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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1309970
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Gsta4
Name: glutathione S-transferase alpha 4
Acc ID: CHEBI:34718
Term: 1-chloro-2,4-dinitrobenzene
Definition: A C-nitro compound that is chlorobenzene carrying a nitro substituent at each of the 2- and 4-positions.
Chemical ID: MESH:D004137
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gsta4affects bindingEXP 1641942RGD1-chloro-2 4-dinitrobenzene binds to Gsta4 protein 
Gsta4affects metabolic processingEXP 6480464CTDGSTA4 protein affects the metabolism of DinitrochlorobenzenePMID:2619714
Gsta4affects expressionISOGsta4 (Mus musculus)6480464CTDDinitrochlorobenzene affects the expression of GSTA4 mRNAPMID:28219650
Gsta4multiple interactionsISOGSTA4 (Homo sapiens)6480464CTD[GSTA1 protein binds to GSTA4 protein] which affects the metabolism of Dinitrochlorobenzene; [GSTA4 protein binds to GSTA4 protein] which affects the metabolism of DinitrochlorobenzenePMID:11851347
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