Aqp5 (aquaporin 5) - Rat Genome Database

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Gene: Aqp5 (aquaporin 5) Mus musculus
Analyze
Symbol: Aqp5
Name: aquaporin 5
RGD ID: 10184
MGI Page MGI
Description: Predicted to enable identical protein binding activity and water channel activity. Acts upstream of or within camera-type eye morphogenesis; saliva secretion; and water transport. Located in several cellular components, including apical plasma membrane; basal plasma membrane; and microvillus. Is expressed in several structures, including exocrine system; lung; nucleus pulposus; oocyte; and sensory organ. Used to study dry eye syndrome. Human ortholog(s) of this gene implicated in Bothnian type palmoplantar keratoderma. Orthologous to human AQP5 (aquaporin 5).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AQP-5; aquaporin-5
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391599,488,909 - 99,492,710 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1599,488,663 - 99,492,710 (+)EnsemblGRCm39 Ensembl
GRCm381599,591,028 - 99,594,829 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1599,590,782 - 99,594,829 (+)EnsemblGRCm38mm10GRCm38
MGSCv371599,421,459 - 99,425,260 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361599,418,814 - 99,422,856 (+)NCBIMGSCv36mm8
Celera15101,746,743 - 101,750,221 (+)NCBICelera
Cytogenetic Map15F1NCBI
cM Map1556.13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-pilocarpine  (EXP)
(S)-naringenin  (ISO)
1-naphthyl isothiocyanate  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-trinitrotoluene  (ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (EXP)
2-acetamidofluorene  (ISO)
2-hydroxypropanoic acid  (ISO)
3',5'-cyclic AMP  (EXP)
3-methylcholanthrene  (EXP,ISO)
4,4'-sulfonyldiphenol  (EXP)
4-hydroxyphenyl retinamide  (EXP)
5-azacytidine  (EXP)
7,12-dimethyltetraphene  (ISO)
acetamide  (ISO)
aflatoxin B1  (ISO)
aldehydo-D-glucose  (EXP)
all-trans-retinoic acid  (EXP)
amitrole  (ISO)
ammonium chloride  (ISO)
amoxicillin  (ISO)
amphotericin B  (ISO)
atropine  (EXP)
benzo[a]pyrene  (EXP,ISO)
bisphenol A  (EXP,ISO)
butanal  (ISO)
calcitriol  (ISO)
carbachol  (ISO)
chloroquine  (EXP)
choline  (EXP)
chromium(6+)  (EXP)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
cordycepin  (ISO)
D-glucose  (EXP)
decabromodiphenyl ether  (ISO)
dexamethasone  (EXP)
dibutyl phthalate  (EXP)
dioxygen  (ISO)
folic acid  (EXP)
fosfomycin  (ISO)
fructose  (EXP)
furan  (ISO)
genistein  (EXP)
glucose  (EXP)
glycyrrhizinic acid  (ISO)
herbicide  (EXP)
histamine  (ISO)
hydrogen peroxide  (ISO)
L-methionine  (EXP)
methimazole  (ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (ISO)
naringin  (EXP)
nickel atom  (ISO)
nitrofen  (ISO)
paraquat  (ISO)
potassium dichromate  (EXP)
progesterone  (EXP,ISO)
protein kinase inhibitor  (ISO)
quercetin  (ISO)
rac-lactic acid  (ISO)
roflumilast  (EXP,ISO)
silver atom  (EXP)
silver(0)  (EXP)
sulfadimethoxine  (ISO)
tamoxifen  (EXP)
terbutaline  (EXP)
tetrachloromethane  (ISO)
thalidomide  (EXP)
thiourea  (ISO)
titanium dioxide  (EXP)
tropan-3alpha-yl 3-hydroxy-2-phenylpropanoate  (EXP)
valproic acid  (ISO)
vinclozolin  (ISO)
zearalenone  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
2. Aquaporins in the kidney. Kwon TH, etal., Handb Exp Pharmacol. 2009;(190):95-132. doi: 10.1007/978-3-540-79885-9_5.
3. Impaired hearing in mice lacking aquaporin-4 water channels. Li J and Verkman AS, J Biol Chem 2001 Aug 17;276(33):31233-7. Epub 2001 Jun 13.
4. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
5. MGDs mouse GO annotations MGD data from the GO Consortium
6. MGD IEA MGD IEA
7. Functional requirement of aquaporin-5 in plasma membranes of sweat glands. Nejsum LN, etal., Proc Natl Acad Sci U S A 2002 Jan 8;99(1):511-516.
8. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
9. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
10. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
11. Mouse MP Annotation Import Pipeline RGD automated import pipeline
12. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
13. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
14. Temporal changes in expression of aquaporin-3, -4, -5 and -8 in rat brains after permanent focal cerebral ischemia. Yang M, etal., Brain Res. 2009 Sep 22;1290:121-32. Epub 2009 Jul 16.
15. miR-96 and miR-330 overexpressed and targeted AQP5 in lipopolysaccharide-induced rat lung damage of disseminated intravascular coagulation. Zhang Y, etal., Blood Coagul Fibrinolysis. 2014 Oct;25(7):731-7. doi: 10.1097/MBC.0000000000000133.
Additional References at PubMed
PMID:6185614   PMID:8621489   PMID:9325187   PMID:9757370   PMID:9822113   PMID:10337625   PMID:10349636   PMID:10400615   PMID:10619865   PMID:10719795   PMID:10788316   PMID:10795927  
PMID:10856128   PMID:10870513   PMID:11042159   PMID:11066060   PMID:11076861   PMID:11290736   PMID:11382807   PMID:11443343   PMID:11514581   PMID:11707570   PMID:11891232   PMID:11959831  
PMID:11989981   PMID:12031518   PMID:12042359   PMID:12096051   PMID:12361974   PMID:12477932   PMID:12565800   PMID:12783871   PMID:12941618   PMID:12943377   PMID:15003543   PMID:15005800  
PMID:15186480   PMID:15336546   PMID:15536076   PMID:15557451   PMID:15596131   PMID:15647389   PMID:15677768   PMID:15716345   PMID:16107722   PMID:16141072   PMID:16141073   PMID:16472605  
PMID:16571723   PMID:16602821   PMID:16691571   PMID:17035289   PMID:17097063   PMID:17164424   PMID:17360692   PMID:17377981   PMID:17428829   PMID:17438133   PMID:17521680   PMID:17665453  
PMID:17670744   PMID:18027168   PMID:18155156   PMID:18161062   PMID:18258849   PMID:18305162   PMID:18321928   PMID:18358466   PMID:18374910   PMID:18572159   PMID:18647319   PMID:18696337  
PMID:18816447   PMID:19136711   PMID:19215235   PMID:19237298   PMID:19299468   PMID:19367412   PMID:19465597   PMID:19521566   PMID:19574443   PMID:19767448   PMID:19892877   PMID:19897741  
PMID:20048339   PMID:20060823   PMID:20121927   PMID:20223754   PMID:20522648   PMID:20530543   PMID:20550619   PMID:20727874   PMID:21049041   PMID:21129374   PMID:21193966   PMID:21203896  
PMID:21267068   PMID:21270055   PMID:21350014   PMID:21385574   PMID:21408140   PMID:21455588   PMID:21482757   PMID:21513708   PMID:21633078   PMID:21704616   PMID:21721139   PMID:21745799  
PMID:21818558   PMID:21846814   PMID:21873635   PMID:22001906   PMID:22096492   PMID:22096573   PMID:22194995   PMID:22226856   PMID:22420587   PMID:22511580   PMID:22550388   PMID:22730381  
PMID:22916088   PMID:23063659   PMID:23195221   PMID:23313152   PMID:23326416   PMID:23341776   PMID:23405202   PMID:23408915   PMID:23451260   PMID:23466739   PMID:23469202   PMID:23473857  
PMID:23526992   PMID:23696835   PMID:23789091   PMID:23836893   PMID:23884556   PMID:23925155   PMID:23980576   PMID:24148248   PMID:24164893   PMID:24191021   PMID:24274330   PMID:24371813  
PMID:24391734   PMID:24429825   PMID:24499815   PMID:24662389   PMID:24733830   PMID:24747567   PMID:24879973   PMID:24903000   PMID:24939938   PMID:24941004   PMID:25079229   PMID:25091723  
PMID:25106429   PMID:25180700   PMID:25341032   PMID:25403566   PMID:25410786   PMID:25437438   PMID:25595964   PMID:25646474   PMID:25745107   PMID:25767807   PMID:25912685   PMID:25960294  
PMID:26067252   PMID:26235626   PMID:26252542   PMID:26272113   PMID:26329601   PMID:26416771   PMID:26586225   PMID:26711912   PMID:26816051   PMID:26847765   PMID:26984772   PMID:27035511  
PMID:27064541   PMID:27106761   PMID:27114614   PMID:27140635   PMID:27141870   PMID:27150575   PMID:27341756   PMID:27355685   PMID:27569535   PMID:27578791   PMID:27721237   PMID:27861515  
PMID:27871297   PMID:27910949   PMID:28088675   PMID:28484984   PMID:28576768   PMID:28615712   PMID:28623666   PMID:28811219   PMID:28827394   PMID:28838957   PMID:28839100   PMID:28877240  
PMID:29033846   PMID:29118028   PMID:29118970   PMID:29361536   PMID:29853539   PMID:29867931   PMID:29920187   PMID:29950483   PMID:29951954   PMID:30389913   PMID:30389914   PMID:30566624  
PMID:30782824   PMID:31067462   PMID:31221639   PMID:31241463   PMID:31548395   PMID:31882545   PMID:31953689   PMID:32001436   PMID:32025032   PMID:32046118   PMID:32059772   PMID:32063362  
