Acadvl (acyl-Coenzyme A dehydrogenase, very long chain) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Acadvl (acyl-Coenzyme A dehydrogenase, very long chain) Mus musculus
Analyze
Symbol: Acadvl
Name: acyl-Coenzyme A dehydrogenase, very long chain
RGD ID: 10058
MGI Page MGI
Description: Predicted to enable acyl-CoA dehydrogenase activity; heterocyclic compound binding activity; and identical protein binding activity. Involved in fatty acid beta-oxidation using acyl-CoA dehydrogenase; regulation of lipid metabolic process; and temperature homeostasis. Acts upstream of or within fatty acid catabolic process and response to cold. Located in mitochondrion. Is expressed in several structures, including central nervous system; genitourinary system; gut gland; heart; and liver. Used to study very long chain acyl-CoA dehydrogenase deficiency. Human ortholog(s) of this gene implicated in very long chain acyl-CoA dehydrogenase deficiency. Orthologous to human ACADVL (acyl-CoA dehydrogenase very long chain).
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: MVLCAD; very long-chain specific acyl-CoA dehydrogenase, mitochondrial; VL; vlcad
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391169,901,009 - 69,906,254 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1169,901,009 - 69,906,237 (-)EnsemblGRCm39 Ensembl
GRCm381170,010,183 - 70,015,428 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1170,010,183 - 70,015,411 (-)EnsemblGRCm38mm10GRCm38
MGSCv371169,823,694 - 69,828,909 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361169,826,387 - 69,831,602 (-)NCBIMGSCv36mm8
Celera1177,558,144 - 77,563,359 (-)NCBICelera
Cytogenetic Map11B3NCBI
cM Map1142.96NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2,4-trimethylbenzene  (ISO)
1,2-dimethylhydrazine  (EXP)
1,4-benzoquinone  (ISO)
17beta-estradiol  (EXP)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (EXP)
2,6-dimethoxyphenol  (ISO)
2-palmitoylglycerol  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (EXP)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-hydroxyphenyl retinamide  (EXP,ISO)
5-aza-2'-deoxycytidine  (ISO)
6-propyl-2-thiouracil  (ISO)
acetamide  (ISO)
actinomycin D  (ISO)
aflatoxin B1  (EXP)
all-trans-retinoic acid  (ISO)
ammonium chloride  (ISO)
antimycin A  (ISO)
aristolochic acid A  (ISO)
Aroclor 1254  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
aspartame  (EXP)
atrazine  (ISO)
azoxystrobin  (ISO)
benzo[a]pyrene  (EXP,ISO)
beta-lapachone  (ISO)
bezafibrate  (EXP,ISO)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisphenol A  (ISO)
bisphenol AF  (ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
Brodifacoum  (ISO)
butan-1-ol  (ISO)
cadmium atom  (EXP,ISO)
cadmium dichloride  (ISO)
cannabidiol  (ISO)
CHIR 99021  (EXP)
chlorpyrifos  (EXP)
ciglitazone  (ISO)
cisplatin  (ISO)
clofibrate  (ISO)
Clofop  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
cyclosporin A  (EXP,ISO)
dexamethasone  (EXP)
dibutyl phthalate  (ISO)
doxorubicin  (EXP,ISO)
endosulfan  (ISO)
epoxiconazole  (EXP)
ethanol  (ISO)
fenamidone  (EXP)
fenofibrate  (EXP,ISO)
flavonoids  (ISO)
flutamide  (ISO)
fructose  (ISO)
fulvestrant  (ISO)
furan  (ISO)
furfural  (ISO)
gemfibrozil  (ISO)
gold atom  (ISO)
gold(0)  (ISO)
GW 4064  (ISO)
GW 501516  (ISO)
GW 7647  (ISO)
haloperidol  (ISO)
indometacin  (ISO)
isoprenaline  (ISO)
isotretinoin  (ISO)
ivermectin  (ISO)
leflunomide  (ISO)
lithocholic acid  (EXP)
meldonium  (EXP)
methapyrilene  (ISO)
methotrexate  (ISO)
microcystin-LR  (EXP)
mitoxantrone  (EXP)
monosodium L-glutamate  (EXP)
Muraglitazar  (ISO)
nitrates  (EXP)
Nutlin-3  (ISO)
oleic acid  (ISO)
p-toluidine  (ISO)
paracetamol  (ISO)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
perfluorooctanoic acid  (EXP,ISO)
picoxystrobin  (ISO)
pirinixic acid  (EXP,ISO)
piroxicam  (ISO)
propiconazole  (EXP)
pyrimidifen  (ISO)
quercetin  (ISO)
rotenone  (ISO)
SB 431542  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sodium chloride  (ISO)
Soman  (ISO)
sulforaphane  (EXP)
Tanshinone I  (ISO)
Tesaglitazar  (ISO)
tetrachloromethane  (EXP)
tetracycline  (EXP)
thapsigargin  (ISO)
thioacetamide  (ISO)
tributylstannane  (EXP)
trichloroethene  (EXP)
triphenyl phosphate  (ISO)
troglitazone  (ISO)
tunicamycin  (ISO)
valproic acid  (ISO)
zinc atom  (ISO)
zinc sulfate  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Potential roles of PINK1 for increased PGC-1alpha-mediated mitochondrial fatty acid oxidation and their associations with Alzheimer disease and diabetes. Choi J, etal., Mitochondrion. 2014 Sep;18:41-8. doi: 10.1016/j.mito.2014.09.005. Epub 2014 Sep 23.
