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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735096
Species: Rattus norvegicus
RGD Object: Gene
Symbol: RT1-DMb
Name: RT1 class II, locus DMb
Acc ID: CHEBI:4887
Term: ethosuximide
Definition: A dicarboximide that is pyrrolidine-2,5-dione in which the hydrogens at position 3 are substituted by one methyl and one ethyl group. An antiepileptic, it is used in the treatment of absence seizures and may be used for myoclonic seizures, but is ineffective against tonic-clonic seizures.
Chemical ID: MESH:D005013
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
RT1-DMbaffects expressionISOHLA-DMB (Homo sapiens)6480464CTDEthosuximide affects the expression of HLA-DMB mRNAPMID:25811541
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