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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1593189
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Gsta5
Name: glutathione S-transferase alpha 5
Acc ID: CHEBI:6709
Term: Meclizine
Definition: A diarylmethane that has formula C25H27ClN2.
Chemical ID: MESH:D008468
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gsta5multiple interactionsISOGsta1 (Mus musculus)6480464CTD[Meclizine binds to and results in increased activity of NR1I3 protein] which results in increased expression of GSTA1 mRNAPMID:15272053
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