2. Asperuloside stimulates metabolic function in rats across several organs under high-fat diet conditions, acting like the major ingredient of Eucommia leaves with anti-obesity activity. Fujikawa T, etal., J Nutr Sci. 2012 Sep 5;1:e10. doi: 10.1017/jns.2012.12. eCollection 2012.
3. Acyl-CoA dehydrogenases. A mechanistic overview. Ghisla S and Thorpe C, Eur J Biochem. 2004 Feb;271(3):494-508.
4. The modulation of hepatic adenosine triphosphate and inflammation by eicosapentaenoic acid during severe fibrotic progression in the SHRSP5/Dmcr rat model. Jia X, etal., Life Sci. 2012 Jun 14;90(23-24):934-43. doi: 10.1016/j.lfs.2012.04.029. Epub 2012 Apr 30.
5. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
6. Selenium significantly inhibits adipocyte hypertrophy and abdominal fat accumulation in OLETF rats via induction of fatty acid beta-oxidation. Kim JE, etal., Biol Trace Elem Res. 2012 Dec;150(1-3):360-70. doi: 10.1007/s12011-012-9519-1. Epub 2012 Oct 18.
7. Inhibition of very long chain acyl-CoA dehydrogenase during cardiac ischemia. Mason KE, etal., Arch Biochem Biophys. 2005 May 15;437(2):138-43. Epub 2005 Mar 19.
8. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
9. MGDs mouse GO annotations MGD data from the GO Consortium
10. MGD IEA MGD IEA
11. Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria. Mootha VK, etal., Cell 2003 Nov 26;115(5):629-40.
12. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
13. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
14. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
15. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
16. RefSeq and LocusLink: NCBI gene-centered resources Pruitt KD and Maglott DR, Nucleic Acids Res. 2001 Jan 1;29(1):137-40.
17. Heat stress modulates hepatocyte membrane proteins during endotoxemia. Przkora R, etal., Burns. 2007 Aug;33(5):628-33. Epub 2007 Mar 19.
18. Mouse MP Annotation Import Pipeline RGD automated import pipeline
19. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
20. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
21. Bioenergetics in glutaryl-coenzyme A dehydrogenase deficiency: a role for glutaryl-coenzyme A. Sauer SW, etal., J Biol Chem. 2005 Jun 10;280(23):21830-6. Epub 2005 Apr 19.
