GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Mapk8 | increases activity | ISO | MAPK8 (Homo sapiens) | 6480464 | CTD | antimony trioxide results in increased activity of MAPK8 protein | PMID:16112521 | Mapk8 | multiple interactions | ISO | MAPK8 (Homo sapiens) | 6480464 | CTD | [antimony trioxide co-treated with Buthionine Sulfoximine] results in decreased expression of MAPK8 protein; Buthionine Sulfoximine promotes the reaction [antimony trioxide results in increased activity of MAPK8 protein]; Glutathione deficiency promotes the reaction [antimony trioxide results in increased activity of MAPK8 protein] | PMID:16112521 | Mapk8 | multiple interactions | ISO | Mapk8 (Mus musculus) | 6480464 | CTD | MAP2K4 protein affects the reaction [antimony trioxide results in increased activity of MAPK8 protein] | PMID:16112521 | | ||||||||||||||||||||||
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