RGD ID: 620218
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Creb1
Name: cAMP responsive element binding protein 1
Acc ID: CHEBI:28869
Term: menadione
Definition: A member of the class of 1,4-naphthoquinones that is 1,4-naphthoquinone which is substituted at position 2 by a methyl group. It is used as a nutritional supplement and for the treatment of hypoprothrombinemia.
Definition Source(s): CAS:58-27-5, CAS:58-27-5, CAS:58-27-5, Drug_Central:1683, DrugBank:DB00170, HMDB:HMDB0001892, KEGG:C05377, KEGG:D02335, LINCS:LSM-3755, PDBeChem:VK3, PMID:13779073, PMID:15052609, PMID:16469140, PMID:1650428, PMID:28166217, PMID:9380028, Reaxys:1908453, Wikipedia:Menadione
Chemical ID: MESH:D024483
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsISORGD:7308866480464CTD[sodium arsenite co-treated with Vitamin K 3] results in increased phosphorylation of CREB1 protein

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