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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1306447
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Samd8
Name: sterile alpha motif domain containing 8
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Samd8increases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in increased expression of SAMD8 mRNAPMID:21215274
Samd8decreases expressionISOSamd8 (Mus musculus)6480464CTDTetrachlorodibenzodioxin results in decreased expression of SAMD8 mRNAPMID:28213091
Samd8increases expressionISOSamd8 (Mus musculus)6480464CTDTetrachlorodibenzodioxin results in increased expression of SAMD8 mRNAPMID:19465110 PMID:24680724
Samd8multiple interactionsISOSamd8 (Mus musculus)6480464CTDTetrachlorodibenzodioxin promotes the reaction [AHR protein binds to SAMD8 gene]PMID:28213091
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