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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2184
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Avp
Name: arginine vasopressin
Acc ID: CHEBI:4450
Term: desmopressin
Definition: A synthetic analogue of vasopressin in which 3-mercaptopropionic acid replaces the cysteine residue at position 1 and D-arginine replaces the residue at position 8. An antidiuretic, it increases urine concentration and decreases urine production, and is used (usually as the trihydrate of the acetic acid salt) to prevent and control excessive thirst, urination, and dehydration caused by injury, surgery, and certain medical conditions. It is also used in the diagnosis and treatment of cranial diabetes insipidus and in tests of renal function.
Chemical ID: MESH:D003894
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Avpmultiple interactionsISOAvp (Mus musculus)6480464CTD[Atrazine affects the metabolism of AVP protein] which results in increased abundance of Deamino Arginine VasopressinPMID:33485040
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