Additional References at PubMed
PMID:8889548   PMID:9195999   PMID:9345900   PMID:9680378   PMID:9861014   PMID:10349636   PMID:10754102   PMID:11042159   PMID:11076861   PMID:11590124   PMID:12477932   PMID:12893739  
PMID:14681479   PMID:15025677   PMID:15489334   PMID:15616563   PMID:15639194   PMID:15774826   PMID:15782199   PMID:15862275   PMID:16141072   PMID:16141073   PMID:16199475   PMID:16916647  
PMID:17075770   PMID:18317232   PMID:18614015   PMID:18628400   PMID:18980943   PMID:19465148   PMID:19736549   PMID:20444420   PMID:20446112   PMID:20580297   PMID:20640438   PMID:20727852  
PMID:20883455   PMID:21151927   PMID:21267068   PMID:21685264   PMID:21697078   PMID:21873635   PMID:21963783   PMID:22093833   PMID:22395529   PMID:22496890   PMID:23024820   PMID:23313579  
PMID:24116206   PMID:24285112   PMID:24530811   PMID:24648546   PMID:25662615   PMID:25721401   PMID:25811481   PMID:25887160   PMID:26284828   PMID:27884962   PMID:28130547   PMID:28159809  
PMID:29199018   PMID:29222160   PMID:29237229   PMID:29385670   PMID:29499131   PMID:29669786   PMID:29988383   PMID:30031688   PMID:30043753   PMID:30457570   PMID:30550785   PMID:31234015  
PMID:31235473   PMID:31394165   PMID:31971349   PMID:32325033   PMID:33448436   PMID:35449600   PMID:35727412   PMID:35733999   PMID:36114006   PMID:36417873   PMID:37225978   PMID:37558007  
PMID:37839992   PMID:38355793  


Genomics

Comparative Map Data
Acadvl
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391169,901,009 - 69,906,254 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1169,901,009 - 69,906,237 (-)EnsemblGRCm39 Ensembl
GRCm381170,010,183 - 70,015,428 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1170,010,183 - 70,015,411 (-)EnsemblGRCm38mm10GRCm38
MGSCv371169,823,694 - 69,828,909 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361169,826,387 - 69,831,602 (-)NCBIMGSCv36mm8
Celera1177,558,144 - 77,563,359 (-)NCBICelera
Cytogenetic Map11B3NCBI
cM Map1142.96NCBI
ACADVL
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38177,217,125 - 7,225,266 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl177,217,125 - 7,225,266 (+)EnsemblGRCh38hg38GRCh38
GRCh37177,120,444 - 7,128,585 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36177,063,877 - 7,069,309 (+)NCBINCBI36Build 36hg18NCBI36
Build 34177,063,956 - 7,069,306NCBI
Celera177,147,787 - 7,153,219 (+)NCBICelera
Cytogenetic Map17p13.1NCBI
HuRef177,012,512 - 7,020,576 (+)NCBIHuRef
CHM1_1177,129,209 - 7,137,334 (+)NCBICHM1_1
T2T-CHM13v2.0177,118,036 - 7,126,177 (+)NCBIT2T-CHM13v2.0
Acadvl
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81055,231,558 - 55,236,786 (-)NCBIGRCr8
mRatBN7.21054,732,875 - 54,738,102 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1054,732,469 - 54,738,075 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1059,395,021 - 59,400,168 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01058,883,601 - 58,888,748 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01054,390,891 - 54,396,038 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01056,619,321 - 56,624,468 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1056,619,303 - 56,624,526 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01056,364,440 - 56,369,587 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41056,856,233 - 56,861,380 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11056,869,857 - 56,875,003 (-)NCBI
Celera1053,886,459 - 53,891,606 (-)NCBICelera
Cytogenetic Map10q24NCBI
Acadvl
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554679,684,250 - 9,689,356 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554679,684,070 - 9,689,454 (-)NCBIChiLan1.0ChiLan1.0
ACADVL
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21914,812,517 - 14,817,937 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11716,778,578 - 16,783,944 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0177,249,717 - 7,255,165 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1177,236,286 - 7,242,417 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl177,234,283 - 7,242,417 (+)Ensemblpanpan1.1panPan2
ACADVL
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1532,189,191 - 32,194,255 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl532,186,502 - 32,327,990 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha532,327,393 - 32,332,562 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0532,294,698 - 32,299,874 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl532,292,139 - 32,335,711 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1532,260,008 - 32,265,180 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0532,219,055 - 32,224,215 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0532,395,976 - 32,401,145 (+)NCBIUU_Cfam_GSD_1.0
