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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 12058559
Species: Canis lupus familiaris
RGD Object: Gene
Symbol: CYP2E1
Name: cytochrome P450 family 2 subfamily E member 1
Acc ID: CHEBI:17578
Term: toluene
Definition: The simplest member of the class toluenes consisting of a benzene core which bears a single methyl substituent.
Chemical ID: MESH:D014050
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CYP2E1affects metabolic processingEXP 6480464CTDCYP2E1 protein affects the metabolism of ToluenePMID:8592870
CYP2E1multiple interactionsEXP 6480464CTDDitiocarb inhibits the reaction [CYP2E1 protein affects the metabolism of Toluene]; Fomepizole inhibits the reaction [CYP2E1 protein affects the metabolism of Toluene]PMID:8592870
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