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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 727850
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Kiss1
Name: KiSS-1 metastasis-suppressor
Acc ID: CHEBI:39098
Term: pyrethrins
Definition: The active insecticidal constituents of Chrysanthemum cinerariifolium flowers.
Chemical ID: MESH:D011722
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Kiss1affects expressionEXP 6480464CTDPyrethrins affects the expression of KISS1 proteinPMID:34896426
Kiss1increases expressionEXP 6480464CTDPyrethrins results in increased expression of KISS1 proteinPMID:36053783
Kiss1multiple interactionsISOKISS1 (Homo sapiens)6480464CTD[[Environmental Pollutants results in increased abundance of Pyrethrins] which results in increased abundance of 3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropane carboxylic acid] which results in decreased methylation of KISS1 gene; [[Environmental Pollutants results in increased abundance of Pyrethrins] which results in increased abundance of 3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropane carboxylic acid] which results in increased secretion of KISS1 protein alternative formPMID:36657687
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