RGD ID: 619951
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Abcb1a
Name: ATP binding cassette subfamily B member 1A
Acc ID: CHEBI:6367
Term: lamotrigine
Definition: A member of the class of 1,2,4-triazines in which the triazene skeleton is substituted by amino groups at positions 3 and 5, and by a 2,3-dichlorophenyl group at position 6.
Definition Source(s): CAS:84057-84-1, CAS:84057-84-1, CAS:84057-84-1, Drug_Central:1540, DrugBank:DB00555, HMDB:HMDB0014695, KEGG:D00354, LINCS:LSM-4104, PMID:20825390, PMID:21242744, Reaxys:7589268, Wikipedia:Lamotrigine
Chemical ID: MESH:C047781
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases activityISORGD:7308236480464CTDlamotrigine results in decreased activity of ABCB1 protein

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