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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1307448
Species: Rattus norvegicus
RGD Object: Gene
Symbol: H4c14
Name: H4 clustered histone 14
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
H4c14decreases expressionISOH4C2 (Homo sapiens)6480464CTDbisphenol A results in decreased expression of H4C2 mRNAPMID:29275510
H4c14multiple interactionsISOH4C2 (Homo sapiens)6480464CTD[bisphenol A co-treated with Fulvestrant] results in increased methylation of H4C2 genePMID:31601247
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