GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Pfkl | decreases activity | ISO | PFKL (Homo sapiens) | 6480464 | CTD | Penfluridol results in decreased activity of PFKL protein | PMID:35530161 | Pfkl | increases response to substance | ISO | PFKL (Homo sapiens) | 6480464 | CTD | PFKL protein results in increased susceptibility to Penfluridol | PMID:35530161 | Pfkl | multiple interactions | ISO | PFKL (Homo sapiens) | 6480464 | CTD | Penfluridol binds to and results in decreased activity of PFKL protein; PFKL protein affects the reaction [Penfluridol affects the localization of FOXO3A protein]; PFKL protein affects the reaction [Penfluridol results in increased cleavage of CASP3 protein]; PFKL protein affects the reaction [Penfluridol results in increased expression of BCL2L11 mRNA]; PFKL protein affects the reaction [Penfluridol results in increased expression of BCL2L11 protein] | PMID:35530161 | |
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