Acadvl
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560247,040,681 - 47,046,036 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936595514,534 - 520,223 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936595514,883 - 520,223 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ACADVL
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1252,576,402 - 52,581,748 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11252,573,521 - 52,581,755 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.23139,851,936 - 139,857,148 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ACADVL
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1166,593,288 - 6,598,980 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl166,593,287 - 6,598,979 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605914,811,795 - 14,817,522 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Acadvl
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247869,838,227 - 9,843,332 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247869,838,102 - 9,843,506 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:1228
Count of miRNA genes:569
Interacting mature miRNAs:673
Transcripts:ENSMUST00000018718, ENSMUST00000102574, ENSMUST00000134516, ENSMUST00000137187, ENSMUST00000145478, ENSMUST00000146129, ENSMUST00000156733
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
27226783Tibl5_mtibia length 5, 5 week (mouse)1168190826101890826Mouse
1300628Lgth6_mbody length 6 (mouse)Not determined1166733420100733652Mouse
4141367Inf1_macute ozone induced inflammation (mouse)Not determined44630038113058009Mouse
4141875Etax9_methanol induced ataxia 9 (mouse)Not determined5528498572209927Mouse
1300765Bbaa4_mB.burgdorferi-associated arthritis 4 (mouse)Not determined114618516780185262Mouse
1301788Lbw8_mlupus NZB x NZW 8 (mouse)Not determined113650328770509492Mouse
1302021Nidd1n_mnon-insulin-dependent diabetes mellitus 1 in NSY (mouse)Not determined114516587379978324Mouse
4142121Tmc1m2_mTmc1 modifier 2 (mouse)Not determined1156864027114157957Mouse
1301896Tria1_mT-cell receptor induced activation 1 (mouse)Not determined113661356570613855Mouse
4141982Skts-fp2_mskin tumor susceptibility in FVB and PWK 2 (mouse)Not determined5871926685066529Mouse
4141853Skmw17_mskeletal muscle weight 17 (mouse)Not determined113708094171081064Mouse
1357878Mastr_mmodifier of astrocytoma (mouse)Not determined114570858189818733Mouse
1300784Prdt3_mprion disease incubation time 3 (mouse)Not determined1166733420100733652Mouse
11039501Ltpr6a_mLeishmania tropica response 6a (mouse)116483033698830473Mouse
13208559Wght10_mweight 10 (mouse)11395000088890826Mouse
13524840Ppiq9a_mprepulse inhibition QTL 9a (mouse)115249438586494385Mouse
11039502Ltpr6b_mLeishmania tropica response 6b (mouse)116483033698830473Mouse
36049792Ars5_mantibody response to SARS-CoV 5, day 7, IgM (mouse)116899082672490826Mouse
13208558Lgth12_mbody length 12 (mouse)11395000094890826Mouse
1300664Etohcta9_methanol conditioned taste aversion 9 (mouse)Not determined115775466091754758Mouse
10053682Eae45_mexperimental allergic encephalomyelitis susceptibility 45 (mouse)Not determined115849055574754758Mouse
1300924Ity2_mimmunity to S. typhimurium 2 (mouse)Not determined15850803087695238Mouse
13208569Bmiq10_mbody mass index QTL 10 (mouse)113589082784890826Mouse
11039515Ltpr6_mLeishmania tropica response 6 (mouse)116483033698830473Mouse
11532699Sluc36b_msusceptibility to lung cancer 36b (mouse)114225661776256730Mouse
11532698Sluc36a_msusceptibility to lung cancer 36a (mouse)114225661776256730Mouse
1300774Pgia7_mproteoglycan induced arthritis 7 (mouse)Not determined115339058887390737Mouse
4141830Pregq1_mpregnancy QTL 1 (mouse)Not determined115412675283733652Mouse
1301546Pcir2_mperiosteal circumference 2 (mouse)Not determined1166733420100733652Mouse
1300905Scc6_mcolon tumor susceptibility 6 (mouse)Not determined11688027789019734Mouse
35673314Ari2_mantibody response to influenza 2, day 10, IgG3 (mouse)116899082672490826Mouse
39128214Lwq20_mliver weight QTL 20 (mouse)1112268637118022724Mouse
1301328Mol4_mmodifier of LPS-response 4 (mouse)Not determined113628257783481356Mouse
10412246Dfs2_mdental fluorosis suseptibility 2 (mouse)Not determined112180736495881231Mouse
1357766Si5lq6_mserum IGFBP-5 level QTL 6 (mouse)Not determined1166733420100733652Mouse
4142316Ity2b_mimmunity to S. typhimurium 2b (mouse)Not determined116707819179813912Mouse
1301319Dautb4_mdopamine uptake transporter binding 4 (mouse)Not determined116215600596156153Mouse
36049778Ars6_mantibody response to SARS-CoV 6, day 15, IgM (mouse)116899082672490826Mouse
