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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620675
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Rps6ka1
Name: ribosomal protein S6 kinase A1
Acc ID: CHEBI:39382
Term: flufenoxuron
Definition: A benzoylurea insecticide that has formula C21H11ClF6N2O3.
Chemical ID: MESH:C067660
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Rps6ka1decreases phosphorylationISORps6ka1 (Mus musculus)6480464CTDflufenoxuron results in decreased phosphorylation of RPS6KA1 proteinPMID:33771252
Rps6ka1multiple interactionsISORps6ka1 (Mus musculus)6480464CTD2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [flufenoxuron results in decreased phosphorylation of RPS6KA1 protein]; U 0126 inhibits the reaction [flufenoxuron results in decreased phosphorylation of RPS6KA1 protein]PMID:33771252
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