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Cell Line : CVCL_0001 (HEL) Homo sapiens

Symbol: CVCL_0001
Name: HEL
Cell Line Type: cancer cell line
Origin: Derived from sampling site: Peripheral blood.
Gender: Male
Research Use: Omics: Deep antibody staining analysis; Omics: Deep exome analysis; Omics: Deep quantitative proteome analysis; Omics: Deep RNAseq analysis; Omics: DNA methylation analysis; Omics: SNP array analysis; Omics: Transcriptome analysis
Phenotype: Doubling time: ~24 hours (PubMed=6177045); ~36 hours (DSMZ); Microsatellite instability: Stable (MSS) (Sanger)
Genomic Alteration: Sequence variation: Homozygous for JAK2 p.Val617Phe (c.1849G>T) (ClinVar=VCV000014662) (PubMed=16408098); Sequence variation: Homozygous for TP53 p.Met133Lys (c.398T>A) (CCLE; Cosmic-CLP)
Groups: Part of: Cancer Cell Line Encyclopedia (CCLE) project; Part of: COSMIC cell lines project; Part of: LL-100 blood cancer cell line panel
Description: Genome ancestry: African=2.4%; Native American=1.79%; East Asian, North=3.9%; East Asian, South=0%; South Asian=5.12%; European, North=13.33%; European, South=73.45% (PubMed=30894373)
Notes: Miscellaneous: Originally the patient was suffering from Hodgkin lymphoma
Child Cell Lines: CVCL_2481 (HEL 92.1.7)
CVCL_4360 (Dami)
CVCL_KS72 (CellSensor irf1-bla HEL)
CVCL_RS48 (HELrARA-C2mug/ML)
Aliases: GM06141; GM06141B; Hel; Human ErythroLeukemia


References

References - uncurated

Additional Information

External Database Links
 
RGD Object Information
RGD ID: 21113445
Created: 2020-02-27
Species: Homo sapiens
Last Modified: 2020-02-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.