Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 727850
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Kiss1
Name: KiSS-1 metastasis-suppressor
Acc ID: CHEBI:17347
Term: testosterone
Definition: An androstanoid having 17beta-hydroxy and 3-oxo groups, together with unsaturation at C-4-C-5..
Chemical ID: MESH:D013739
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Kiss1increases secretionEXP 6480464CTDKISS1 protein modified form results in increased secretion of TestosteronePMID:32726590
Kiss1multiple interactionsEXP 6480464CTDKISS1 protein modified form inhibits the reaction [glucagon-like peptide 1 (7-36)amide analog results in decreased secretion of Testosterone]PMID:32726590
Kiss1affects expressionISOKiss1 (Mus musculus)6480464CTDTestosterone affects the expression of KISS1 proteinPMID:25269483
Kiss1decreases expressionISOKISS1 (Homo sapiens)6480464CTDTestosterone results in decreased expression of KISS1 mRNAPMID:33359661
Go Back to source page   Continue to Ontology report