RGD ID: 1558619
Species: Mus musculus
RGD Object: Gene
Symbol: Ctsb
Name: cathepsin B
Acc ID: CHEBI:17303
Term: morphine
Definition: A morphinane alkaloid that is a highly potent opiate analgesic psychoactive drug. Morphine acts directly on the central nervous system (CNS) to relieve pain but has a high potential for addiction, with tolerance and both physical and psychological dependence developing rapidly. Morphine is the most abundant opiate found in Papaver somniferum (the opium poppy).
Definition Source(s): Beilstein:93704, CAS:57-27-2, CAS:57-27-2, CAS:57-27-2, Drug_Central:1845, DrugBank:DB00295, KEGG:C01516, KEGG:D08233, KNApSAcK:C00001889, MetaCyc:MORPHINE, PDB:1Q0Y, PDBeChem:MOI, PMID:12593758, PMID:15019787, PMID:17171884, PMID:17667569, PMID:19371311, PMID:20071451, PMID:23292329, PMID:23325235, PMID:23555556, PMID:23927484, PMID:23988259, PMID:24096538, PMID:24306419, PMID:27735107, PMID:27815868, PMID:27866460, PMID:9231550, Reaxys:93704, Wikipedia:Morphine
Chemical ID: MESH:D009020
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionISORGD:6215096480464CTDMorphine results in increased expression of CTSB mRNA

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