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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1351186
Species: Homo sapiens
RGD Object: Gene
Symbol: OR1A1
Name: olfactory receptor family 1 subfamily A member 1
Acc ID: CHEBI:47856
Term: citronellal
Definition: A monoterpenoid, the main component of citronella oil which gives it its distinctive lemon aroma.
Chemical ID: MESH:C108217
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
OR1A1affects bindingEXP 6480464CTDcitronellal binds to OR1A1 protein; OR1A1 protein binds to citronellalPMID:17601748 PMID:17681278
OR1A1affects bindingISOOr1a1b (Mus musculus)6480464CTDOR1A1B protein binds to citronellalPMID:17681278
OR1A1increases activityISOOr1a1b (Mus musculus)6480464CTDcitronellal results in increased activity of OR1A1B proteinPMID:15598656
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