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Pathways

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620683
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Rps6kb1
Name: ribosomal protein S6 kinase B1
Acc ID: CHEBI:35817
Term: roxarsone
Definition: An organoarsonic acid where the organyl group is 4-hydroxy-3-nitrophenyl.
Chemical ID: MESH:D012406
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Rps6kb1increases expressionEXP 6480464CTDRoxarsone results in increased expression of RPS6KB1 mRNAPMID:35985552
Rps6kb1multiple interactionsEXP 6480464CTDRoxarsone results in increased expression of and results in increased phosphorylation of RPS6KB1 protein; Sirolimus inhibits the reaction [Roxarsone results in increased expression of and results in increased phosphorylation of RPS6KB1 protein]PMID:35985552
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