PMID:32067289   PMID:32317081   PMID:32324833   PMID:32394892   PMID:32414917   PMID:32439762   PMID:32579851   PMID:32931478   PMID:33013441   PMID:33153107   PMID:33187367   PMID:33305192  
PMID:33542263   PMID:33582182   PMID:33707239   PMID:33830085   PMID:33840298   PMID:34247492   PMID:34323105   PMID:34390680   PMID:34455107   PMID:34497269   PMID:34540996   PMID:34585968  
PMID:34653670   PMID:34948308   PMID:35002213   PMID:35273595   PMID:35569195   PMID:35682694   PMID:36069228   PMID:36621535   PMID:36626177   PMID:36688817   PMID:36824022   PMID:36918428  
PMID:37497597   PMID:37586060   PMID:37707834   PMID:37838739   PMID:37841243   PMID:38146368   PMID:38311164   PMID:38354944   PMID:38722977   PMID:39017635  


Genomics

Comparative Map Data
Aqp5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391599,488,909 - 99,492,710 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1599,488,663 - 99,492,710 (+)EnsemblGRCm39 Ensembl
GRCm381599,591,028 - 99,594,829 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1599,590,782 - 99,594,829 (+)EnsemblGRCm38mm10GRCm38
MGSCv371599,421,459 - 99,425,260 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361599,418,814 - 99,422,856 (+)NCBIMGSCv36mm8
Celera15101,746,743 - 101,750,221 (+)NCBICelera
Cytogenetic Map15F1NCBI
cM Map1556.13NCBI
AQP5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381249,961,872 - 49,965,682 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1249,961,872 - 49,965,682 (+)EnsemblGRCh38hg38GRCh38
GRCh371250,355,655 - 50,359,465 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361248,641,546 - 48,645,227 (+)NCBINCBI36Build 36hg18NCBI36
Build 341248,641,545 - 48,645,227NCBI
Celera1249,151,383 - 49,155,562 (+)NCBICelera
Cytogenetic Map12q13.12NCBI
HuRef1247,386,849 - 47,390,948 (+)NCBIHuRef
CHM1_11250,321,440 - 50,325,624 (+)NCBICHM1_1
T2T-CHM13v2.01249,924,863 - 49,928,671 (+)NCBIT2T-CHM13v2.0
Aqp5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87132,601,528 - 132,605,060 (+)NCBIGRCr8
mRatBN7.27130,722,675 - 130,726,207 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7130,721,748 - 130,726,209 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7132,526,264 - 132,529,796 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07134,751,843 - 134,755,375 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07134,664,370 - 134,667,902 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07141,249,044 - 141,252,576 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7141,249,044 - 141,252,578 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X115,753,747 - 115,757,279 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47138,337,725 - 138,341,257 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17138,414,167 - 138,417,694 (+)NCBI
Celera7127,204,033 - 127,207,565 (+)NCBICelera
Cytogenetic Map7q36NCBI
Aqp5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955547558,927 - 564,376 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955547558,296 - 562,455 (+)NCBIChiLan1.0ChiLan1.0
AQP5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21044,223,016 - 44,226,823 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11244,219,778 - 44,223,584 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01238,789,505 - 38,793,305 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11239,683,503 - 39,687,772 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1239,684,008 - 39,687,127 (-)Ensemblpanpan1.1panPan2
AQP5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1274,735,313 - 4,742,975 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl274,735,538 - 4,737,650 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2741,517,676 - 41,521,418 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0274,785,875 - 4,789,618 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1274,750,857 - 4,754,598 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0274,740,684 - 4,744,421 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02741,912,308 - 41,916,050 (+)NCBIUU_Cfam_GSD_1.0
Aqp5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494565,521,588 - 65,525,295 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365127,639,668 - 7,642,756 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365127,639,518 - 7,643,242 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
