Gene Chemical Interaction Report - Rat Genome Database

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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID:	1311235
Species:	Rattus norvegicus
RGD Object:	Gene
Symbol:	Myl9
Name:	myosin light chain 9

Acc ID:	CHEBI:4450
Term:	desmopressin
Definition:	A synthetic analogue of vasopressin in which 3-mercaptopropionic acid replaces the cysteine residue at position 1 and D-arginine replaces the residue at position 8. An antidiuretic, it increases urine concentration and decreases urine production, and is used (usually as the trihydrate of the acetic acid salt) to prevent and control excessive thirst, urination, and dehydration caused by injury, surgery, and certain medical conditions. It is also used in the diagnosis and treatment of cranial diabetes insipidus and in tests of renal function.
Chemical ID:	MESH:D003894

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Object Symbol	Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
Myl9	increases phosphorylation	EXP		6480464	CTD	Deamino Arginine Vasopressin results in increased phosphorylation of MYL9 protein	PMID:15347643
Myl9	multiple interactions	EXP		6480464	CTD	ML 7 inhibits the reaction [Deamino Arginine Vasopressin results in increased phosphorylation of MYL9 protein]	PMID:15347643

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