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Pathways

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 708540
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cxcl6
Name: C-X-C motif chemokine ligand 6
Acc ID: CHEBI:27363
Term: zinc atom
Definition: A zinc group element atom that has formula Zn.
Chemical ID: MESH:D015032
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cxcl6increases expressionEXP 6480464CTDZinc deficiency results in increased expression of CXCL5 mRNA; Zinc deficiency results in increased expression of CXCL5 proteinPMID:22689922
Cxcl6multiple interactionsISOCXCL6 (Homo sapiens)6480464CTD[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of CXCL6 mRNAPMID:16979875
Cxcl6multiple interactionsISOCxcl5 (Mus musculus)6480464CTD[Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of CXCL5 mRNA; TNF protein promotes the reaction [[Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of CXCL5 mRNA]PMID:23503329
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