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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1307069
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Abca8
Name: ATP binding cassette subfamily A member 8
Acc ID: CHEBI:28748
Term: doxorubicin
Definition: An anthracycline antibiotic that has formula C27H29NO11.
Chemical ID: MESH:D004317
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Abca8decreases expressionISOABCA8 (Homo sapiens)6480464CTDDoxorubicin results in decreased expression of ABCA8 mRNAPMID:29803840
Abca8increases expressionISOAbca8b (Mus musculus)6480464CTDDoxorubicin results in increased expression of ABCA8B mRNAPMID:26873546
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