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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621405
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Hey2
Name: hes-related family bHLH transcription factor with YRPW motif 2
Acc ID: CHEBI:77733
Term: 2-(3,4-dimethoxyphenyl)-5-\{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino\}-2-(propan-2-yl)pentanenitrile
Definition: A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.
Chemical ID: MESH:D014700
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hey2multiple interactionsISOHey2 (Mus musculus)6480464CTDVerapamil promotes the reaction [Diethylhexyl Phthalate results in decreased expression of HEY2 mRNA]; Verapamil promotes the reaction [Diethylhexyl Phthalate results in decreased expression of HEY2 protein]; Verapamil promotes the reaction [Diethylhexyl Phthalate results in increased expression of HEY2 mRNA]PMID:31086358
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