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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 18621458
Species: Chlorocebus sabaeus
RGD Object: Gene
Symbol: SOD3
Name: superoxide dismutase 3
Acc ID: CHEBI:35696
Term: cobalt dichloride
Definition: A cobalt salt in which the cobalt metal is in the +2 oxidation state and the counter-anion is chloride. It is used as an indicator for water in desiccants.
Chemical ID: MESH:C018021
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
SOD3decreases expressionEXP 6480464CTDcobaltous chloride results in decreased expression of SOD3 mRNA; cobaltous chloride results in decreased expression of SOD3 proteinPMID:19031313
SOD3multiple interactionsEXP 6480464CTD6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [cobaltous chloride results in decreased expression of SOD3 mRNA]; SB 203580 inhibits the reaction [cobaltous chloride results in decreased expression of SOD3 mRNA]PMID:19031313
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