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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621405
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Hey2
Name: hes-related family bHLH transcription factor with YRPW motif 2
Acc ID: CHEBI:4042
Term: cypermethrin
Definition: A carboxylic ester resulting from the formal condensation between 3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylic acid and the alcoholic hydroxy group of hydroxy(3-phenoxyphenyl)acetonitrile.
Chemical ID: MESH:C017160
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hey2decreases expressionISOHEY2 (Homo sapiens)6480464CTDcypermethrin results in decreased expression of HEY2 mRNAPMID:38582279
Hey2decreases expressionISOHey2 (Mus musculus)6480464CTDcypermethrin results in decreased expression of HEY2 mRNAPMID:38582279
Hey2multiple interactionsISOHEY2 (Homo sapiens)6480464CTDAcetylcysteine inhibits the reaction [cypermethrin results in decreased expression of HEY2 mRNA]PMID:38582279
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