AQP5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl515,876,407 - 15,880,067 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1515,876,527 - 15,879,608 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2516,079,774 - 16,082,855 (-)NCBISscrofa10.2Sscrofa10.2susScr3
AQP5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11146,190,504 - 46,195,461 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666037199,926,134 - 199,930,017 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Aqp5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248162,326,010 - 2,329,544 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248162,326,059 - 2,329,525 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Aqp5
121 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:458
Count of miRNA genes:236
Interacting mature miRNAs:270
Transcripts:ENSMUST00000088200, ENSMUST00000169082
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
26884442Sklq6_mskull length QTL 6, 5 week (mouse)156129481100797881Mouse
1300627Sluc26_msusceptibility to lung cancer 26 (mouse)Not determined1570345653104073951Mouse
1357526Hyplip2_mhyperlipidemia 2 (mouse)Not determined1512402203102896555Mouse
11528547Sluc34_msusceptibility to lung cancer 34 (mouse)1597884933102896555Mouse
1301918Skull22_mskull morphology 22 (mouse)Not determined1585901546104073951Mouse
14928306Manh79_mmandible shape 79 (mouse)1578847557104073951Mouse
1357894Epfpq3_mepididymal fat percentage QTL 3 (mouse)Not determined1578601103102901704Mouse
26884425Cvht2_mcranial vault height 2, 5 week (mouse)1528800146102008435Mouse
4142060W3q6_mweight 3 weeks QTL 6 (mouse)Not determined78601103102901704Mouse
12791003Aath8_maortic arch atherosclerosis 8 (mouse)1573430144104073951Mouse
11530038Sluc34b_msusceptibility to lung cancer 34b (mouse)1585896437104073951Mouse
11530037Sluc34a_msusceptibility to lung cancer 34a (mouse)1585896437104073951Mouse
1558985Eae32_mexperimental allergic encephalomyelitis susceptibility 32 (mouse)Not determined1532578416103425899Mouse
4141921Pstc3_mperiosteal circumference 3 (mouse)Not determined1567270698101270847Mouse
12880411V125Dq11_mvitamin D active form serum level QTL 11 (mouse)1578897881104073951Mouse
1301171Brm2_mbrachyury modifier 2 (mouse)Not determined156552537699525499Mouse
1300851Heal4_mwound healing/regeneration 4 (mouse)Not determined1577527592104073951Mouse
14747011Mancz13_mmandible centroid size 13 (mouse)1572382669104073951Mouse
10402490Dipa5_mdrug induced psychomotor activation 5 (mouse)Not determined1579163411104073951Mouse
1300726Pitm4_mprion incubation time 4 (mouse)Not determined1570349271104073951Mouse
1302197Bhr2_mbronchial hyperresponsiveness 2 (mouse)Not determined1564306334103425899Mouse
1302074Bmd4_mbone mineral density 4 (mouse)Not determined1556186708103425899Mouse
4141902Cia37_mcollagen induced arthritis 37 (mouse)Not determined1580884933104073951Mouse
14700689Carg5_mCandida albicans resistance gene 5 (mouse)1597697881103008427Mouse
4141581Dshv1_mdorsal hippocampal volume 1 (mouse)Not determined92788640103425899Mouse
26884399Humsd1_mhumerus midshaft diameter 1, 5 week (mouse)1548363396101708435Mouse
4141897Imrfq2_mimmune response to Factor IX QTL 2 (mouse)Not determined79908940104073951Mouse
1301284Cosz3_mcocaine seizure 3 (mouse)Not determined1580313634104073951Mouse
4141511Gdcr1_mglycerolphosphate dehydrogenase regulator 1 (mouse)Not determined82615474104073951Mouse
1357614Bmca_mbile mucin accumulation (mouse)Not determined1585896437104073951Mouse
1300648Dbsty4_mdiabesity 4 (mouse)Not determined1570349271104073951Mouse
1300974Pgia9_mproteoglycan induced arthritis 9 (mouse)Not determined1580884933104073951Mouse

Markers in Region
Aqp5  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381599,592,728 - 99,594,286UniSTSGRCm38
MGSCv371599,423,159 - 99,424,717UniSTSGRCm37
Celera15101,748,120 - 101,749,678UniSTS
Cytogenetic Map15F1UniSTS
cM Map1556.8UniSTS
cM Map1556.8UniSTS
Aqp5  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map15F1UniSTS
Aqp5  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map15F1UniSTS
cM Map1556.8UniSTS
Aqp5  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381599,593,246 - 99,594,310UniSTSGRCm38
MGSCv371599,423,677 - 99,424,741UniSTSGRCm37
Celera15101,748,638 - 101,749,702UniSTS
Cytogenetic Map15F1UniSTS
cM Map1556.8UniSTS


Sequence


Ensembl Acc Id: ENSMUST00000088200   ⟹   ENSMUSP00000085530
