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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2582
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Esr2
Name: estrogen receptor 2
Acc ID: CHEBI:78665
Term: royal jelly
Definition: A mixture secreted by the hypopharyngeal gland of young worker bees (Apis mellifera) and fed as it is secreted to the queen bee and to larvae that are being raised as potential queen bees; it is not stored. Water makes up about two thirds of fresh royal jelly, with the remainder consisting mostly of proteins and sugars, followed by lipids (mostly free fatty acids containing short (8 to 10 carbon atom) chains with uncommon structures) and water-soluble vitamins.
Chemical ID: MESH:C058787
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Esr2affects bindingISOESR2 (Homo sapiens)6480464CTDroyal jelly binds to ESR2 proteinPMID:17287592
Esr2multiple interactionsISOESR2 (Homo sapiens)6480464CTDEstradiol inhibits the reaction [royal jelly binds to ESR2 protein]; royal jelly binds to and results in increased activity of ESR2 protein; royal jelly inhibits the reaction [Estradiol binds to ESR2 protein]PMID:15946813 PMID:17287592
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