Dmd<sup>em1Kykn</sup> (dystrophin; CRISPR/Cas9 system induced mutant 1, Keitaro Yamanouchi) - Rat Genome Database

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Gene: Dmdem1Kykn (dystrophin; CRISPR/Cas9 system induced mutant 1, Keitaro Yamanouchi) Rattus norvegicus
Analyze
Symbol: Dmdem1Kykn
Name: dystrophin; CRISPR/Cas9 system induced mutant 1, Keitaro Yamanouchi
RGD ID: 10045592
Description: mutation induced by CRISPR/Cas9 system in the Dmd gene resulting 329-bp deletion around exon 3 and 2-bp substitution in exon16.
ASSOCIATED WITH centrally nucleated skeletal muscle fibers; decreased body weight; decreased skeletal muscle fiber diameter; ASSOCIATED WITH Duchenne muscular dystrophy
Type: allele  of Dmd  
Previously known as: Dmdem1Kykn; Dmdem1Kykn
Is Marker For: Strains:   W-Dmdem1Kykn  
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Cytogenetic MapX RGD


Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Generation of muscular dystrophy model rats with a CRISPR/Cas system. Nakamura K, etal., Sci Rep. 2014 Jul 9;4:5635. doi: 10.1038/srep05635.
2. Strains registered by the National Bio Resource Project for the Rat in Japan Personal Communication with NBRP

Genomics


Related Rat Strains
The following Strains have been annotated to Dmdem1Kykn


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001005244 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles


Additional Information


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-06-12 Dmdem1Kykn  dystrophin; CRISPR/Cas9 system induced mutant 1, Keitaro Yamanouchi  Dmdem1Kykn  dystrophin; CRISPR/Cas9 system induced mutant 1, Keitaro Yamanouchi  Symbol changed 629549 APPROVED