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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 68384
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ccnd1
Name: cyclin D1
Acc ID: CHEBI:27812
Term: Se-methyl-L-selenocysteine
Definition: An L-alpha-amino acid compound having methylselanylmethyl as the side-chain.
Chemical ID: MESH:C002979
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ccnd1decreases expressionEXP 6480464CTDselenomethylselenocysteine results in decreased expression of CCND1 mRNA; selenomethylselenocysteine results in decreased expression of CCND1 proteinPMID:11396176 PMID:19276161
Ccnd1decreases expressionISOCCND1 (Homo sapiens)6480464CTDselenomethylselenocysteine results in decreased expression of CCND1 proteinPMID:18855134
Ccnd1multiple interactionsISOCCND1 (Homo sapiens)6480464CTD[selenomethylselenocysteine co-treated with Tamoxifen] results in decreased expression of CCND1 proteinPMID:18855134
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