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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2754
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Gsta2
Name: glutathione S-transferase alpha 2
Acc ID: CHEBI:183226
Term: (RS)-goitrin
Definition: A racemate composed of equimolar amounts of (R)- and (S)-goitrin. It is an antithyroid agent found in cabbage, rutabaga, turnip, and brassicaceous weeds.
Chemical ID: MESH:C004333
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gsta2increases expressionEXP 6480464CTDgoitrin results in increased expression of GSTA2 proteinPMID:7532609
Gsta2multiple interactionsEXP 6480464CTDTriiodothyronine inhibits the reaction [goitrin results in increased expression of GSTA2 protein]PMID:7532609
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