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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1311750
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mettl3
Name: methyltransferase 3, N6-adenosine-methyltransferase complex catalytic subunit
Acc ID: CHEBI:75192
Term: thallium(I) acetate
Definition: An acetate salt comprising equal numbers of acetate and thallium ions.
Chemical ID: MESH:C026995
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mettl3increases expressionISOMETTL3 (Homo sapiens)6480464CTDthallium acetate results in increased expression of METTL3 proteinPMID:36745568
Mettl3multiple interactionsISOMETTL3 (Homo sapiens)6480464CTD3-deazaadenosine inhibits the reaction [thallium acetate results in increased expression of METTL3 protein]; METTL3 protein affects the reaction [thallium acetate results in increased expression of ATP13A3 protein]PMID:36745568
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