Agt (angiotensinogen) - Rat Genome Database

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Gene: Agt (angiotensinogen) Mus musculus
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Symbol: Agt
Name: angiotensinogen
RGD ID: 10118
MGI Page MGI
Description: Enables type 1 angiotensin receptor binding activity and type 2 angiotensin receptor binding activity. Involved in aldosterone secretion; positive regulation of cytokine production; and positive regulation of epithelial to mesenchymal transition. Acts upstream of or within several processes, including positive regulation of intracellular signal transduction; positive regulation of macromolecule metabolic process; and regulation of systemic arterial blood pressure by renin-angiotensin. Located in extracellular space. Is expressed in several structures, including axial skeleton; central nervous system; foregut mesenchyme; genitourinary system; and liver. Human ortholog(s) of this gene implicated in several diseases, including Fabry disease; Henoch-Schoenlein purpura; artery disease (multiple); heart conduction disease (multiple); and hydronephrosis. Orthologous to human AGT (angiotensinogen).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AI265500; AngI; AngII; angiotensin I; angiotensin ll; angiotensinogen (serpin peptidase inhibitor, clade A, member 8); Ao; Aogen; Se; serpin A8; Serpina8
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398125,283,326 - 125,296,445 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl8125,283,273 - 125,296,445 (-)EnsemblGRCm39 Ensembl
GRCm388124,556,587 - 124,569,706 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8124,556,534 - 124,569,706 (-)EnsemblGRCm38mm10GRCm38
MGSCv378127,080,487 - 127,093,607 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv368127,442,677 - 127,455,773 (-)NCBIMGSCv36mm8
Celera8128,860,995 - 128,873,954 (-)NCBICelera
Cytogenetic Map8E2NCBI
cM Map872.81NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View