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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1595926
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Il17d
Name: interleukin 17D
Acc ID: CHEBI:29865
Term: benzo[a]pyrene
Definition: An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Chemical ID: MESH:D001564
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Il17daffects methylationISOIL17D (Homo sapiens)6480464CTDBenzo(a)pyrene affects the methylation of IL17D intronPMID:30157460
Il17ddecreases expressionISOIl17d (Mus musculus)6480464CTDBenzo(a)pyrene results in decreased expression of IL17D mRNAPMID:27195522
Il17dincreases methylationISOIL17D (Homo sapiens)6480464CTDBenzo(a)pyrene results in increased methylation of IL17D 3' UTRPMID:27901495
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