1301830Ssta4_msusceptibility to Salmonella typhimurium antigens 4 (mouse)Not determined115007819184078411Mouse
36049779Ars7_mantibody response to SARS-CoV 7, day 29, IgG1 (mouse)116899082672490826Mouse
36049790Ars3_mantibody response to SARS-CoV 3, day 7, IgG2b (mouse)116899082672490826Mouse
36049791Ars4_mantibody response to SARS-CoV 4, day 7, IgG3 (mouse)116899082672490826Mouse
1301833Tbbmd5_mtotal body bone mineral density 5 (mouse)Not determined1166733420100733652Mouse
36049788Ars1_mantibody response to SARS-CoV 1, day 7, IgG1 (mouse)116899082672490826Mouse
36049789Ars2_mantibody response to SARS-CoV 2, day 7, IgG2a+IgG2c (mouse)116899082672490826Mouse
36049786Ars10_mantibody response to SARS-CoV 10, 4 days post-rechallenge, IgG2a+IgG2c (mouse)116899082672490826Mouse
10766457Nwa3_mNew Zealand White autoimmunity 3 (mouse)113801611572016209Mouse
36049787Ars11_mantibody response to SARS-CoV 11, 4 days post-rechallenge, IgM (mouse)116899082672490826Mouse
36049784Ars8_mantibody response to SARS-CoV 8, day 29, IgG2a+IgG2c (mouse)116899082672490826Mouse
36049785Ars9_mantibody response to SARS-CoV 9, day 29, IgM (mouse)116899082672490826Mouse
4142300Ctrq3_mC. trachomatis resistance QTL 3 (mouse)Not determined114463003876854757Mouse
4141012Femwf6_mfemur work to failure 6 (mouse)Not determined66733420100733652Mouse
1301987Pid3_mprior incubation determinant 3 (mouse)Not determined116168682088699728Mouse
27226730Tibmd1_mtibia midshaft diameter 1, 5 week (mouse)1162590826109390826Mouse
1301988Bmd11_mbone mineral density 11 (mouse)Not determined114631940780319522Mouse
4141894Nidd6k_mNidd6 on KK-A (mouse)Not determined1912420496897826Mouse
1301999Lmr15_mleishmaniasis resistance 15 (mouse)Not determined116331940781830473Mouse
10044004Stzid3_mstreptozotocin induced diabetes susceptibility 3 (mouse)Not determined116331940794063918Mouse
26884453Sklq16_mskull length QTL 16, 16 week (mouse)11325000072690826Mouse

Markers in Region
Acadvl  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map11B2-B5UniSTS
cM Map1138.0UniSTS
Dvl2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381170,009,712 - 70,009,942UniSTSGRCm38
MGSCv371169,823,214 - 69,823,444UniSTSGRCm37
Celera1177,557,664 - 77,557,894UniSTS
Cytogenetic Map11B3UniSTS
Cytogenetic Map11B2-B5UniSTS
Dvl2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381170,009,888 - 70,010,016UniSTSGRCm38
MGSCv371169,823,390 - 69,823,518UniSTSGRCm37
Celera1177,557,840 - 77,557,968UniSTS
Cytogenetic Map11B3UniSTS
Cytogenetic Map11B2-B5UniSTS
cM Map1136.5UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_017366 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AF017176 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AI843782 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ012054 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK076037 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK146334 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK180918 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK189988 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK196376 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK208302 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK211026 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK215457 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL596185 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AU067294 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC026559 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466596 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CR933541 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U41497 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Y11770 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Z71189 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000018718   ⟹   ENSMUSP00000018718
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1169,901,070 - 69,906,213 (-)Ensembl
GRCm38.p6 Ensembl1170,010,244 - 70,015,387 (-)Ensembl
Ensembl Acc Id: ENSMUST00000102574   ⟹   ENSMUSP00000099634
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1169,901,009 - 69,906,234 (-)Ensembl
GRCm38.p6 Ensembl1170,010,183 - 70,015,408 (-)Ensembl
Ensembl Acc Id: ENSMUST00000134516
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1169,901,015 - 69,901,737 (-)Ensembl
GRCm38.p6 Ensembl1170,010,189 - 70,010,911 (-)Ensembl
Ensembl Acc Id: ENSMUST00000137187
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1169,904,869 - 69,906,237 (-)Ensembl
GRCm38.p6 Ensembl1170,014,043 - 70,015,411 (-)Ensembl
Ensembl Acc Id: ENSMUST00000145478
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1169,904,944 - 69,906,225 (-)Ensembl
