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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 12399201
Species: Canis lupus familiaris
RGD Object: Gene
Symbol: PIK3CG
Name: phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
Acc ID: CHEBI:26034
Term: phosphatidylinositol 3-phosphate
Definition: A phosphatidylinositol monophosphate carrying the phosphate group at the 3-position.
Chemical ID: MESH:C055525
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
PIK3CGmultiple interactionsEXP 6480464CTD2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [[Norepinephrine results in increased activity of PIK3CG protein] which results in increased chemical synthesis of phosphatidylinositol 3-phosphate]; [Clonidine results in increased activity of PIK3CG protein] which results in increased chemical synthesis of phosphatidylinositol 3-phosphate; [Norepinephrine results in increased activity of PIK3CG protein] which results in increased chemical synthesis of phosphatidylinositol 3-phosphate; Yohimbine inhibits the reaction [[Clonidine results in increased activity of PIK3CG protein] which results in increased chemical synthesis of phosphatidylinositol 3-phosphate]PMID:15958164
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