127,944,031 - 127,946,011 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03123,117,482 - 123,119,460 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3123,117,492 - 123,119,460 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03129,615,610 - 129,627,147 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43118,205,007 - 118,206,985 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13118,110,580 - 118,112,558 (-)NCBI
Celera3116,604,316 - 116,606,294 (-)NCBICelera
Cytogenetic Map3q36NCBI
AVP
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2214,050,125 - 4,055,214 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1204,046,950 - 4,052,045 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0203,169,094 - 3,172,900 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1202,934,408 - 2,937,077 (-)NCBIpanpan1.1PanPan1.1panPan2
AVP
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12418,183,057 - 18,184,827 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2418,183,057 - 18,184,883 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2418,011,435 - 18,013,192 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02418,601,989 - 18,603,744 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2418,601,989 - 18,603,744 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12418,195,309 - 18,197,064 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02418,307,955 - 18,309,707 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02418,635,781 - 18,637,537 (+)NCBIUU_Cfam_GSD_1.0
AVP
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1732,581,234 - 32,583,185 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11732,581,234 - 32,583,145 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21736,950,915 - 36,952,826 (+)NCBISscrofa10.2Sscrofa10.2susScr3
AVP
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1233,761,066 - 33,764,608 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl233,761,140 - 33,763,172 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607110,750,976 - 10,753,915 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Avp
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247414,208,329 - 4,210,071 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247414,208,305 - 4,210,097 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Avp
32 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:135
Count of miRNA genes:132
Interacting mature miRNAs:135
Transcripts:ENSMUST00000046001
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301905Lgth2_mbody length 2 (mouse)Not determined2111173704145173821Mouse
1302033Nsv1_mNeuroadapted Sindbis viral RNA level 1 (mouse)Not determined2111623386145623526Mouse
13824983Vclq1_mcurvilinear velocity QTL 1 (mouse)261830344136841920Mouse
13506763Tbvq1_mtrabecular bone volume QTL 1 (mouse)2126041920135441920Mouse
11039520Ltpr2h_mLeishmania tropica response 2h (mouse)2112212746146213005Mouse
11039521Ltpr2g_mLeishmania tropica response 2g (mouse)2115212857149212994Mouse
12910799Pwgrq2_mpre-weaning growth rate QTL 2 (mouse)2118589253160611165Mouse
1302174Dssc2_mdextran sodium sulfate induced colitis QTL2 (mouse)Not determined224224632148700377Mouse
12910795Pwbwq5_mpost-weaning body weight QTL 5 (mouse)2118589253160611165Mouse
27226761Feml18_mfemur length 18, 16 week (mouse)294230345154241920Mouse
12910812Pwgrq1_mpre-weaning growth rate QTL 1 (mouse)2118589253160611165Mouse
12910814Pwbwq1_mpre-weaning body weight QTL 1 (mouse)2118589253160611165Mouse
4141854T2dm2sa_mtype 2 diabetes mellitus 2 in SMXA RI mice (mouse)Not determined229307947148374934Mouse
12904935Edlmmq2_mextensor digitorum longus muscle mass QTL 2 (mouse)297210364131210364Mouse
1302071Fembrs1_mfemur breaking strength 1 (mouse)Not determined2100942930134943090Mouse
10045885Cplaq15_mcircadian period of locomotor activity 15 (mouse)Not determined2110916118154354667Mouse
1302203Gvhd3_mgraft-versus host disease 3 (mouse)Not determined2100942930134943090Mouse
1300793Pcfm2_mperiosteal circumference and femur length 2 (mouse)Not determined2111173704145173821Mouse
10412082Hylaq1_mHyperlocomotor activity related QTL 1 (mouse)Not determined284013198148667470Mouse
1301822Pgia2_mproteoglycan induced arthritis 2 (mouse)Not determined2123937311157937424Mouse
5491197Mobq5_mmultigenic obesity QTL 5 (mouse)Not determined265269746162518926Mouse
5491196Mobq6_mmultigenic obesity QTL 6 (mouse)Not determined285724269180896594Mouse
1301031Bdln3_mbody length 3 (mouse)Not determined2127664019161664118Mouse
1301029T2dm3_mtype 2 diabetes mellitus 3 (mouse)Not determined2114288075132714157Mouse
27226788Feml13_mfemur length 13, 10 week (mouse)2102630345159941920Mouse
1301295Prdt1_mprion disease incubation time 1 (mouse)Not determined2116077623150077741Mouse
1301294Hrtfm5_mheart failure modifier 5 (mouse)Not determined2122883015156883131Mouse
12904954Gmmq2_mgastrocnemius muscle mass QTL 2 (mouse)297210364131210364Mouse
11038696Ltpr2f_mLeishmania tropica response 2f (mouse)2115212857149212994Mouse
1301330Tbbmd2_mtotal body bone mineral density 2 (mouse)Not determined2100942930134943090Mouse
1301201Chab1_mcholesterol absorption 1 (mouse)Not determined2111551028145551163Mouse
11038699Ltpr2b_mLeishmania tropica response 2b (mouse)2112212746146213005Mouse
11038700Ltpr2a_mLeishmania tropica response 2a (mouse)2112212746146213005Mouse
11038702Ltpr2_mLeishmania tropica response 2 (mouse)2103095716167212356Mouse
11049568Lmr28c_mleishmaniasis resistance 28c (mouse)297123370131123532Mouse
11049569Lmr28d_mleishmaniasis resistance 28d (mouse)297123370131123532Mouse
1301087Bbaa15_mB.burgdorferi-associated arthritis 15 (mouse)Not determined2110489658144489807Mouse
1301825Pbrgcsf1_mperipheral blood stem cell response to granulocyte colony stimulating factor 1 (mouse)Not determined2106233580140233729Mouse
4141802Ignpq1_mIgA nephropathy QTL 1 (mouse)Not determined2100824060134824269Mouse
1558990Skmw9_mskeletal muscle weight 9 (mouse)Not determined2111173704145173821Mouse
1301066Otx2m2_morthodenticle homolog 2 (Drosophila) modifier 2 (mouse)Not determined2123231973148700377Mouse
1558989Gnf4_mgrowth and fatness 4 (mouse)Not determined2128173704132714157Mouse
4141155Plast2b_mplasma plant sterol 2b (mouse)Not determined284013198148522175Mouse
1301618Bglu1_mblood glucose level 1 (mouse)Not determined2117942930174324863Mouse
27226749Femd10_mfemur midshaft diameter 10, 16 week (mouse)2124441920168241920Mouse
1301755Hrq1_mheart rate quantitative locus 1 (mouse)Not determined2111173704145173821Mouse
1302143Bwq5_mbody weight (mouse)Not determined2127664019161664118Mouse
12880427V25Dq3_mvitamin D inactive form serum level QTL 3 (mouse)2129341920163341920Mouse
1301344Lith1_mlithogenic gene 1 (mouse)Not determined245347635145312647Mouse
1558881Ses7_msalmonella enteritidis susceptibility 7 (mouse)Not determined2116306330150306474Mouse
10043875Bw25_mbody weight QTL 25 (mouse)Not determined2107255676141255676Mouse
1300712El2_mepilepsy 2 (mouse)Not determined2122207146142532135Mouse