GRCm38.p6 Ensembl1170,014,118 - 70,015,399 (-)Ensembl
Ensembl Acc Id: ENSMUST00000146129
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1169,902,048 - 69,903,400 (-)Ensembl
GRCm38.p6 Ensembl1170,011,222 - 70,012,574 (-)Ensembl
Ensembl Acc Id: ENSMUST00000156733
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1169,904,015 - 69,906,203 (-)Ensembl
GRCm38.p6 Ensembl1170,013,189 - 70,015,377 (-)Ensembl
RefSeq Acc Id: NM_017366   ⟹   NP_059062
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391169,901,009 - 69,906,254 (-)NCBI
GRCm381170,010,183 - 70,015,428 (-)NCBI
MGSCv371169,823,694 - 69,828,909 (-)RGD
Celera1177,558,135 - 77,563,380 (-)NCBI
cM Map11 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_059062   ⟸   NM_017366
- Peptide Label: precursor
- UniProtKB: O35289 (UniProtKB/Swiss-Prot),   O55133 (UniProtKB/Swiss-Prot),   P50544 (UniProtKB/Swiss-Prot),   B1AR28 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000099634   ⟸   ENSMUST00000102574
Ensembl Acc Id: ENSMUSP00000018718   ⟸   ENSMUST00000018718
Protein Domains
ACAD9/ACADV-like C-terminal   Acyl-CoA dehydrogenase/oxidase C-terminal   Acyl-CoA dehydrogenase/oxidase N-terminal   Acyl-CoA oxidase/dehydrogenase middle

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P50544-F1-model_v2 AlphaFold P50544 1-656 view protein structure

Promoters
RGD ID:6820251
Promoter ID:MM_KWN:8170
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain,   Kidney,   Liver,   Lung
Transcripts:OTTMUST00000013535
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361169,823,974 - 69,824,474 (-)MPROMDB
RGD ID:6820252
Promoter ID:MM_KWN:8172
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day3,   3T3L1_Day4,   BoneMarrow_0Hour,   Brain,   Kidney,   Liver,   Lung,   MEF_B6,   Spleen
Transcripts:OTTMUST00000013536
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361169,825,841 - 69,826,982 (-)MPROMDB
RGD ID:6820250
Promoter ID:MM_KWN:8173
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6
Transcripts:ENSMUST00000018718,   OTTMUST00000013531,   OTTMUST00000013533,   OTTMUST00000013534,   OTTMUST00000038808
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361169,828,481 - 69,829,492 (-)MPROMDB
RGD ID:8675284
Promoter ID:EPDNEW_M15671
Type:initiation region
Name:Acadvl_1
Description:Mus musculus acyl-Coenzyme A dehydrogenase, very long chain ,mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381170,015,395 - 70,015,455EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:895149 AgrOrtholog
Ensembl Genes ENSMUSG00000018574 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000018718.8 UniProtKB/TrEMBL
  ENSMUST00000102574 ENTREZGENE
  ENSMUST00000102574.10 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.540.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.40.110.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Butyryl-CoA Dehydrogenase, subunit A, domain 3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro ACAD9/ACADV-like_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Acyl-CoA_DH_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Acyl-CoA_Oxase/DH_cen-dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Acyl-CoA_Oxase/DH_mid-dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  AcylCo_DH-like_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  AcylCo_DH/oxidase_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  AcylCoA_DH/ox_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  AcylCoA_DH/ox_N_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  AcylCoA_DH/oxidase_NM_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:11370 UniProtKB/Swiss-Prot
MGD MGI:895149 ENTREZGENE
NCBI Gene 11370 ENTREZGENE
PANTHER ACYL-COA DEHYDROGENASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  VERY LONG-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam ACAD9-ACADV_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Acyl-CoA_dh_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Acyl-CoA_dh_M UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Acyl-CoA_dh_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB ACADVL RGD
PhenoGen Acadvl PhenoGen
PROSITE ACYL_COA_DH_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ACYL_COA_DH_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF47203 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF56645 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt ACADV_MOUSE UniProtKB/Swiss-Prot
  B1AR28 ENTREZGENE, UniProtKB/TrEMBL
  O35289 ENTREZGENE
  O55133 ENTREZGENE
  P50544 ENTREZGENE
  Q3UJR6_MOUSE UniProtKB/TrEMBL
UniProt Secondary O35289 UniProtKB/Swiss-Prot
  O55133 UniProtKB/Swiss-Prot