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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2772
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Gusb
Name: glucuronidase, beta
Acc ID: CHEBI:230671
Term: misonidazole
Definition: null
Chemical ID: MESH:D008920
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gusbincreases activityEXP 6480464CTDMisonidazole results in increased activity of GUSB proteinPMID:7459223
Gusbincreases activityISOGusb (Mus musculus)6480464CTDMisonidazole results in increased activity of GUSB proteinPMID:6696821 PMID:7073948 PMID:7107415
Gusbmultiple interactionsISOGusb (Mus musculus)6480464CTDDexamethasone inhibits the reaction [Misonidazole results in increased activity of GUSB protein]; Flurbiprofen inhibits the reaction [Misonidazole results in increased activity of GUSB protein]; Phenytoin inhibits the reaction [Misonidazole results in increased activity of GUSB protein]PMID:6696821
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