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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3401
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Prkg2
Name: protein kinase cGMP-dependent 2
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Prkg2affects methylationEXP 6480464CTDbisphenol A affects the methylation of PRKG2 promoterPMID:27415467
Prkg2decreases expressionEXP 6480464CTDbisphenol A results in decreased expression of PRKG2 mRNAPMID:25181051 PMID:34947998
Prkg2increases expressionISOPrkg2 (Mus musculus)6480464CTDbisphenol A results in increased expression of PRKG2 mRNAPMID:32156529
Prkg2increases expressionISOPRKG2 (Homo sapiens)6480464CTDbisphenol A results in increased expression of PRKG2 mRNAPMID:27685785
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