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1599,488,730 - 99,492,489 (+)Ensembl
GRCm38.p6 Ensembl1599,590,849 - 99,594,608 (+)Ensembl
Ensembl Acc Id: ENSMUST00000169082   ⟹   ENSMUSP00000127611
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1599,488,663 - 99,492,710 (+)Ensembl
GRCm38.p6 Ensembl1599,590,782 - 99,594,829 (+)Ensembl
Ensembl Acc Id: ENSMUST00000229264
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1599,490,329 - 99,492,079 (+)Ensembl
GRCm38.p6 Ensembl1599,592,448 - 99,594,198 (+)Ensembl
Ensembl Acc Id: ENSMUST00000229728   ⟹   ENSMUSP00000155623
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1599,489,032 - 99,492,702 (+)Ensembl
GRCm38.p6 Ensembl1599,591,151 - 99,594,821 (+)Ensembl
Ensembl Acc Id: ENSMUST00000230998
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1599,489,741 - 99,492,703 (+)Ensembl
GRCm38.p6 Ensembl1599,591,860 - 99,594,822 (+)Ensembl
Ensembl Acc Id: ENSMUST00000231163   ⟹   ENSMUSP00000155212
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1599,489,115 - 99,492,547 (+)Ensembl
GRCm38.p6 Ensembl1599,591,234 - 99,594,666 (+)Ensembl
RefSeq Acc Id: NM_009701   ⟹   NP_033831
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391599,488,909 - 99,492,710 (+)NCBI
GRCm381599,591,028 - 99,594,829 (+)ENTREZGENE
MGSCv371599,421,459 - 99,425,260 (+)RGD
Celera15101,746,743 - 101,750,221 (+)RGD
cM Map15 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_033831   ⟸   NM_009701
- UniProtKB: Q545H1 (UniProtKB/Swiss-Prot),   Q9WTY4 (UniProtKB/Swiss-Prot),   B2RWZ5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000085530   ⟸   ENSMUST00000088200
Ensembl Acc Id: ENSMUSP00000155212   ⟸   ENSMUST00000231163
Ensembl Acc Id: ENSMUSP00000127611   ⟸   ENSMUST00000169082
Ensembl Acc Id: ENSMUSP00000155623   ⟸   ENSMUST00000229728

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9WTY4-F1-model_v2 AlphaFold Q9WTY4 1-265 view protein structure

Promoters
RGD ID:6825778
Promoter ID:MM_KWN:19694
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Lung
Transcripts:ENSMUST00000088200,   NM_009701,   UC007XPU.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361599,420,881 - 99,421,982 (+)MPROMDB
RGD ID:6849040
Promoter ID:MM_XEF:2687
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Lung
Transcripts:NM_001114607
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361599,423,181 - 99,423,681 (+)MPROMDB
RGD ID:8684996
Promoter ID:EPDNEW_M20529
Type:initiation region
Name:Aqp5_2
Description:Mus musculus aquaporin 5 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M20530  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381599,591,004 - 99,591,064EPDNEW
RGD ID:8685000
Promoter ID:EPDNEW_M20530
Type:multiple initiation site
Name:Aqp5_1
Description:Mus musculus aquaporin 5 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M20529  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381599,591,144 - 99,591,204EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:106215 AgrOrtholog
Ensembl Genes ENSMUSG00000044217 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000169082 ENTREZGENE
  ENSMUST00000169082.3 UniProtKB/Swiss-Prot
  ENSMUST00000229728.2 UniProtKB/TrEMBL
  ENSMUST00000231163.2 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1080.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Aquaporin-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Aquaporin_5 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Aquaporin_transptr UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MIP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MIP_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:11830 UniProtKB/Swiss-Prot
MGD MGI:106215 ENTREZGENE
NCBI Gene 11830 ENTREZGENE
PANTHER PTHR19139 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR19139:SF38 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam MIP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Aqp5 PhenoGen
PRINTS AQUAPORIN5 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MINTRINSICP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE MIP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF81338 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A2R8VHL2_MOUSE UniProtKB/TrEMBL
  A0A2R8VI16_MOUSE UniProtKB/TrEMBL
  AQP5_MOUSE UniProtKB/Swiss-Prot
  B2RWZ5 ENTREZGENE, UniProtKB/TrEMBL
  Q545H1 ENTREZGENE
  Q8CF61_MOUSE UniProtKB/TrEMBL
  Q9WTY4 ENTREZGENE
UniProt Secondary Q545H1 UniProtKB/Swiss-Prot