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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 11183
Species: Mus musculus
RGD Object: Gene
Symbol: Ptgis
Name: prostaglandin I2 (prostacyclin) synthase
Acc ID: CHEBI:90702
Term: carboxy-PTIO
Definition: A member of the class of imidazolines and organic radical that is 4,4,5,5-tetramethyl-3-oxo-4,5-dihydro-1H-3λ5-imidazol-1-yl]oxidanyl substituted at position 2 by a 4-carboxyphenyl group.
Chemical ID: MESH:C079393
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ptgisdecreases activityISOPtgis (Rattus norvegicus)401960074RGDcPTIO decreases activity of Ptgis protein in the aorta 
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