GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | EIF2AK3 | increases phosphorylation | ISO | Eif2ak3 (Mus musculus) | 156430337 | RGD | streptozocin increases phosphorylation of Eif2ak3 protein in heart | | EIF2AK3 | increases phosphorylation | ISO | Eif2ak3 (Rattus norvegicus) | 6480464 | CTD | Streptozocin results in increased phosphorylation of EIF2AK3 protein | PMID:38049026 | EIF2AK3 | multiple interactions | ISO | Eif2ak3 (Rattus norvegicus) | 6480464 | CTD | [Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of EIF2AK3 protein; Chlorogenic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of EIF2AK3 protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of EIF2AK3 protein]; Vitamin B 12 inhibits the reaction [Streptozocin results in increased phosphorylation of EIF2AK3 protein] | PMID:34801538 PMID:38049026 | EIF2AK3 | multiple interactions | ISO | Eif2ak3 (Mus musculus) | 6480464 | CTD | [Dietary Fats co-treated with Streptozocin] results in increased expression of EIF2AK3 protein; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of EIF2AK3 protein] | PMID:33812996 | |
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