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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1303330
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Prss57
Name: serine protease 57
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Prss57decreases expressionEXP 6480464CTDbisphenol A results in decreased expression of PRSS57 mRNAPMID:25181051
Prss57multiple interactionsEXP 6480464CTD[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate] affects the methylation of PRSS57 promoterPMID:23359474
Prss57decreases expressionISOPrss57 (Mus musculus)6480464CTDbisphenol A results in decreased expression of PRSS57 mRNAPMID:29161229
Prss57increases expressionISOPrss57 (Mus musculus)6480464CTDbisphenol A results in increased expression of PRSS57 mRNAPMID:22687993 PMID:30951980
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