RGD ID: 2184
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Avp
Name: arginine vasopressin
Acc ID: CHEBI:49662
Term: indometacin
Definition: A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
Definition Source(s): Beilstein:497341, CAS:53-86-1, CAS:53-86-1, CAS:53-86-1, Drug_Central:1440, DrugBank:DB00328, Gmelin:1446006, HMDB:HMDB0014473, KEGG:C01926, KEGG:D00141, KNApSAcK:C00030512, LINCS:LSM-3275, MetaCyc:CPD-10545, Patent:BE379378, Patent:US3161654, PDBeChem:IMN, PMID:22931205, PMID:23992308, PMID:28166217, PMID:5952296, PMID:6039425, Reaxys:497341, Wikipedia:Indometacin
Chemical ID: MESH:D007213
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases secretionISORGD:689686480464CTDIndomethacin results in decreased secretion of AVP protein

Go Back to source page   Continue to Ontology report