Markers in Region
Avp  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map2F1UniSTS
cM Map273.2UniSTS


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000046001   ⟹   ENSMUSP00000035551
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2130,422,540 - 130,424,474 (-)Ensembl
GRCm38.p6 Ensembl2130,580,620 - 130,582,554 (-)Ensembl
RefSeq Acc Id: NM_009732   ⟹   NP_033862
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392130,422,540 - 130,424,508 (-)NCBI
GRCm382130,580,620 - 130,582,588 (-)NCBI
MGSCv372130,406,413 - 130,408,277 (-)RGD
Celera2131,805,101 - 131,806,965 (-)RGD
cM Map2 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_033862 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAC42027 (Get FASTA)   NCBI Sequence Viewer  
  AAH51997 (Get FASTA)   NCBI Sequence Viewer  
  BAE23570 (Get FASTA)   NCBI Sequence Viewer  
  EDL28280 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000035551
  ENSMUSP00000035551.7
GenBank Protein P35455 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_033862   ⟸   NM_009732
- Peptide Label: preproprotein
- UniProtKB: P35455 (UniProtKB/Swiss-Prot),   Q3UUQ5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000035551   ⟸   ENSMUST00000046001

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P35455-F1-model_v2 AlphaFold P35455 1-168 view protein structure

Promoters
RGD ID:6878762
Promoter ID:EPDNEW_M2832
Type:single initiation site
Name:Avp_1
Description:Mus musculus arginine vasopressin , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm382130,582,573 - 130,582,633EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:88121 AgrOrtholog
Ensembl Genes ENSMUSG00000037727 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000046001 ENTREZGENE
  ENSMUST00000046001.7 UniProtKB/Swiss-Prot
Gene3D-CATH 2.60.9.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Neurhyp_horm UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Neurhyp_horm_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Neurohypophysial_hormone_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:11998 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:88121 ENTREZGENE
NCBI Gene 11998 ENTREZGENE
PANTHER PTHR11681 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  VASOPRESSIN-NEUROPHYSIN 2-COPEPTIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Hormone_4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Hormone_5 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Avp PhenoGen
PIRSF Nonapeptide_hormone_precursor UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS NEUROPHYSIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE NEUROHYPOPHYS_HORM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROKAR_LIPOPROTEIN UniProtKB/TrEMBL
SMART SM00003 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF49606 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt NEU2_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q3UUQ5 ENTREZGENE, UniProtKB/TrEMBL