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Cell Line : CVCL_0012 (LP-1) Homo sapiens

Symbol: CVCL_0012
Name: LP-1
Cell Line Type: cancer cell line
Origin: Derived from sampling site: Peripheral blood.
Gender: Female
Research Use: Omics: Array-based CGH; Omics: Deep antibody staining analysis; Omics: Deep exome analysis; Omics: Deep RNAseq analysis; Omics: DNA methylation analysis; Omics: Protein expression by reverse-phase protein arrays; Omics: SNP array analysis; Omics: Transcriptome analysis
Characteristics: Characteristics: Produces IgG lambda
Phenotype: Doubling time: 50 hours (PubMed=2784066); 48 hours (PubMed=25984343); 35-80 hours, depending on cell density (DSMZ); Microsatellite instability: Stable (MSS) (Sanger)
Genomic Alteration: Sequence variation: IGH-WHSC1 gene fusion (PubMed=31160637); Sequence variation: FGFR3 p.Phe384Leu (c.1150T>C) (PubMed=11157491); Sequence variation: Homozygous for TRAF3 p.Lys286Ilefs*7 (c.857_870delAGAGCATACAAAGT) (PubMed=17692805); Sequence variation: Homozygous for TP53 p.Glu286Lys (c.856G>A) (ClinVar=VCV000183752) (PubMed=21173094; Cosmic-CLP)
Groups: Part of: Cancer Cell Line Encyclopedia (CCLE) project; Part of: COSMIC cell lines project; Part of: LL-100 blood cancer cell line panel; Part of: MD Anderson Cell Lines Project
Description: HLA typing: A*03,24; B*07,18; C*07 (PubMed=25688540); Genome ancestry: African=0.21%; Native American=0%; East Asian, North=3.2%; East Asian, South=0%; South Asian=2.32%; European, North=42.82%; European, South=51.44% (PubMed=30894373)
Aliases: LP1
Disease(s): multiple myeloma (DOID:9538) [NCI:C3242,ORDO:29073]


References - uncurated

Additional Information

External Database Links
RGD Object Information
RGD ID: 21113476
Created: 2020-02-27
Species: Homo sapiens
Last Modified: 2020-02-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.